Neurocognition in Schizophrenia

Kalkstein, Solomon; Hurford, Irene; Gur, Ruben C.

doi:10.1007/7854_2010_42

Cited by 160 publications

(111 citation statements)

References 78 publications

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“…Schizophrenia is associated with marked deficits on a wide range of cognitive measures, including those assessing social cognitive ability (Bilder, 2009;Gur, et al, 2007;Kalkstein, Hurford, & Gur, 2010;Nuechterlein, et al, 2004). Theory of mind (ToM), an aspect of social cognition, refers to the cognitive ability of inferring agency, intentions, and beliefs that oneself and others hold.…”

Section: Introductionmentioning

confidence: 99%

Mentalizing in schizophrenia: A multivariate functional MRI study

et al. 2016

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Section: Introductionmentioning

confidence: 99%

Mentalizing in schizophrenia: A multivariate functional MRI study

et al. 2016

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“…En comparaison, un plus petit nombre d'études se sont intéressées aux plaintes cognitives subjectives, en dépit du fait que la documentation clinique a montré que 70 à 75 % des personnes atteintes de la schizophrénie ont des déficits cognitifs significatifs (Kalkstein et al, 2010). Ces déficits se manifestent dans les domaines de l'attention, de la résolution de problèmes, de la vitesse de traitement de l'information, de la mémoire épisodique (verbale et visuelle), de la mémoire de travail , de même que de la cognition sociale (Schmidt et al, 2011).…”

Section: Introductionunclassified

La conscience des déficits neurocognitifs dans la schizophrénie : une méta-analyse

Potvin

Pelletier

Stip

2014

smq

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Contexte La schizophrénie est un trouble allant de pair avec un manque d’autocritique par rapport aux délires et aux hallucinations. En contrepartie, on en sait beaucoup moins en ce qui concerne la conscience des patients par rapport à leurs déficits cognitifs, qui sont des symptômes clés de ce trouble psychiatrique. Afin de faire la synthèse de l’état de la connaissance à ce sujet, nous avons effectué une méta-analyse de 22 études comprenant 1609 patients. Les analyses ont révélé que les patients rapportent davantage de plaintes subjectives que les sujets sains. La corrélation entre la cognition subjective et objective s’est avérée faible toutefois. Les études utilisant la Scale to Investigate Cognition in Schizophrenia ont produit des corrélations plus fortes que celles utilisant d’autres échelles de plaintes subjectives. La relation entre la cognition subjective et les symptômes dépressifs s’est avérée comparable à la relation entre la cognition subjective et la cognition objective. Enfin, une relation faible a été observée entre la cognition subjective et l’autocritique par rapport aux symptômes positifs. Les résultats de la présente méta-analyse montrent que les patients atteints de la schizophrénie se plaignent de déficits cognitifs, mais qu’ils n’ont pas une représentation claire de la nature de ceux-ci, ce qui confirme l’existence de déficits méta-cognitifs dans la schizophrénie.

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“…Deficits vary among individuals, but often affect multiple cognitive domains, such as attention, executive function, memory, social cognition, and language. 3,4 Although antipsychotic drugs can improve many symptoms of this disease, treatment has little effect on alleviating cognitive impairment. [5][6][7] Since cognitive function is a strong predictor of functional outcomes, 8 it is critical to explore new strategies to attenuate this impairment.…”

Section: Introductionmentioning

confidence: 99%

The relationship between moderate-to-vigorous physical activity and executive function among individuals with schizophrenia: differences by illness duration

Grassmann

Subramaniapillai

Duncan

et al. 2017

Rev. Bras. Psiquiatr.

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Objective: Schizophrenia is a chronic mental illness characterized by positive and negative symptoms. Cognitive impairment continues to be a core and consistent deficit. Previous studies have shown that physical activity (PA) is positively associated with cognitive performance. Thus, it may play a supportive role in mitigating cognitive impairments among individuals with schizophrenia. The aim of this study was to analyze the relationship between moderate-to-vigorous physical activity (MVPA) and executive function among adults with schizophrenia. Methods: The weekly amount of MVPA (assessed using accelerometers) and executive function (as per Brief Neurocognitive Assessment for Schizophrenia) of 78 adults with schizophrenia (mean [SD] age 42.4 [11.4] years; illness duration 17.0 [11.0] years; 58.2% male) were assessed in this crosssectional study. Pearson correlations were calculated, followed by a linear regression. Participants were first analyzed together and then dichotomized on the basis of illness duration. Results: There was no significant association between MVPA and executive function, independent of the duration of illness. For individuals with o 15 years of illness, there was a significant association between weekly MVPA and working memory performance. Conclusion: PA appears to be associated with executive function in some, but not all, individuals with schizophrenia.

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Neurocognition in Schizophrenia

Cited by 160 publications

References 78 publications

Mentalizing in schizophrenia: A multivariate functional MRI study

Mentalizing in schizophrenia: A multivariate functional MRI study

La conscience des déficits neurocognitifs dans la schizophrénie : une méta-analyse

The relationship between moderate-to-vigorous physical activity and executive function among individuals with schizophrenia: differences by illness duration

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