Nerve Tumors of the Upper Extremity

Strike, Sophia A.; Puhaindran, Mark E.

doi:10.1016/j.cps.2019.02.008

Cited by 24 publications

(22 citation statements)

References 14 publications

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“…Nerve tumors of the upper extremity include benign peripheral nerve sheath tumors (BPNSTs) and malignant peripheral nerve sheath tumors (MPNSTs). 6 BPNST can be broadly divided into neurofibromas and schwannomas. Neurofibromas are complex tumors composed of axonal processes, Schwann cells, fibroblasts, perineurial cells, and mast cells.…”

Section: Discussionmentioning

confidence: 99%

Diffuse Type Neurofibroma of the Forearm

Lahham

Aljassem

Omari

et al. 2022

Plastic and Reconstructive Surgery - Global Open

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Summary: Nerve sheath tumors comprise 5% of soft tissue masses of the upper limb in adults. Neurofibromas are divided into three types: localized, diffuse, and plexi- form. The diffuse type is rare and is typically found in the head and neck region. We present a rare case of diffuse type neurofibroma found in the forearm, presented to our clinic as a slowly enlarging mass of the left forearm of 3 years duration. The lesion was suspicious in the magnetic resonance imaging, and biopsy revealed diffuse type neurofibroma. We opted for total excision of the lesion that was found to be not possible due to involvement of the major nerves. The final pathology report showed no malignancy. Nerve tumors of the upper limb can be either benign or malignant. Neurofibroma associated with neurofibromatosis has malignant potential. The diffuse type is rare, and it most commonly occurs in the head and neck region. It has a low malignant transformation rate. Magnetic resonance imaging is the diagnostic modality of choice; however, it can be inconclusive. Biopsy should be taken to confirm the diagnosis and plan for management. Our case was managed by near total excision in order to preserve the major forearm nerves because of high clinical suspicion.

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Section: Discussionmentioning

confidence: 99%

Diffuse Type Neurofibroma of the Forearm

Lahham

Aljassem

Omari

et al. 2022

Plastic and Reconstructive Surgery - Global Open

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“…A schwannoma is a tumor originating from Schwann cells of the nerve sheath ( 14 ). It can affect all body parts, but it is most localized in the head and neck, and in the flexor aspect of the limbs, it can also localize, where many nerves are distributed ( 15 , 16 ). Chest walls with adjacent axillary schwannomas are extremely uncommon.…”

Section: Discussionmentioning

confidence: 99%

Case Report: Upper limb dysfunction may be caused by chest wall mass excision: An enlightenment from a special case

Yuan²,

Xiong

et al. 2022

Front. Oncol.

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Of all the thoracic surgical procedures, chest wall surgery is probably the lowest-risk type. In fact, it is not so. Clinical work also often has the trap of chest wall surgery. An operation to remove a mass in the axilla may result in upper limb disability on the affected side. Here, we report the case of a 47-year-old female patient with a left chest wall adjacent axillary mass, which was considered an abnormal structural lymph node on color ultrasound examination and chest CT. Otherwise, she felt no discomfort. The left upper limb moved freely without being affected by the mass. A routine resection of the tumor was performed after the preoperative examination was completed. After the operation, the incision recovered well. However, the day after the surgery, she developed numbness and pain in her left little finger and ring finger, pain that often kept her from sleeping. The mass was confirmed to be a schwannoma with cystic degeneration by pathology slicing after the operation. By this time, doctors were alerted to the fact that the removal of the chest wall mass had nearly disabled the left upper limb of the patient, which was a great warning to the thoracic surgeon. In this case report, we hope that all surgeons will be cautious and careful and will not trust the imaging diagnosis too much. It is also hoped that the patient understands that some procedures may lead to unexpected complications.

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“…Schwannomas are typically eccentrically located in relation to the parent nerve, with the nerve fibers draped over the tumor. In contrast, neurofibromas arise more centrally and expand the parent nerve [9] . When circumferential growth of a peripheral nerve sheath tumor is restricted by a bony canal or foramen, as occurs with tumors arising from spinal nerves at the neural foramina, the lesion may assume a dumbbell-shaped morphology [ 10 , 11 ].…”

Section: Introductionmentioning

confidence: 97%

Partially intraosseous schwannoma of the distal humerus with increased enhancement after biopsy: Radiologic-pathologic correlation

Hansra

Brown

Kang

et al. 2022

Radiology Case Reports

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Intraosseous schwannomas are rare benign tumors that most often occur at the mandible or sacrum. We present an unusual case of a bilobed schwannoma of the distal humerus with both intraosseous and extraosseous components. The extraosseous component was non-enhancing on initial MRI and enhanced on a subsequent MRI obtained after biopsy. We hypothesize that this change was attributable to decreased intra-tumoral pressure secondary to biopsy-related disruption of the tumor capsule.

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Nerve Tumors of the Upper Extremity

Cited by 24 publications

References 14 publications

Diffuse Type Neurofibroma of the Forearm

Diffuse Type Neurofibroma of the Forearm

Case Report: Upper limb dysfunction may be caused by chest wall mass excision: An enlightenment from a special case

Partially intraosseous schwannoma of the distal humerus with increased enhancement after biopsy: Radiologic-pathologic correlation

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