Neuropsychological state of the population living in the Aral Sea region (zone of ecological crisis)

Abstract

Background The Aral Sea crisis has led to harmful effects on human habitat. In recent years, mild cognitive impairment is a growing problem. Objectives This article provides the results of studying the neuropsychological state of residents living in the crisis zone of the Aral Sea region in the case of Shalkar city. We have provided an assessment of the neuropsychological state of examined population and determined the leading pathology in this region. Methods The survey sample included 344 persons of reproductive age from 21 to 45 years. We have obtained results in biochemical studies, indicating perturbations of proteometabolism and lipid metabolism. Results A correlation analysis showed dependence between a decrease of albumin and high-density lipoproteins, an increase of low-density lipoproteins and parameters of cognitive function. Conclusions The research suggests a high prevalence of cerebrovascular pathology among the population, changes in cognitive function parameters, long-term and short-term memory problems and high levels of depression.

Endotoxicosis After Psychological Correction

“…Similar phenomena reflecting the somatic and psychological state of the body are observed in various diseases, after childbirth, stress and are manifestations of endogenous intoxication (Kosareva et al, 2019;Meltzer-Brody et al, 2017;Sakiev et al, 2017), and their intensity gradually decreases as the pathological process regresses.…”

Chemical Mutagenesis and Cytogenetic Chromosomal Abnormalities in a Population Living in the Aral Sea region

“…Various researches show that pollution of the area near the Aral Sea by heavy metals affects the development of diseases of various organs and systems [6], [7], [8], [9], [10], [11], [12].…”

An analysis of deviations from international standards of physique development in male youngsters from the former aral sea region

“…Выраженным токсическим действием в отношении роста и развития человека обладают хлорорганические соединения (ХОС) [21] и высокие концентрации тяжелых металлов, в особенности свинца в почве и воде [26], источник которых остается предметом дискуссия и по сей день [22]. Данные вещества с пищей [22] попадают в кровь [19], абсорбируются в различных органах и тканях [9], могут быть причиной высокой заболеваемости у жителей Приаралья [20,28,34] и нарушения у них роста [3] и полового созревания [20].…”