Neuromuscular ultrasound in clinical practice: A review

González, Natalia; Hobson‐Webb, Lisa D.

doi:10.1016/j.cnp.2019.04.006

Cited by 59 publications

(66 citation statements)

References 114 publications

(159 reference statements)

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“…At rst, QMUS is only suited for displaying super cial muscle layers, the reference values cannot set up reliably for deeper muscles. The second, QMUS cannot distinguish the abnormal signal intensities because of in ammation, brosis, or fatty in ltration [15]. Composite biomarkers, QMUS and impedance electromyography, may provide a more effective means for tracking the disease progression and therapeutic responses of DMD [16].…”

Section: Discussionmentioning

confidence: 99%

Quantitative Muscle Ultrasound versus Magnetic Resonance Imaging in Duchenne Muscular Dystrophy

Hu¹,

Jiang²,

Hong³

et al. 2020

Preprint

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Background: Nowadays, it needs favorable biomarkers to follow up the disease progression and therapeutic responses of Duchenne muscular dystrophy (DMD). This study evaluates which one of Quantitative muscle ultrasound (QMUS) and magnetic resonance imaging (MRI) is suitable for the disease in China. Methods: Thirty-six boys with DMD engaged in the longitudinal observational cohort study, who used prednisone from baseline to 12th month. Muscle thickness (MT) and echo intensity (EI) of QMUS and T1-weighted MRI grading were measured in the right quadriceps femoris of the boys with DMD. Results: The scores of MT and EI of QMUS and T1-weighted MRI grading showed significant correlations with the clinical ones of muscle strength, timed testing, and quality of life. The scores of MT and EI of QMUS showed good correlations with the ones of T1-weighted MRI grading too (P<0.05). But 15 of 36 boys with DMD did not take MRI examinations for different reasons. Conclusions: QMUS and MRI can use as biomarkers for tracking DMD. Nevertheless, QMUS, because of its practical, low cost, and patient-friendly, applies for DMD widely than MRI in China. Keywords: Ultrasonography, Magnetic resonance imaging, Duchenne muscular dystrophy, Child

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Section: Discussionmentioning

confidence: 99%

Quantitative Muscle Ultrasound versus Magnetic Resonance Imaging in Duchenne Muscular Dystrophy

Hu¹,

Jiang²,

Hong³

et al. 2020

Preprint

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“…In compressive neuropathies, localised enlargement, just proximal to the site of compression, decreased echogenicity, loss of the internal fascicular structure and increased blood flow, can all be commonly observed[ 3 , 65 ]. However, a maximum point of enlargement should be identified along the course proximal and distal to the site of compression, as enlargement can be present distal to the entrapment site, and nerve mobility may alter the positioning of such enlargements[ 66 ]. The entrapment site may display an hour-glass or spindle-shaped appearance in longitudinal views[ 66 ].…”

Section: Us Appearances In Peripheral Nerve Disordersmentioning

confidence: 99%

“…However, a maximum point of enlargement should be identified along the course proximal and distal to the site of compression, as enlargement can be present distal to the entrapment site, and nerve mobility may alter the positioning of such enlargements[ 66 ]. The entrapment site may display an hour-glass or spindle-shaped appearance in longitudinal views[ 66 ]. Strictures, ganglion cysts, tumours, thrombosed arteries and other extrinsically or intrinsically compressive lesions can be identified by US as the cause of symptomatology, and hence can drastically alter the management paradigm.…”

Section: Us Appearances In Peripheral Nerve Disordersmentioning

confidence: 99%

Current and future applications of ultrasound imaging in peripheral nerve disorders

Carroll¹,

Simon²

2020

WJR

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Neuromuscular ultrasound (NMUS) is a rapidly evolving technique used in neuromuscular medicine to provide complimentary information to standard electrodiagnostic studies. NMUS provides a dynamic, real time assessment of anatomy which can alter both diagnostic and management pathways in peripheral nerve disorders. This review describes the current and future techniques used in NMUS and details the applications and developments in the diagnosis and monitoring of compressive, hereditary, immune-mediated and axonal peripheral nerve disorders, and motor neuron diseases. Technological advances have allowed the increased utilisation of ultrasound for management of peripheral nerve disorders; however, several practical considerations need to be taken into account to facilitate the widespread uptake of this technique.

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“…Previous studies have shown that muscle ultrasound can differentiate between neuropathy and myopathy [6]. Moreover, Adler et al .…”

Section: Figurementioning

confidence: 99%

“…Previous studies have shown that muscle ultrasound can differentiate between neuropathy and myopathy [6]. Moreover, Adler et al described a target-like appearance, with increased central echogenicity and peripheral sparing of examined muscles on ultrasound in patients with GNE myopathy [7].…”

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confidence: 99%

A case of GNE myopathy mimicking hereditary motor neuropathy

Huang

Chuang

Hsueh

et al. 2020

Euro J of Neurology

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A 36‐year‐old woman who presented with upper limb distal weakness since the age of 15 years, with gradual progression to the lower limbs, is reported. Hereditary motor neuropathy was initially suspected based on distal weakness and hyporeflexia; however, whole exome sequencing accidentally revealed a compound heterozygous variant in the GNE gene, and ultrasound revealed increased homogeneous echogenicity in the involved muscles, which is characteristic of myopathic changes. Muscle magnetic resonance imaging revealed fatty infiltration in all limb muscles, sparing the triceps brachii, vastus lateralis and vastus medialis. Muscle biopsy revealed intracytoplasmic rimmed vacuole, supporting the diagnosis of GNE myopathy.

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Neuromuscular ultrasound in clinical practice: A review

Abstract: HighlightsNeuromuscular ultrasound (NMUS) augments clinicians’ diagnostic capabilities.NMUS requires a basic understanding of ultrasound technology and relevant anatomy.Uses include evaluation of neuropathies, myopathies, and motor neuron diseases.

Cited by 59 publications

References 114 publications

Quantitative Muscle Ultrasound versus Magnetic Resonance Imaging in Duchenne Muscular Dystrophy

Quantitative Muscle Ultrasound versus Magnetic Resonance Imaging in Duchenne Muscular Dystrophy

Current and future applications of ultrasound imaging in peripheral nerve disorders

A case of GNE myopathy mimicking hereditary motor neuropathy

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