Neuroprotective effect of Sesbania sesban on Scopolamine induced amnesia in wistar rats: Behavioral and biochemical study

Abstract

Objective: The present work was carried out to evaluate the effects of hydroalcoholic extract of Sesbania sesban (HAESS) on cognitive impaired rats.In wistar rat's amnesia was induced by subcutaneous Materials and methods: administration of scopolamine butyl bromide (1mg/kg). Nootropic activity evaluated in terms of Spatial memory using T maze spontaneous alternation task.HAESS (400mg/kg) have shown significant level Results and conclusion: improvement in scopolamine-induced deficit with respect to recognition in spatial memory. The observed results suggest that hydroalcoholic extract of aerial parts of improves cognitive performance with respect to Sesbania sesban spatial memory processes.