Neural correlates of heart rate variability during emotion

Lane, Richard D.; McRae, Kateri; Reiman, Eric M.; Chen, Kewei; Ahern, Geoffrey L.; Thayer, Julian F.

doi:10.1016/j.neuroimage.2008.07.056

Cited by 594 publications

(482 citation statements)

References 68 publications

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“…The cerebellum is certainly involved in physiological regulation as a component of the central autonomic network (Spyer, 1999) contributing to the control of cardiovascular responses through its connections with the hypothalamus (Critchley, Corfield, Chandler, Mathias, & Dolan, 2000). Accordingly, covariation is observed between HRV and the cerebellum (Critchley et al 2003;Gianaros, Van Der Veen, & Jennings, 2004;Lane et al, 2009;Napadow et al, 2008).…”

Section: Discussionmentioning

confidence: 99%

Neurobiological substrates of cognitive rigidity and autonomic inflexibility in generalized anxiety disorder

Ottaviani

Watson

Meeten

et al. 2016

Biological Psychology

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Neurobiological substrates of cognitive rigidity and autonomic inflexibility in generalized anxiety disorder.Biological Psychology http://dx.doi.org/10. 1016/j.biopsycho.2016.06.009 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.  Trait worry was inversely related with prefrontal deactivation to target detection. HRV predicted neural activation changes produced by attentional focus switching. A worry induction increased pre-to post-target deactivation of default mode areas. The induction reduced behavioural and neurobiological differences between groups. AbstractGeneralized anxiety disorder (GAD) is characterized by difficulties in inhibiting both perseverative thoughts (worry and rumination) and autonomic arousal. We investigated the neurobiological substrates of such abnormal inhibitory processes, hypothesizing aberrant functional coupling within 'default mode' (DMN) and autonomic brain networks. Functional imaging and heart rate variability (HRV) data were acquired from GAD patients and controls during performance of three tracking tasks interspersed with a perseverative cognition (PC) induction. After detection of infrequent target stimuli, activity within putative DMN hubs was suppressed, consistent with a redirection of attentional resources from internal to external focus. This magnitude of activity change was attenuated in patients and individuals with higher trait PC, but was predicted by individual differences in HRV. Following the induction of PC in controls, this pattern of neural reactivity became closer to that of GAD patients. Results support, at a neural level, the association between cognitive inflexibility and autonomic rigidity.

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Section: Discussionmentioning

confidence: 99%

Neurobiological substrates of cognitive rigidity and autonomic inflexibility in generalized anxiety disorder

Ottaviani

Watson

Meeten

et al. 2016

Biological Psychology

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“…For example, across several emotion-induction tasks, Lane et al (2009) found that RSA correlated with cerebral blood flow in both the medial PFC and the anterior cingulate cortex. As hypothesized, emotion induction reduced both RSA and blood flow in these regions.…”

Section: Emotion Dysregulation and Youth Psychopathologymentioning

confidence: 99%

Future Directions in Emotion Dysregulation and Youth Psychopathology

Beauchaine

2015

Journal of Clinical Child & Adolescent Psychology

307

328

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“…Over the past few years, several neuroimaging and pharmacological studies have provided evidence that vagally mediated HRV is related to the inhibitory neural circuits that play an important role in selfregulation (Ahern et al, 2001;Lane et al, 2009). High vagally mediated resting HRV (henceforth referred to as high HRV) is associated with highly functional prefrontal inhibitory control over subcortical structures, which allows organisms to make situationally adaptive responses, such as distinguishing between safety and threat (Thayer & Lane, 2000;Thayer et al, 2009).…”

Section: The Neurovisceral Integration Model and Heart Rate Variabilitymentioning

confidence: 99%

Cardiac vagal tone predicts attentional engagement to and disengagement from fearful faces.

Park

Bavel

Vasey

et al. 2013

Emotion

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The current research examines individual differences in flexible emotional attention. In two experiments, we investigated the relationship between individual differences in cardiac vagal tone and top-down and bottom-up processes associated with emotional attention. To help determine the role of cortical and subcortical mechanisms underlying top-down and bottom-up emotional attention, fearful faces at broad, high, and low spatial frequency were presented as cues that triggered either exogenous or endogenous orienting. Participants with lower heart rate variability (HRV) exhibited faster attentional engagement to low-spatial-frequency fearful faces at short stimulus-onset asynchronies, but showed delayed attentional disengagement from high-spatial-frequency fearful faces at long stimulus-onset asynchronies in contrast to participants with higher HRV. This research suggests that cardiac vagal tone is associated with more adaptive top-down and bottom-up modulation of emotional attention. Implications for various affective disorders, including depression, anxiety disorders, and posttraumatic stress disorder, are discussed.

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Neural correlates of heart rate variability during emotion

Cited by 594 publications

References 68 publications

Neurobiological substrates of cognitive rigidity and autonomic inflexibility in generalized anxiety disorder

Neurobiological substrates of cognitive rigidity and autonomic inflexibility in generalized anxiety disorder

Future Directions in Emotion Dysregulation and Youth Psychopathology

Cardiac vagal tone predicts attentional engagement to and disengagement from fearful faces.

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