Neonatal Sepsis: past, present and future; a review article

Tripathi, Shalini; Malik, G. K.

doi:10.4314/ijmu.v5i2.56163

Cited by 44 publications

(45 citation statements)

References 40 publications

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“…Newer diagnostic tests including acute phase reactants like procalcitonin, fibronectin and neopterin, cell surface markers like neutrophil CD11b and CD64, granulocyte colony stimulating factor and cytokines like interleukins, tumour necrosis factor α and chemokine's are emerging. 15 Molecular methods like PCR have shown promise. 15,19 It becomes imperative to test the validity of our existing diagnostic tools in this changing scenario.…”

Section: Resultsmentioning

confidence: 99%

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Changing role of neonatal sepsis markers in the era of BacT/Alert: is there a need to devise a new septic screen

Ahmad

Ahmed

Abrar

et al. 2016

Int J Contemp Pediatr

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Section: Resultsmentioning

confidence: 99%

“…15 Molecular methods like PCR have shown promise. 15,19 It becomes imperative to test the validity of our existing diagnostic tools in this changing scenario. WBC count, ANC, platelet count and CRP are included in many septic screens and their diagnostic value was checked in our study.…”

Section: Resultsmentioning

confidence: 99%

Changing role of neonatal sepsis markers in the era of BacT/Alert: is there a need to devise a new septic screen

Ahmad

Ahmed

Abrar

et al. 2016

Int J Contemp Pediatr

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“…These findings may often mixable with noninfective causes because they are not specific for EOS [3]. Verification of EOS is also important to avoid overtreatment of non-septic infants with antimicrobial agents which may cause to colonization with drug-resistant microorganisms and superinfection with other pathogens.…”

Section: Introductionmentioning

confidence: 99%

The utility of maternal mean platelet volume levels for early onset neonatal sepsis prediction of term infants

Çekmez

Güleçoğlu²,

Özcan³

et al. 2017

Ginekol Pol

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Objectives: This study is aimed to evaluate the role of maternal mean platelet volume (MPV) levels for antenatal prediction marker of early onset neonatal sepsis in term infants born to mothers who have low infection risk. Material and methods:A total of 62 pregnant women who gave birth in our hospital and whose neonates were admitted to a third level Neonatal Intensive Care Unit due to confirmed neonatal sepsis between January 2010 and May 2016 were selected as a study group. Within the same period, 68 women who gave birth to healthy neonates were enrolled as a control group. We compared maternal MPV values which were evaluated before delivery. The receiver operating characteristic (ROC) curves were drawn to evaluate the values maternal MPV in the diagnosis of neonatal sepsis.Results: MPV levels were detected statistically higher in the study group than the control group (8.27 ± 1.85 vs. 8.98 ± 1.16) (p = 0.001). Conclusion:The maternal serum MPV level is a clinically useful, non-invasive and reliable marker in antenatal prediction of EOS.

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“…[3] Early diagnosis of neonatal sepsis is difficult as manifestations are ill-defined. [4] On the other hand, multidrug resistant (MDR) strains are emerging. [5] In this perspective, the purpose of the study is to evaluate the results of different diagnostic tests in the presence of risk factors and/or clinical picture.…”

Section: Introductionmentioning

confidence: 99%