Nephrotoxicity of N-(3-bromophenyl)-2-hydroxysuccinimide: role of halogen groups in the nephrotoxic potential of N-(halophenyl)succinimides

Identification and Quantification of Dimethachlon Degradation Products in Soils and Their Effects on Soil Enzyme Activities

“…7 Some European nations have outlawed the use of dimethachlon because some researchers claimed it could be nephrotoxic. 8 Because of its promising antifungal activity in crops like rapeseed and rice, dimethachlon is still widely used in developing nations. 9 Agricultural soil may contain a variety of pesticide residues because of the ongoing application of pesticides in the field.…”

“…Histidine kinase (HK) and mitogen-activated protein kinase (MAPK) comprise the signaling pathway that is the major target of this substance’s mechanism of action . Some European nations have outlawed the use of dimethachlon because some researchers claimed it could be nephrotoxic . Because of its promising antifungal activity in crops like rapeseed and rice, dimethachlon is still widely used in developing nations …”

Synthesis of Pyridine and Phenyl Succinimides by Green Pathway and Their Antimicrobial Assay

“…Their bio-transformations of racemic and chiral forms are susceptible on fungi [2]. They are significant regioselective [3] and stereo-selective [4], and nephrotoxicity NDHS formation [5]. Various succinimide derivatives exhibit good anticonvulsants [6][7], 5-HT1A or 5-HT7 receptors affinity [8], antimicrobial activities [9][10][11], in vitro bovine acetyl cholinesterase inhibitors [12], Mitochondrial and Cytotoxicity effect [13] and plant growth regulator [14], anti-mutagenic and anti-epileptic activities [15] so on.…”