Neurophysiological assessment of spinal cord injuries in dogs using somatosensory and motor evoked potentials

Souza, Maria Cláudia Campos Mello Inglez de; Ferreira, Roberta Machado; Patricio, Geni Cristina Fonseca; Matera, Júlia Maria

doi:10.1186/s13028-017-0305-0

Cited by 4 publications

(3 citation statements)

References 38 publications

(69 reference statements)

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“…EEG is particularly suitable for amputees due to its non-invasiveness, portability and safety [11]. Their uses in studying the cortical responses to tactile stimulation [12] and investigating the functionality of ascending sensory pathways [13,14] have been reported. EEG studies of neural oscillations accompanying tactile stimulation revealed the functional role of different oscillating rhythms such as alpha [15] and beta [9] rhythms.…”

Section: Introductionmentioning

confidence: 99%

Contra-lateral desynchronized alpha oscillations linearly correlate with discrimination performance of tactile acuity

Su¹,

Chai²,

Sheng³

et al. 2020

J. Neural Eng.

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Objective. We used EEG to investigate cortical oscillatory activities during the tactile discrimination task and characterize the correlation between the EEG features and subjects’ discrimination performance. Approach. Transcutaneous electrical nerve stimulation (TENS) was applied on two finger areas (thumb and index for healthy hands, thumb and index-projected areas for disabled hands) to evoke two kinds of tactile sensations (vibration and pressure) with three levels of intensities (low, medium and high). Four forearm amputees and thirteen able-bodied subjects were recruited to discriminate the specific intensity and area of the applied stimulation. We assessed the discrimination performance [discrimination accuracy rate (AR) and response time (RT)] to quantify the tactile acuity. During the stimulation, EEG signals were recorded and the evoked cortical oscillatory activities were analyzed. Linear regression analyses were performed between EEG features and tactile discrimination performance. Main results. Spectral analysis revealed that alpha ERD over somatosensory regions persisted the whole task period and was related to the sensory information processing. Alpha ERD over prefrontal regions was only found during the stimulation judgement period and might reflect advanced cognitive process. There was no linear correlation between prefrontal alpha ERD and tactile discrimination performance. While contralateral somatosensory alpha ERDs exhibited significantly negative correlations with ARs () and positive correlations with RTs (). Specifically, the fitting results of higher alpha band (10–13 Hz) were superior to lower alpha band (8–10 Hz). Significance. Alpha ERD over contralateral somatosensory cortex could be used as an objective index for the evaluation of tactile acuity and might have the potential to be applied in sensory rehabilitation for amputees.

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Section: Introductionmentioning

confidence: 99%

Contra-lateral desynchronized alpha oscillations linearly correlate with discrimination performance of tactile acuity

Su¹,

Chai²,

Sheng³

et al. 2020

J. Neural Eng.

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show abstract

“…However, it is meaningful to propose another electrophysiological index to evaluate the tactile acuity of either unilateral hand. Previous literature has used the feature of somatosensory evoked potentials (SEP) for the detection of the spinal cord injury [28,73,74]. SEP and tactile acuity are both related to the functionality of the ascending sensory pathways.…”

Section: Future Workmentioning

confidence: 99%

“…Electroencephalography (EEG) has attracted wide attention as an electrophysiological imaging tool. It is mainly used in evaluating neurological disorders clinically and investigating brain functions in the laboratory [27,28]. EEG and related methods are known to be portable and have relatively high temperate resolution.…”

Section: Introductionmentioning

confidence: 99%

Electrical stimulation-induced SSSEP as an objective index to evaluate the difference of tactile acuity between the left and right hand

Chai

Shu

et al. 2020

J. Neural Eng.

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Objective. The objective of this study is to propose an objective index to evaluate the difference of tactile acuity between the left and right hand based on steady-state somatosensory evoked potential (SSSEP). Approach. Two kinds of tactile sensations (vibration and pressure) with three levels of intensities (low/medium/high) were evoked on two finger areas of the left or right hand (thumb and index for healthy hands, thumb and index-projected areas for disabled hands) via transcutaneous electrical nerve stimulation (TENS). Three forearm amputees and 13 able-bodied subjects were recruited to discriminate the specific level and area of the applied stimulation. Electroencephalography was adopted to simultaneously record the somatosensory cortex response to TENS. We assessed the discrimination performance (discrimination accuracy rate (AR) and response time (RT)) to quantify the tactile acuity, while the evoked SSSEP was synchronously analyzed. Linear regression analyses were performed between the difference of SSSEP amplitudes and the difference of discrimination performance for the left and right hand stimulation. Main results. Frequency domain analysis revealed that SSSEP amplitude increased with the increase of the stimulation intensity. There were positive correlations between the difference of SSSEP amplitudes and the difference of ARs for the left and right hand stimulation in the sensations of vibration (R2 = 0.6389 for able-bodied subjects, R2 = 0.5328 for amputees) and pressure (R2 = 0.6102 for able-bodied subjects, R2 = 0.5452 for amputees), respectively. Significance The SSSEP amplitude could be used as an objective index to evaluate the difference of the tactile acuity between the left and right hand and has the potential to be applied in sensory rehabilitation for amputees or stroke patients.

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The effects of walking training onset on motor evoked potentials after acute spinal cord injury

Zhao

Zhou

Liu

et al. 2020

Neuroscience Letters

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Neurophysiological assessment of spinal cord injuries in dogs using somatosensory and motor evoked potentials

Cited by 4 publications

References 38 publications

Contra-lateral desynchronized alpha oscillations linearly correlate with discrimination performance of tactile acuity

Contra-lateral desynchronized alpha oscillations linearly correlate with discrimination performance of tactile acuity

Electrical stimulation-induced SSSEP as an objective index to evaluate the difference of tactile acuity between the left and right hand

The effects of walking training onset on motor evoked potentials after acute spinal cord injury

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