2004
DOI: 10.1016/j.lfs.2004.06.001
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Neuroprotective effects of Ptychopetalum olacoides Bentham (Olacaceae) on oxygen and glucose deprivation induced damage in rat hippocampal slices

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Cited by 39 publications
(24 citation statements)
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“…Muirapuama is used in the North of Brazil as a nerve tonic and to increase physical and sexual performance. Studies with standardized extracts of its roots showed antioxidant, neuroprotective, anti-stress properties, and reversal in states of induced amnesia Siqueira et al, 2004;Piato et al, 2010).…”
Section: Brazilian Plants With An Adaptogen Profilementioning
confidence: 98%
“…Muirapuama is used in the North of Brazil as a nerve tonic and to increase physical and sexual performance. Studies with standardized extracts of its roots showed antioxidant, neuroprotective, anti-stress properties, and reversal in states of induced amnesia Siqueira et al, 2004;Piato et al, 2010).…”
Section: Brazilian Plants With An Adaptogen Profilementioning
confidence: 98%
“…Initially it was found to show effects as an anxiogenic (Silva et al, 2002), anticholinesterase (Siqueira et al, 2003), neuroprotective (Siqueira et al, 2004), facilitation of memory recovery in young and old mice (Silva et al, 2004), antioxidant (Siqueira et al, 2007), antidepressant (Paiva et al, 1998;Piato et al, 2009), and anti-stress (Piato et al, 2010). Its aphrodisiac potential has not been confi rmed experimentally or clinically, although some of its effects, such as antidepressant and antioxidant activity, may improve sexual performance (Feldman et al, 1994).…”
Section: Introductionmentioning
confidence: 99%
“…We reported that P. olacoides standardized ethanol extract (POEE), a standardized ethanol extract obtained from P. olacoides, possesses various CNS-relevant properties, including antioxidant (Siqueira et al 2007) and neuroprotective (Siqueira et al 2004) activities. Regarding cognition, we showed that POEE facilitates short-term and long-term memories (inhibitory avoidance and object recognition) in adult and aged mice (da Silva et al 2004.…”
Section: Introductionmentioning
confidence: 99%