Nephrotoxicity of hydroalcoholic extract ofTeucrium polium in Wistar rats

Antimicrobial Activity and Phytochemical Screening of Aloe vera (Aloe barbadensis Miller)

“…It is revealed that it has conspicuous pharmacological activities such as antibacterial (Subramanian et al, 2006;Arunkumar and Muthuselvam, 2009;Saritha et al, 2010;Fani and Kohanteb, 2012;Nejatzadeh-Barandozi, 2013), antifungal (Bajwa et al, 2007;Rosca-Casian et al, 2007;Khaing, 2011;Sitara et al, 2011), antiviral (Zandi et al, 2007), antioxidant (Baradaran et al, 2013;Ray et al, 2013;Kang et al, 2014), cytotoxic (Jose et al, 2014;Shalabi et al, 2015), antidiabetic (Tanaka et al, 2006;Choudhary et al, 2014;Suleyman et al, 2014), anti-inflammatory (Vijayalakshmi et al, 2012;Bhattacharjee et al, 2014), antitumor (El-Shemy et al, 2010;Srihari et al, 2015), nephroprotective (Iftikhar et al, 2015;Virani et al, 2016), antiulcer (Borra et al, 2011) and anti-aging effects which can be used as a moisturizing agent to cure cardiovascular diseases as well as to enhance the immune system (Chatterjee et al, 2013). It is used as an herbal medicine since long time which contains more than 100 bioactive constituents.…”

Identification of medicinal plants effective in infectious diseases in Urmia, northwest of Iran

“…They have demonstrated promising effects in a wide variety of diseases such as cancer [16,17] , diabetes [18,19] , atherosclerosis and cardiovascular diseases [20][21][22][23] , learning and cognitive complications [24][25][26] , and wounds [27][28][29] . Furthermore, medicinal herbs are also effective in prevention and treatment of the toxicity induced by other drugs or toxins [30][31][32][33][34][35][36][37] . Medicinal plants are a rich source of bioactive substances, antioxidants, flavonoids, and phenolic substances and have multiple health effects [12,[38][39][40][41][42][43][44][45][46][47][48][49][50][51][52][53][54][55].…”

Comment on: Preventive effect of Teucrium polium on learning and memory deficits in diabetic rats

“…We would like to point out a few comments about this paper. To test the possible renal toxicity of hydroalcoholic extract of Teucrium polium , we recently studied 100 male Wistar rats [2] divided into 10 groups of 10 each. Five groups were injected intraperitoneally (IP) with 50, 100, 150, and 200 mg/kg extracts and normal saline for 28 days and killed to examine the probable kidney damage.…”

“…However, kidney injury, including degeneration, destruction, and vacuolization [3–5] appeared 28 days after drug cessation. We concluded that Teucrium polium may be associated with kidney tubular injury and that this herbal medicine should be used with caution [2]. It is well known that herbal remedies have an important role in the recovery of some disease [6–9]; however, some medicinal plants can cause renal injury.…”