Neurologic Manifestations of Infective Endocarditis

Abstract

Our results reinforce the belief that rapid diagnosis and initiation of antimicrobial therapy may still be the most effective means to prevent neurologic complications. These data underscore the importance of diagnostic alertness to the prognosis of patients with IE.

A review of the role of anticoagulation for patients with infective endocarditis and embolic stroke

“…Several case series show that the majority of neurological complications occured before the initiation of antibiotic therapy. As such, the most important intervention to prevent further stroke is the initiation of antibiotic therapy 1, 2.…”

“…Embolic complications can affect many organs, but ischaemic stroke is one of the most common, occurring in 16% of patients in one series 2. We report a patient with infective endocarditis and stroke, because it is important for clinicians to be familiar with this presentation, so that the diagnosis is not delayed.…”

Infective endocarditis complicated with cerebral and splenic infarction in a hemodialysis patient

“…[1] Neurological complications of IE are almost always due to embolization, which include strokes, TIA, meningitis, intracranial hemorrhage, or encephalopathy. [5] The central nervous system is the most common site for embolic events, with up to 65% occurring there. [4]…”

Heart diseases and strokes in young people

“…Инсульт как осложнение ИЭ -результат эм-болизации эндокардиальных вегетаций с последовательной окклюзией внутримозговых артерий. Распространение эм-болии в церебральных или оболочечных сосудах может при-вести к менингиту или формированию внутримозгового абс-цесса [38,39]. Спектр неврологических событий включает ишемический инфаркт с кровотечением или без него, тран-зиторные ишемические атаки (ТИА), менингит, энцефало-патию, мозговой абсцесс, периферическую невропатию, апоплексический удар и редкие грибковые аневризмы.…”