Objectives: This study is aimed to evaluate the role of maternal mean platelet volume (MPV) levels for antenatal prediction marker of early onset neonatal sepsis in term infants born to mothers who have low infection risk. Material and methods:A total of 62 pregnant women who gave birth in our hospital and whose neonates were admitted to a third level Neonatal Intensive Care Unit due to confirmed neonatal sepsis between January 2010 and May 2016 were selected as a study group. Within the same period, 68 women who gave birth to healthy neonates were enrolled as a control group. We compared maternal MPV values which were evaluated before delivery. The receiver operating characteristic (ROC) curves were drawn to evaluate the values maternal MPV in the diagnosis of neonatal sepsis.Results: MPV levels were detected statistically higher in the study group than the control group (8.27 ± 1.85 vs. 8.98 ± 1.16) (p = 0.001). Conclusion:The maternal serum MPV level is a clinically useful, non-invasive and reliable marker in antenatal prediction of EOS.
Background:The aim of our study was to find out whether exercise of the pelvic muscles during vaginal delivery increases maternal and cord blood irisin levels.Methods:This prospective study included 20 patients who vaginally delivered their babies and 20 patients that underwent elective cesarean section. In the vaginal delivery group, delivery occured either spontaneously or by induction. In the other group, the patients were electively operated before uterine contractions started. We compared serum irisin levels of the two groups and cord blood irisin levels of the babies of these mothers.Results:There was no statistically significant difference in maternal serum irisin levels between the two groups (p>0.05). We also found no statistically significant difference in cord blood irisin levels (p>0.05). The positive correlation between maternal and cord blood irisin levels was found to be statistically significant (p<0.05). We also detected a significant positive correlation between maternal irisin levels and BMI in our study (p<0.05).Conclusions:Irisin is a challenging molecule. Although we did not find a significant difference in the irisin levels of women according to the method of delivery, we feel that further investigations are warranted.
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