Neurodevelopmental Outcome of Extremely Low Birth Weight Infants With Posthemorrhagic Hydrocephalus Requiring Shunt Insertion

Adams‐Chapman, Ira; Hansen, Nellie I.; Stoll, Barbara J.; Higgins, Rosemary

doi:10.1542/peds.2007-0423

Cited by 274 publications

(199 citation statements)

References 38 publications

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“…17 In a large cohort of extremely low birth weight infants, those with Papile grade 3 intraventricular hemorrhage who required a shunt were at twice the risk of cerebral palsy compared to those who did not. 18 A likely intermediate is white matter damage 19 which was associated with intraventricular hemorrhage in the present study. To the extent that intraventricular hemorrhage is causally related to white matter damage, it very likely is an important antecedent of developmental impairments, particularly cerebral palsy.…”

Section: Discussionsupporting

confidence: 52%

Intraventricular Hemorrhage and Developmental Outcomes at 24Months of Age in Extremely Preterm Infants

Papile¹

2012

Yearbook of Neonatal and Perinatal Medicine

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Whether intraventricular hemorrhage increases the risk of adverse developmental outcome among premature infants is controversial. Using brain ultrasound, we identified IVH and white matter abnormalities among 1064 infants born before 28 weeks gestation. We identified adverse developmental outcomes at 24 months of age using a standardized neurological examination and the Bayley Scales of Infant Development Mental and Motor Scales. In logistic regression models that adjusted for gestational age, sex, and public insurance, isolated intraventricular hemorrhage was associated with visual fixation difficulty (odds ratio: 2.5 (95% confidence limits: 1.2, 5.1)) but no other adverse outcome. Infants who had a white matter lesion unaccompanied by intraventricular hemorrhage were at increased risk of cerebral palsy, low Mental and Motor Scores, and visual and hearing impairments. Except when accompanied or followed by a white matter lesion, intraventricular hemorrhage is associated with no more than a mild increase (and possibly no increase) in the risk of adverse developmental outcome during infancy.

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Section: Discussionsupporting

confidence: 52%

Intraventricular Hemorrhage and Developmental Outcomes at 24Months of Age in Extremely Preterm Infants

Papile¹

2012

Yearbook of Neonatal and Perinatal Medicine

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“…This process resulted in 20 studies deemed eligible for inclusion. [14][15][16]19,[27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42] Additionally, 1 study 43 was identified and deemed eligible through searching references of included studies, bringing the final total to 21. Baseline characteristics of the 21 included studies are as shown in Supplemental Information 2.…”

Section: Description Of Studiesmentioning

confidence: 99%

“…[14][15][16]27,30,31,43 The results from the unadjusted meta-analyses are shown in Fig 3A, and the adjusted meta-analyses are as depicted in Fig 3B. Results from meta-analysis of unadjusted and adjusted ORs (where available) for death, CP, and cognitive delay are reported in Table 2.…”

Section: Primary Outcome: Death or Moderate To Severe Ndi At 18 To 24mentioning

confidence: 99%

Periventricular/Intraventricular Hemorrhage and Neurodevelopmental Outcomes: A Meta-analysis

2015

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CONTEXT: Periventricular/intraventricular hemorrhage (PIVH) is a common short-term morbidity in preterm infants, but its long-term neurodevelopmental impact, particularly with mild PIVH, remains unclear. STUDY SELECTION: Studies reporting long-term neurodevelopmental outcomes based on severity of PIVH were included.DATA EXTRACTION: Study characteristics, inclusion/exclusion criteria, exposures, and outcome assessment data extracted independently by 2 coauthors. RESULTS:The pooled unadjusted odds ratios of the primary outcome of death or moderate-severe neurodevelopmental impairment (NDI) were higher with both mild (1.48, 95% CI 1.26-1.73; 2 studies) and severe PIVH (4.72, 4.21-5.31; 3 studies); no studies reported adjusted odds ratios. Among survivors, odds of moderate-severe NDI were higher with mild and severe PIVH in both unadjusted (1.75, 1.40-2.20; 3 studies; 3.36, 3.06-3.68; 5 studies) and adjusted (1.39, 1.09-1.77; 3 studies; 2.44, 1.73-3.42; 2 studies) pooled analyses. Adjusted odds of cerebral palsy and cognitive delay were higher with severe but not mild PIVH.LIMITATIONS: Only observational studies were included. Fifteen of 21 included studies had a moderate-high risk of bias.CONCLUSIONS: Mild and severe PIVH are associated with progressively higher odds of death or moderatesevere NDI compared with no PIVH, but no studies adjusted for confounders. Among survivors, mild PIVH was associated with higher odds of moderate-severe NDI compared with no PIVH.

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“…Currently, there are studies that focus on the developmental and neuropsychological outcomes in preschool age. However, the results are thought to be unreliable [29][30][31][32]. There are also studies that concentrate on the outcome at school age; however they focus mainly on IQ [29].…”

Section: Introductionmentioning

confidence: 99%

Will electronic integrated text, visual and audio questionnaire be a better tool to evaluate the health status of paediatric hydrocephalus patients?

Tan¹,

Caird²,

Cooper³

2017

Ment Health Addict Res

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Neurodevelopmental Outcome of Extremely Low Birth Weight Infants With Posthemorrhagic Hydrocephalus Requiring Shunt Insertion

Cited by 274 publications

References 38 publications

Intraventricular Hemorrhage and Developmental Outcomes at 24Months of Age in Extremely Preterm Infants

Intraventricular Hemorrhage and Developmental Outcomes at 24Months of Age in Extremely Preterm Infants

Periventricular/Intraventricular Hemorrhage and Neurodevelopmental Outcomes: A Meta-analysis

Will electronic integrated text, visual and audio questionnaire be a better tool to evaluate the health status of paediatric hydrocephalus patients?

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