Nephroprotective effect of <i>Emblica officinalis</i> fruit extract against malachite green toxicity in piscine model: Ultrastructure and oxidative stress study

Sinha, Reshma; Jindal, Ravul; Faggio, Caterina

doi:10.1002/jemt.23747

Cited by 18 publications

(5 citation statements)

References 39 publications

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“…Natural immunostimulants are appropriate for aquaculture to minimize chemotherapies' application ( Dawood, 2021 , Lieke et al, 2020 ). Indeed, phytogenic derived substances are approved as effective, friendly alternatives in aquaculture ( Sinha et al, 2021 , Vazirzadeh et al, 2020 , Zhu, 2020 ). Isatis root powder is extracted initially from Isatis indigotica (Cruciferae) and cultured in several Asian, middle east, and European countries ( Speranza et al, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

Isatis phytogenic relieved atrazine induced growth retardation, hepato-renal dysfunction, and oxidative stress in Nile tilapia

Ali

Soliman

Gewaily

et al. 2022

Saudi Journal of Biological Sciences

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The influence of herbicides causes health and economic loss, which requires innovative solutions to sustain the aquaculture industry. In this regard, dietary isatis is included in Nile tilapia diets to relieve atrazine (ATZ)-induced growth retardation, hepato-renal dysfunction, and oxidative stress. The first and second groups offered the control diet (control), while the third and fourth groups offered the isatis supplemented diet (1%). Meantime, half of the water was replaced and mixed with ATZ (1.39 mg/L) in the second and fourth groups for 30 days. The group of fish delivered isatis had significantly enhanced FBW, WG, and SGR, while fish intoxicated with ATZ had meaningfully impaired growth behavior ( p < 0.05). Further, the FCR was improved by isatis, and ATZ resulted in the worst FCR among the groups. Interestingly fish fed isatis and exposed with ATZ (88.89%) had a higher survival rate than fish exposed with ATZ without isatis feeding, and both are lower than the control (97.78%) ( p < 0.05). The histological structure in the isatis-treated groups showed distinguished enhancement and branching of the intestinal villi. The intestine of ATZ–treated fish revealed damage and inflammatory cell infiltration in the intestinal mucosa with separation of lining epithelium. Generally, fish fed isatis and intoxicated with ATZ had lower uric acid, urea, creatinine, ALT, and AST and higher total protein, globulin, and albumin than fish exposed with ATZ without feeding with isatis ( p < 0.05). Markedly, fish-fed isatis had the highest SOD, CAT, GPx, and the lowest MDA level compared to the other groups ( p < 0.05). Meanwhile, fish exposed with ATZ had the worst SOD, CAT, GPx, and the highest MDA level compared to the other groups ( p < 0.05). In summary, dietary isatis relieved ATZ induced growth retardation, hepato-renal dysfunction, and oxidative stress in Nile tilapia.

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Section: Introductionmentioning

confidence: 99%

Isatis phytogenic relieved atrazine induced growth retardation, hepato-renal dysfunction, and oxidative stress in Nile tilapia

Ali

Soliman

Gewaily

et al. 2022

Saudi Journal of Biological Sciences

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“…Therefore, naturally derived biological compounds have gained much attention to overcome the abovementioned challenges. [81][82][83][84][85][86] In particular, many plants and mushroom-derived compounds have been used as a natural immunostimulant in aquaculture and animal nutrition. 87,88…”

Section: Highlightsmentioning

confidence: 99%

“…However, this could lead to the biomagnification of antibiotics from cultivable organisms to humans through the food chain. Therefore, naturally derived biological compounds have gained much attention to overcome the abovementioned challenges 81–86 . In particular, many plants and mushroom‐derived compounds have been used as a natural immunostimulant in aquaculture and animal nutrition 87,88 …”

Section: Impacts Of Antibiotics In Aquaculturementioning

confidence: 99%

The potential role of medicinal mushrooms as prebiotics in aquaculture: A review

Mohan¹,

Rajan

Thirunavukkarasu

et al. 2022

Reviews in Aquaculture

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Aquaculture industry is one of the major food‐producing sectors in the world that provide nutritional food security for mankind. Fish and crustacean farmers are facing various challenges in treating the rapid spread of infectious diseases in recent times. Numerous strategies, including antibiotics, disinfectants, and other antimicrobial agents, have been applied to protect the cultivable aquatic animals from infectious diseases. These applications lead to the development of antimicrobial resistance, toxicity, and the accumulation of antibiotic residues in cells and organelles of the cultivable edible organisms and the environment. The use of naturally derived compounds, polysaccharides, and functional metabolites has gained immense attention among aquaculturists. Mushrooms and their nutraceutical components have been widely used in various sectors, including food, pharmaceutical, poultry, and aquaculture industries, for their non‐toxic and eco‐friendly properties. To date, there are several reports available on edible and medicinal mushrooms as a dietary ingredient for fish and decapod crustacean culture. The mushroom products such as mycelia, stalk, dry powder, polysaccharides, and extracts have been utilized in aquaculture as growth promoters and immunostimulants, improving the digestive enzyme activity, antimicrobials, and improving the health status of cultivable aquatic animals. This present review elucidates the effectiveness of mushrooms and mushroom‐derived compounds as prebiotics in aquaculture. The challenges and future perspectives of mushroom‐derived bioactive molecules have been discussed in this review.

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“…Following reports of pesticides impacting and shaping the occurrence of global freshwater biodiversity, various criteria based on ecologically relevant risk estimates have been explored to protect aquatic life from pesticide stress [9,14,29,[35][36][37][38][39][40]. Furthermore, the use of integrated biomarker endpoints in evaluating and visualizing chemical exposure effects on aquatic organisms is still not widely applied [41].…”

Section: Introductionmentioning

confidence: 99%

Chronic Effects of Diazinon® Exposures Using Integrated Biomarker Responses in Freshwater Walking Catfish, Clarias batrachus

Saha¹,

Chukwuka²,

Mukherjee

et al. 2021

Applied Sciences

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Diazinon exposures have been linked to the onset of toxic pathways and adverse outcomes in aquatic species, but the ecological implications on model species are not widely emphasized. The objective of this study was to determine how the organophosphate pesticide diazinon affected hematological (hemoglobin, total red blood count, total white blood count, and mean corpuscular hemoglobin), growth (condition factor, hepatosomatic index, specific growth rate), biochemical (total serum glucose, total serum protein), and endocrine (growth hormone, tri-iodothyronine, and thyroxine) parameters in Clarias batrachus after chronic exposure. Diazinon was administered at predefined exposure doses (0.64 and 1.28 mg/L) and monitored at 15, 30, and 45 days into the investigation. Observation for most biomarkers revealed patterns of decreasing values with increasing toxicant concentration and exposure duration. Correlation analysis highlighted a significant inverse relationship between variables (mean corpuscular hemoglobin, condition factor, specific growth rate, tri-iodothyronine, thyroxine, and total serum protein) and elevated chronic diazinon exposure concentrations. The integrated indices (IBR and BRI) indexes were used to provide visual and understandable depictions of toxicity effects and emphasized the relativity of biomarkers in terms of sensitivity and magnitude or severity of responses under graded toxicant exposures. The significant damage reflected by evaluated parameters in diazinon exposure groups compared to control portends risks to the health of local fish populations, including Clarias batrachus in aquatic systems adjacent to agrarian landscapes.

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Nephroprotective effect of Emblica officinalis fruit extract against malachite green toxicity in piscine model: Ultrastructure and oxidative stress study

Cited by 18 publications

References 39 publications

Isatis phytogenic relieved atrazine induced growth retardation, hepato-renal dysfunction, and oxidative stress in Nile tilapia

Isatis phytogenic relieved atrazine induced growth retardation, hepato-renal dysfunction, and oxidative stress in Nile tilapia

The potential role of medicinal mushrooms as prebiotics in aquaculture: A review

Chronic Effects of Diazinon® Exposures Using Integrated Biomarker Responses in Freshwater Walking Catfish, Clarias batrachus

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