Nephropathy: New aspects of mechanisms, diagnosis and therapy

Bradykinin—from snake poison to therapeutic options

“…Kinins are produced in several different tissues, such as vessels, lung, brain and kidney . In the kidney, bradykinin receptors B1 and B2 modulate renal sympathetic nerve activity and increase medullary blood flow . In general, kinins induce a decrease in systemic blood pressure through stimulating natriuresis and diuresis in the kidney.…”

D‐serine—A useful biomarker for renal injury?

“…Nephropathies are characterized as loss of kidney function due to renal disease or kidney damage. 4 Many publications, issued recently in Acta Physiologica, cover diverse areas of the extensive field of kidney research. Among these are studies about renal haemodynamics, [5][6][7] about potential prevention of acute kidney injury 8 or promising treatment of chronic kidney disease.…”

“…9,10 Investigations to understand, diagnose and treat renal diseases and renal damage are necessary and important for patients, society and public health care. 4 Moreover, biomarkers for fast and clear-cut detection of origin and location of renal damage still need to be established.…”

“…Nephropathies are characterized as loss of kidney function due to renal disease or kidney damage 4 . Many publications, issued recently in Acta Physiologica, cover diverse areas of the extensive field of kidney research.…”

“…Among these are studies about renal haemodynamics, 5‐7 about potential prevention of acute kidney injury 8 or promising treatment of chronic kidney disease 9,10 . Investigations to understand, diagnose and treat renal diseases and renal damage are necessary and important for patients, society and public health care 4 . Moreover, biomarkers for fast and clear‐cut detection of origin and location of renal damage still need to be established.…”