Neue (und alte) Aspekte der retroperitonealen Fibrose

Brandt, Alexander Sascha; Dreger, Nici Markus; Müller, Elisabeth; Kukuk, S.; Roth, Stephan

doi:10.1007/s00120-017-0428-y

Cited by 4 publications

(5 citation statements)

References 55 publications

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“…Malignant RF is refractory to pharmacologic treatment with immunosuppressants. Therefore, the focus should be on the diagnosis and treatment of the underlying neoplasm (17). Because recognition of a neoplastic cause alters the therapeutic approach, management algorithms for the diagnosis of secondary RF have been proposed, emphasizing the need for PET to detect active fibrosis or cancer and to guide biopsy (18,19).…”

Section: Discussionmentioning

confidence: 99%

Urothelial carcinoma masquerading as retroperitoneal fibrosis: A case report

Luengo,

Salmerón,

Medina

et al. 2024

Oncol Lett

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Retroperitoneal fibrosis, a rare and often idiopathic condition, poses significant diagnostic challenges. While most cases are considered idiopathic or immune-mediated, a small but important proportion are associated with malignant neoplasms, with implications for prognosis and management. The present study describes the case of a 69-year-old man who presented to the emergency department of the Virgen de las Nieves University Hospital (Granada, Spain), with a 2-week history of epigastric pain, vomiting and altered bowel habits. Laboratory investigations revealed previously undiagnosed renal insufficiency. An abdominal computed tomography (CT) scan showed extensive diffuse retroperitoneal infiltration extending from the periduodenal region to the pubic bone, resulting in gastric dilatation and hydronephrosis. A CT-guided retroperitoneal biopsy was performed and pathology confirmed the presence of urothelial carcinoma. This diagnosis led to the initiation of a chemotherapy regimen consisting of carboplatin and gemcitabine specifically designed for urothelial carcinoma. A follow-up 18F-FDG PET scan performed 6 months later showed a partial functional response. This case illustrates a rare presentation of urothelial carcinoma masked by extensive retroperitoneal fibrosis, and highlights the importance of accurate diagnosis in reducing tumor burden and improving the clinical status of patients.

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Section: Discussionmentioning

confidence: 99%

Urothelial carcinoma masquerading as retroperitoneal fibrosis: A case report

Luengo,

Salmerón,

Medina

et al. 2024

Oncol Lett

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“…Die radiologische Bildgebung besitzt eine zentrale Rolle und stellt den Goldstandard in der Diagnostik und Verlaufskontrolle der RPF dar, da sie entscheidet, ob z. B. Doppel-J-Schienen entfernt werden können oder eine Medikation pausiert wird, während der Stellenwert vieler Laborparameter als Therapiemonitoring weiterhin unklar bleibt [11,22].…”

Section: Bildmorphologische Merkmaleunclassified

“…Dennoch kommt es bei einem Teil der Patienten (ca. 18 %) im Langzeitverlauf zu einer Atrophie des vormals betroffenen Organs [11].…”

Section: Therapieunclassified

“…Medikamentös steht die Immunsuppression mittels verschiedener Alternativen (Kortison, Tamoxifen, Infliximab, Rituximab und Tocilizumab) im Vordergrund [11,[37][38][39][40] rung aus dem Retroperitoneum in das Omentumfett, alternativ offen-chirurgisch, laparoskopisch oder roboterassistiert. Möglicherweise müssen dabei, je nach Grad der Fibroseschäden, Teile der Harnleiter entfernt und reanastomosiert oder die kompletten Harnleiter durch Ileum oder Kolon ersetzt werden [6,11].…”

Section: Therapieunclassified

“…Im Fokus sollten daher die Diagnostik, z. B. mittels Biopsie, und Behandlung der malignen Grunderkrankung stehen[11].…”

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Retroperitoneal Fibrosis and its Differential Diagnoses: The Role of Radiological Imaging

Peisen

Thaiss

Ekert

et al. 2020

Rofo

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Background Retroperitoneal fibrosis is a rare disease with an incidence of 0–1/100 000 inhabitants per year and is associated with chronic inflammatory fibrosis of the retroperitoneum and the abdominal aorta. This article sheds light on the role of radiological imaging in retroperitoneal fibrosis, names various differential diagnoses and provides an overview of drug and surgical treatment options. Methods A literature search for the keywords “retroperitoneal fibrosis” and “Ormond’s disease” was carried out in the PubMed database between January 1, 1995 and December 31, 2019 (n = 1806). Mainly original papers were selected, but also reviews, in English and German language, with a focus on publications in the last 10 years, without excluding older publications that the authors believe are relevant to the topic discussed in the review (n = 40). Results and Conclusion Ormond’s disease is a rare but important differential diagnosis for nonspecific back and flank pain. Imaging diagnostics using CT or MRI show a retroperitoneal mass, which must be differentiated from lymphoma, sarcoma, multiple myeloma and Erdheim-Chester disease. Patients have an excellent prognosis under adequate therapy. FDG-PET/CT or FDG-PET/MRT should be considered as potential modalities, as hybrid imaging can evaluate both the morphological changes and the inflammation. Key Points: Citation Format

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„Wir legten eine Harnleiterschiene ein …“

Moll

Leißner

Halling

2018

Urologe

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The use of eponyms has a long history in medicine. But it is a rare case that a term not associated with a procedure or an anatomical description has come into use. The terms "stent" and "splint" in German and English used as a verb and a noun are a typical example. The coronary stent was named after Charles Thomas Stent (1807-1885). Charles Theodore Dotter (1920-1985) was the one who introduced the eponym into the literature of angiography in 1983. The change in urology occurred after an article of Willard Goodwin especially in the English literature but did not come into constant use in the German language.

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Neue (und alte) Aspekte der retroperitonealen Fibrose

Cited by 4 publications

References 55 publications

Urothelial carcinoma masquerading as retroperitoneal fibrosis: A case report

Urothelial carcinoma masquerading as retroperitoneal fibrosis: A case report

Retroperitoneal Fibrosis and its Differential Diagnoses: The Role of Radiological Imaging

„Wir legten eine Harnleiterschiene ein …“

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