“…The neuroticism personality showed genetic susceptibility to AD by exacerbating cognitive impairment (Zufferey et al, 2017 ), disturbing emotional fragility (Danielsdottir et al, 2019 ) and sleep difficulties (Stephan et al, 2020 ), which in turn makes people more susceptible to various cardiovascular diseases (Lee et al, 2022 ), all of which are high‐risk factors for AD (Andrews et al, 2021 ; Korologou‐Linden et al, 2019 ; Li et al, 2021 ; Stephan et al, 2018 ). Furthermore, neuroticism is an important risk factor for many psychiatric disorders, such as major depressive disorder and schizophrenia (Brainstorm Consortium et al, 2018 ; Genetics of Personality Consortium et al, 2015 ).…”