Neurocranial suture autotransplantation and periosteal dura stripping to provide a passive growth site in craniosynostosis – a case report

Application of Laser Capture Microdissection to Craniofacial Biology: Characterization of Anatomically Relevant Gene Expression in Normal and Craniosynostotic Rabbit Sutures

“…Recent studies further suggest that the dura mater is the primary source of paracrine signals that determine suture fate (Greenwald et al, 2000). Suture transplantation studies in a rabbit model for nonsyndromic familial CS support a role for the dura mater in the pathological suture fusion and are consistent with anecdotal evidence obtained in CS patients (Mooney et al, 2001; Mommaerts and Staels, 2003). The fibroblast growth factor (FGF) and transforming growth factor β (TGFβ) signaling pathways have been implicated in suture biology, and mutations affecting these pathways have been linked to a wide range of CS syndromes.…”