Neurological complications of acute leukaemia in an adult

MacDougall, Rosemary

doi:10.1016/0022-510x(64)90005-x

Journal of the Neurological Sciences

1964

DOI: 10.1016/0022-510x(64)90005-x

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Neurological complications of acute leukaemia in an adult

Rosemary MacDougall

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1966

1981

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Cited by 4 publications

References 19 publications

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Spinal cord involvement in leukemia: A review of the literature and a case of Ph1 + acute myeloid leukemia presenting with a conus medullaris syndrome

Petursson

Boggs

1981

Cancer

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A 21-year-old male with Ph1 positive acute myeloid leukemia (AML) became constipated, experienced pain in the sacral area and retained urine. These were the principle presenting complaints of his disease. With local radiotherapy and systemic chemotherapy, all neurologic symptoms and signs disappeared within three days. A conus medullaris syndrome is uncommon in leukemia, as we were able to find only three other such patients in the literature and three others with the closely related cauda equina syndrome. A literature review of spinal cord involvement in leukemia in general revealed 67 reasonably well-described cases. Compilation of data from these suggests it is most often seen in patients with AML and that it is most common in the second decade of life. Tumors extrinsic to but compressing the cord are the most common finding and the thoracic cord is the most common site of involvement.

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Spinal cord involvement in leukemia: A review of the literature and a case of Ph1 + acute myeloid leukemia presenting with a conus medullaris syndrome

Petursson

Boggs

1981

Cancer

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Methotrexate in Meningeal Leukæmia

Baikie

Spiers

1967

The Lancet

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An Autopsy Case of Acute Myelogenous Leukemia associated with Ascending Transverse Spinal Syndrome and Review of the Literature

Shibasaki¹,

Takeuchi²,

Sasaki³

et al. 1966

Neurol. Med. Chir.(Tokyo)

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The involvement of the nervous system has been noted in 20 to 60 per cent of leukemias32, 40.43.71,85,94,101,112). However, the spinal involvement is less common (5 per cent) 70,102,106). There have been about 95 reports of such complication in the Western countries since the report of Burns (1824)1w, and 40 of such in Japan.The purpose of this paper is to report of our recent case of myelogenouss leukemia with spinal complication, and to discuss the pathogenesis of such complication, reviewing the literature.

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Neurological complications of acute leukaemia in an adult

Cited by 4 publications

References 19 publications

Spinal cord involvement in leukemia: A review of the literature and a case of Ph1 + acute myeloid leukemia presenting with a conus medullaris syndrome

Spinal cord involvement in leukemia: A review of the literature and a case of Ph1 + acute myeloid leukemia presenting with a conus medullaris syndrome

Methotrexate in Meningeal Leukæmia

An Autopsy Case of Acute Myelogenous Leukemia associated with Ascending Transverse Spinal Syndrome and Review of the Literature

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