Climate change adds pressure to the international community to work cooperatively, find ways to govern technologies and expert knowledge, develop better policies, and mobilise resources, tools, and practices to deal with potential consequences and impacts. The institutional drivers underpinning current knowledge applications in globally connected spaces of sustainable development practice are increasingly complex, intertwined, and empirically understudied. In this context, this PhD thesis aims to advance our empirical understanding of why and how formal cooperation networks form, negotiate, mobilise and utilise particular technologies and expert knowledge and attempt to steer visions and pathways for change. This research combines multi-sited ethnography with social network analysis and policy analysis and investigates formal contexts of global connection. This thesis examines practices of science and technology policy through technology-driven networks in multiple locations in Europe and Southeast Asia. In particular, this thesis analyses the processes and conditions through which tools (e.g. modelling technologies), practices (e.g. climate negotiations, technology transfer activities, risk management, and environmental planning), and ways of dealing with climate-related uncertainties are implemented in a global knowledge network articulated under the UN system. The