Neuropsychiatric Findings in Patients Exposed to Polybrominated Biphenyls

Stross, Jeoffrey K.; Nixon, Robert K.; Anderson, Marvin D.

doi:10.1111/j.1749-6632.1979.tb56618.x

Cited by 13 publications

(4 citation statements)

References 3 publications

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“…These halogenated organic compounds are supplemental agents in a variety of consumer products, including electronic appliances, automotive parts, furniture, textiles, and plastic foams, intended to reduce fire-related injuries and property damage (Birnbaum and Staskal, 2004). Although these compounds have been recognized for their utility, the possible consequences for human health have been described in the scientific literature Landrigan et al, 1979;Meester, 1979;Rosenman et al, 1979;Silva et al, 1979;Stross et al, 1979;Valciukas et al, 1979;Wolff et al, 1979a;Wolff et al, 1979b;Bahn et al, 1980;Weil et al, 1981;Chanda et al, 1982;Kreiss et al, 1982;Eyster et al, 1983;Seagull, 1983;Jacobson et al, 1984;Lipson, 1987;Hoque et al, 1998;Blanck et al, 2000a;Blanck et al, 2000b;Sweeney et al, 2001;Blanck et al, 2002;Birnbaum and Staskal, 2004). Moreover, production of these compounds has increased dramatically over the last 20 years, and there is an increasing prevalence of exposure to brominated flame retardants worldwide (Birnbaum and Staskal, 2004).…”

Section: Introductionmentioning

confidence: 99%

Maternal exposure to polybrominated and polychlorinated biphenyls: Infant birth weight and gestational age

Givens¹,

Small²,

Terrell³

et al. 2007

Chemosphere

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Understanding the influence of maternal exposures on gestational age and birth weight is essential given that pre-term and/or low birth weight infants are at risk for increased mortality and morbidity. We performed a retrospective analysis of a cohort exposed to polybrominated biphenyls (PBB) through accidental contamination of cattle feed and polychlorinated biphenyls (PCB) through residual contamination in the geographic region. Our study population consisted of 444 mothers and their 899 infants born between 1975 and 1997. Using restricted maximum likelihood estimation, no significant association was found between estimated maternal serum PBB at conception or enrollment PCB levels and gestational age or infant birth weight in unadjusted models or in models that adjusted for maternal age, smoking, parity, infant gender, and decade of birth. For enrollment maternal serum PBB, no association was observed for gestational age. However, a negative association with high levels of enrollment maternal serum PBB and birth weight was suggested. We also examined the birth weight and gestational age among offspring of women with the highest (10%) PBB or PCB exposure, and observed no significant association. Because brominated compounds are currently used in consumer products and therefore, are increasingly prevalent in the environment, additional research is needed to better understand the potential relationship between in utero exposure to brominated compounds and adverse health outcomes.

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Section: Introductionmentioning

confidence: 99%

Maternal exposure to polybrominated and polychlorinated biphenyls: Infant birth weight and gestational age

Givens¹,

Small²,

Terrell³

et al. 2007

Chemosphere

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“…After the Michigan incident in 1973, several studies showed that workers in PBB industries were exposed to high concentrations of PBBs. Several of these studies also showed high exposure among workers on dairy farm from the surrounding areas (Bekesi et al, 1979a;Landrigan et al, 1979;Stross et al, 1979Stross et al, , 1981Wolff et al, 1979b). The Michigan population was more highly exposed than populations in other states.…”

Section: Occupational Exposurementioning

confidence: 96%

“…There are 209 possible structural congeners of the brominated biphenyl structure containing one or more bromines; however, only a few of these have been synthesized individually and characterized (Stepniczka, 1976;Sundström et al, 1976a). The number of PBB congeners that actually exist in commercial mixtures is much lower than that of polychlorinated biphenyls (PCB) congeners.…”

Section: Identification Of the Agentsmentioning

confidence: 99%

Polychlorinated biphenyls and polybrominated biphenyls

Walker¹

2001

Organic Pollutants

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initiated a programme on the evaluation of the carcinogenic risk of chemicals to humans involving the production of critically evaluated monographs on individual chemicals. The programme was subsequently expanded to include evaluations of carcinogenic risks associated with exposures to complex mixtures, lifestyle factors and biological and physical agents, as well as those in specific occupations. The objective of the programme is to elaborate and publish in the form of monographs critical reviews of data on carcinogenicity for agents to which humans are known to be exposed and on specific exposure situations; to evaluate these data in terms of human risk with the help of international working groups of experts in carcinogenesis and related fields; and to indicate where additional research efforts are needed. The lists of IARC evaluations are regularly updated and are available on the Internet at http:// monographs.iarc.fr/.This programme has been supported since 1982 by Cooperative Agreement U01 CA33193 with the United States National Cancer Institute, Department of Health and Human Services. Additional support has been provided since 1986 by the European Commission Directorate-General for Employment, Social Affairs, and Inclusion, initially by the Unit of Health, Safety and Hygiene at Work, and since 2014 by the European Union Programme for Employment and Social Innovation "EaSI" (2014-2020) The International Agency for Research on Cancer welcomes requests for permission to reproduce or translate its publications, in part or in full. Requests for permission to reproduce or translate IARC publications -whether for sale or for non-commercial distribution -should be addressed to the IARC Communications Group at: publications@iarc.fr.The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the Secretariat of the World Health Organization concerning the legal status of any country, territory, city, or area or of its authorities, or concerning the delimitation of its frontiers or boundaries.The mention of specific companies or of certain manufacturers' products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters.The IARC Monographs Working Group alone is responsible for the views expressed in this publication. IARC Library Cataloguing in Publication Data NOTE TO THE READERThe term 'carcinogenic risk' in the IARC Monographs series is taken to mean that an agent is capable of causing cancer. The Monographs evaluate cancer hazards, despite the historical presence of the word 'risks' in the title.Inclusion of an agent in the Monographs does not imply that it is a carcinogen, only that the published data have been examined. Equally, the fact that an agent has not yet been evaluated in a Monograph does not mean that...

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“…are also known to be associated with depression and anxiety, the interpretation of these self-reported symptoms has been questioned. 29 A study which purported to show that differences in neuropsychological functioning between exposed and control subjects could be accounted for by personality variables, however, failed to control for age, sex, education, or PBB exposure of control subjects. 30 A study of Michigan farm children found, like the studies of adults, a greater frequency of symptoms reported during the period from 1973 to 1976.3' A more detailed analysis of the symptoms reported for 1976, however, revealed an inverse relationship between number of symptoms reported and the measured level of serum PBB.…”

Section: Introductionmentioning

confidence: 99%

Developmental abilities of children exposed to polybrominated biphenyls (PBB).

Seagull¹

1983

Am J Public Health

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correlations were significant at p < .05. Multivariate analysis of covariance confirmed the existence of a significant main effect for fat PBB level, with parental education held constant. Children with higher body burdens of PBB (> .100 ppm) scored significantly lower than exposed children with lower body burdens on the same four tests, and on a composite score representing overall performance. These results suggest the existence of an inverse relationship between body levels of PBB and some developmental abilities in young children. (Am J Public Health 1983; 73:28 1-285.)

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Neuropsychiatric Findings in Patients Exposed to Polybrominated Biphenyls

Cited by 13 publications

References 3 publications

Maternal exposure to polybrominated and polychlorinated biphenyls: Infant birth weight and gestational age

Maternal exposure to polybrominated and polychlorinated biphenyls: Infant birth weight and gestational age

Polychlorinated biphenyls and polybrominated biphenyls

Developmental abilities of children exposed to polybrominated biphenyls (PBB).

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