Neuropsychophysical optimization by REAC technology in the treatment of: sense of stress and confusion. Psychometric evaluation in a randomized, single blind, sham-controlled naturalistic study

Fontani, Vania; Aravagli, Lucia; Margotti, Matteo Lotti; Castagna, Alessandro; Mannu, Piero; Rinaldi, Salvatore

doi:10.2147/ppa.s29734

Cited by 14 publications

(8 citation statements)

References 23 publications

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“…The results obtained in this study, evaluated with the DASS test, confirm that REAC-NPO and -NPPO neuro-modulation treatments can be useful tools for the clinical treatment of depression, anxiety, and stress, as already proven by previous results evaluated with different psychometric tests 9–18,30…”

Section: Resultssupporting

confidence: 84%

<p>Radio electric asymmetric conveyer neuromodulation in depression, anxiety, and stress</p>

Rinaldi¹,

Rinaldi²,

Pereira³

et al. 2019

NDT

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Background The purpose of this study was to assess the efficacy of specific neuromodulation treatments performed with radio electric asymmetric conveyer (REAC) technology in the treatment of the symptomatic triad depression, anxiety, and stress by the use of a specific psychometric test such as the Depression Anxiety Stress Scale-42 items (DASS-42) version, which assesses simultaneously the severity of expression of this triad. Patients and methods The design of this study was planned to compare two populations that performed DASS-42 test twice within a similar period of time. The first population performed the first DASS test before the treatment and the second test about 3 months later, at the end of two specific REAC neuromodulation treatments, neuropostural optimization (NPO) and neuropsychophysical optimization (NPPO), that have previously shown an efficacy in the treatment of depression, anxiety and stress. The second population (untreated), used as the randomized control group, consisted of a similar group by gender and age, who performed the DASS-42 test in an online platform twice, with an interval of about 3 months between the first and second tests, similar to the interval between the two tests in the treated group. Results The comparison between the treated group and the control group points out the REAC treatment efficacy in improving the quality of life. At the second DASS-42 test, self-administered about 3 months after the treatments, treated patients were positioned on average values of much milder severity in all the three clusters, depression, anxiety, and stress, while in untreated patients there was no significant difference between the mean values of the first and second DASS tests. Conclusion The results obtained in this study, evaluated with the DASS-42 test, confirm that REAC-NPO and REAC-NPPO neuromodulation treatments can be useful tools for the clinical treatment of depression, anxiety, and stress, as already proven by previous results evaluated with different psychometric tests.

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Section: Resultssupporting

confidence: 84%

<p>Radio electric asymmetric conveyer neuromodulation in depression, anxiety, and stress</p>

Rinaldi¹,

Rinaldi²,

Pereira³

et al. 2019

NDT

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“…The REAC-NPPO protocol has proven to be effective in treating stress-related symptoms, 13 – 18 such as anxiety, 19 – 21 pain, 16 depression, 19 , 20 , 22 and other psychiatric disorders 23 – 25 also related to adaptation disorder. 13 , 26 – 28 These two REAC neuro-modulation protocols are absolutely non-invasive, painless and very fast and easy to be administered.…”

Section: Introductionmentioning

confidence: 99%

REAC neuromodulation treatments in subjects with severe socioeconomic and cultural hardship in the Brazilian state of Pará: a family observational pilot study

Pereira¹,

Rinaldi²,

Fontani³

et al. 2018

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PurposeThe purpose of this preliminary observational study was to evaluate the usefulness of a humanitarian initiative, aimed at improving the neuropsychological and behavioral attitude of children with severe socioeconomic and cultural hardship, in the Brazilian state of Pará. This humanitarian initiative was realized through the administration of two neuromodulation protocols, with radioelectric asymmetric conveyor (REAC) technology. During several years of clinical use, the REAC neuromodulation protocols have already proved to be effective in countering the effects of environmental stress on neuropsycho-physical functions.Patients and methodsAfter the preliminary medical examination, all subjects were investigated with the Strengths and Difficulties Questionnaire (SDQ), including the impact supplement with teacher’s report. After the SDQ, they received the neuromodulation treatment with REAC technology named neuro postural optimization (NPO), to evaluate their responsiveness. Subsequently, every 3 months all subjects underwent a treatment cycle of neuropsycho-physical optimization (NPPO) with REAC technology, for a total of three cycles. At the end of the last REAC-NPPO treatment cycle, all subjects were investigated once again with the SDQ. For the adequacy of the data, the Wilcoxon and the Signs tests were used. For the subdivision into clusters, the Kruskal–Wallis test was applied for the adequacy of the procedure. For all the applied tests, a statistical significance of p<0.5 was found.ResultsThe results showed that the REAC-NPO and REAC-NPPO neuromodulation protocols are able to improve the quality of life, the scholastic and socialization skills, and the overall state of physical and mental health in children of a family with severe socioeconomic and cultural hardship.ConclusionThe REAC-NPO and REAC-NPPO neuromodulation protocols, due to their non-invasive characteristics, painlessness, and speed of administration, can be hypothesized as a treatment to improve the overall state of physical and mental health in a large number of people with socioeconomic and cultural discomfort.

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“…The model used in this study (ASMED, Florence, Italy) is specific for regenerative treatment. REAC technology has demonstrated efficacy in ameliorating several stress-related disorders, 7 – 13 depression, 12 , 14 , 15 anxiety, 12 , 15 social anxiety, 16 agoraphobia, 17 bipolar disorder, 18 behavioral and psychiatric symptoms in Alzheimer’s disease, 19 and impaired motor control. 20 – 24 Recently, REAC technology using IVRTP has also demonstrated an ability to induce stem cell pluripotency and differentiation.…”

Section: Methodsmentioning

confidence: 99%

Regenerative treatment using a radioelectric asymmetric conveyor as a novel tool in antiaging medicine: an in vitro beta-galactosidase study

Rinaldi¹,

Maioli²,

Santaniello³

et al. 2012

CIA

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BackgroundBeta-galactosidase is the most widely used biomarker for highlighting the processes of cellular aging, including neurodegeneration. On this basis, we decided to test in vitro whether a set of rescuing/reparative events previously observed by us in subjects treated with radioelectric asymmetric conveyor (REAC) technology may also involve antagonism of a marker of aging-related degenerative processes, as assessed by a reduction in beta-galactosidase at the cellular level.MethodsHuman adipose-derived stem cells were cultured at different passages, ranging from 5 to 20, with or without REAC exposure for 12 hours. The cells were then processed for biochemical beta-galactosidase staining and morphological microscopy analysis.ResultsWe observed a significant reduction in expression of senescence associated-beta-galactosidase, and a persistence of fibroblast-like morphology typical of human adipose-derived stem cells, even at late passages.ConclusionOur results indicate the ability of REAC technology to counteract in vitro senescence of human adipose-derived stem cells, and prompt the hypothesis that such technology may be exploited to antagonize in vivo senescence of tissue-resident or transplanted stem cells playing an important role in clinical treatment of age-related processes.

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Neuropsychophysical optimization by REAC technology in the treatment of: sense of stress and confusion. Psychometric evaluation in a randomized, single blind, sham-controlled naturalistic study

Cited by 14 publications

References 23 publications

<p>Radio electric asymmetric conveyer neuromodulation in depression, anxiety, and stress</p>

<p>Radio electric asymmetric conveyer neuromodulation in depression, anxiety, and stress</p>

REAC neuromodulation treatments in subjects with severe socioeconomic and cultural hardship in the Brazilian state of Pará: a family observational pilot study

Regenerative treatment using a radioelectric asymmetric conveyor as a novel tool in antiaging medicine: an in vitro beta-galactosidase study

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Neuropsychophysical optimization by REAC technology in the treatment of: sense of stress and confusion. Psychometric evaluation in a randomized, single blind, sham-controlled naturalistic study

Cited by 14 publications

References 23 publications

<p>Radio electric asymmetric conveyer neuromodulation in depression, anxiety, and stress</p>

<p>Radio electric asymmetric conveyer neuromodulation in depression, anxiety, and stress</p>

REAC neuromodulation treatments in subjects with severe socioeconomic and cultural hardship in the Brazilian state of Par&aacute;: a family observational pilot study

Regenerative treatment using a radioelectric asymmetric conveyor as a novel tool in antiaging medicine: an in vitro beta-galactosidase study

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REAC neuromodulation treatments in subjects with severe socioeconomic and cultural hardship in the Brazilian state of Pará: a family observational pilot study