Neurological Complications of Anticoagulation Therapy

Silverstein, Allen

doi:10.1001/archinte.1979.03630390069025

Cited by 64 publications

(4 citation statements)

References 58 publications

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“…24,[32][33][34][35][36] The specific use of anticoagulants such as coumadin and low-molecular-weight heparin for the prophylaxis of deep-vein thrombosis has not been associated with the formation of a symptomatic haematoma, but we found that patients who were coagulopathic from the procedure itself or from overmedication with anticoagulants had a higher risk of post-operative spinal epidural haematoma. This suggests that using anticoagulation post-operatively is safe as long as its use is monitored carefully.…”

Section: Discussionmentioning

confidence: 68%

Analysis of the risk factors for the development of post-operative spinal epidural haematoma

Awad

Kebaish

Donigan

et al. 2005

The Journal of Bone and Joint Surgery. British volume

206

225

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In order to identify the risk factors and the incidence of post-operative spinal epidural haematoma, we analysed the records of 14 932 patients undergoing spinal surgery between 1984 and 2002. Of these, 32 (0.2%) required re-operation within one week of the initial procedure and had an International Classification of Diseases (ICD)-9 code for haematoma complicating a procedure (998.12). As controls, we selected those who had undergone a procedure of equal complexity by the same surgeon but who had not developed this complication. Risks identified before operation were older than 60 years of age, the use of pre-operative non-steroidal anti-inflammatories and Rh-positive blood type. Those during the procedure were involvement of more than five operative levels, a haemoglobin < 10 g/dL, and blood loss > 1 L, and after operation an international normalised ratio > 2.0 within the first 48 hours. All these were identified as significant (p < 0.03). Well-controlled anticoagulation and the use of drains were not associated with an increased risk of post-operative spinal epidural haematoma.

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Section: Discussionmentioning

confidence: 68%

Analysis of the risk factors for the development of post-operative spinal epidural haematoma

Awad

Kebaish

Donigan

et al. 2005

The Journal of Bone and Joint Surgery. British volume

206

225

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“…Data about epidural bleeding and subarachnoid haemorrhage, the rarer manifestations of intracranial extracerebral haemorrhages, are also scarce. 22 24 25 30 31 34 36 Apart from mortality'8 21 4-26 35 systematic analyses of the outcome of patients suffering such bleeds during anticoagulant treatment are lacking. The present study presents a description and analysis of a large group of intracranial, extracerebral bleeds related to anticoagulation.…”

mentioning

confidence: 99%

Anticoagulation-related intracranial extracerebral haemorrhage.

Mattle

Köhler

Huber

et al. 1989

Journal of Neurology, Neurosurgery & Psychiatry

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“…Subdural hematomas form the most common complication of anticoagulation therapy with an incidence of 12-38% [10]. To the best of our knowledge, only six cases of posterior fossa subdural hematoma which are associated with anticoagulation usage have been reported so far in the literature [11][12][13][14][15] (Table 1).…”

Section: Discussionmentioning

confidence: 99%

Bilateral Sub-acute Subdural Hematoma of the Posterior Fossa As a Complication of Anti-coagulation Therapy: A Case Report and Literature Review

Ahmed¹,

Ibrahim²,

Mohammed³

et al. 2022

Sudan JMS

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Background: Subdural hematomas are one of the commonest neurosurgical pathologies faced in practice and it is rarely located in the posterior fossa. Posterior fossa subdural hematomas are challenging because of the difficulty in their diagnosis and management. Case Presentation: A case of bilateral sub-acute subdural hematoma of the posterior fossa in a 65-year-old female presented with a complaint of headache and vomiting for three weeks followed by a decreased level of consciousness two days prior to admission. The patient is a known cardiac patient on long-term anti-coagulant, her condition was intensively investigated and the diagnosis of posterior fossa subacute hematoma was reached, following which the patient was treated surgically and improved in the postoperative period. Conclusion: Subdural hematomas located in posterior fossa are considered very rare. Most of the reported cases are due to anti-coagulant use, with minor number of cases due to trauma. Literature denoted difficulty reaching diagnosis using only computed tomography and advice to be aided by magnetic resonance imaging as in our case. In most occasions, surgical management is the best choice for the management of such a case, regardless of surgical technique, and will result in excellent outcome.

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Neurological Complications of Anticoagulation Therapy

Cited by 64 publications

References 58 publications

Analysis of the risk factors for the development of post-operative spinal epidural haematoma

Analysis of the risk factors for the development of post-operative spinal epidural haematoma

Anticoagulation-related intracranial extracerebral haemorrhage.

Bilateral Sub-acute Subdural Hematoma of the Posterior Fossa As a Complication of Anti-coagulation Therapy: A Case Report and Literature Review

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