Neonatal outcome in meconium stained amniotic fluid: a hospital based study

Singh, Gurmeet; Singh, Onkar; Thapar, Karuna

doi:10.18203/2349-3291.ijcp20170425

Cited by 9 publications

(10 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In our study, 14% of patients with MSAF had postdated pregnancies. This correlated with the study conducted by Rafia et al and Singh et al in which they had 13% and 12% postdated pregnancies, respectively [ 8 , 12 ].…”

Section: Discussionsupporting

confidence: 90%

Impact of Meconium-Stained Amniotic Fluid on Neonatal Outcome in a Tertiary Hospital

Parween¹,

Prasad²,

Poonam³

et al. 2022

Cureus

View full text Add to dashboard Cite

Objective The aim of this study was to determine the perinatal outcome of pregnant patients complicated with meconium-stained amniotic fluid (MSAF) compared with clear amniotic fluid. Methodology This prospective cross-sectional study was conducted in the Department of Obstetrics and Gynecology in collaboration with the Department of Pediatrics at Indira Gandhi Institute of Medical Sciences, Patna, India, from September 2016 to January 2018. A total of 200 patients were included in the study after taking their written consent. Out of these 200 patients, 100 patients had MSAF, and the other 100 patients with clear liquor were taken as controls after fulfilling the inclusion and exclusion criteria. These two groups of patients were compared regarding various maternal and neonatal parameters. These parameters were compared and tested statistically for significance. Results Among the 100 patients with MSAF, 20 patients had grade 1 meconium (X), 22 patients had grade 2 meconium (Y), and 58 patients had grade 3 meconium (Z). The majority of patients in the MSAF group were primigravida and more than 25 years of age. In addition, 47% of patients in the MSAF group had some associated high-risk factors and 50% of patients had non-reassuring fetal heart rate patterns, and among these, 39 patients had grade 3 MSAF (X). In the MSAF group, 49% of patients had undergone lower segment cesarean section (LSCS), whereas in the non-MSAF group, it was 37%. Also, 30% of babies in the MSAF group and 13% in the non-MSAF group had neonatal intensive care unit (NICU) admission; 22% of babies in the MSAF group and 12% of babies in the non-MSAF group had an adverse neonatal outcome. Meconium aspiration syndrome was present in 14% of the patients in the MSAF group, and among these, two babies had neonatal death and both had severe birth asphyxia. In the non-MSAF group, there was one neonatal death due to neonatal sepsis. However, after statistically analyzing the neonatal outcome in both the groups, there was no statistical difference between the two groups (p<0.001). Conclusion MSAF is associated with increased frequency of operative delivery, poor neonatal outcomes, and increased NICU admission. Management of labor with MSAF requires appropriate intrapartum care with continuous fetal heart rate monitoring, and this can reduce unnecessary cesarean sections in patients with MSAF.

show abstract

Section: Discussionsupporting

confidence: 90%

Impact of Meconium-Stained Amniotic Fluid on Neonatal Outcome in a Tertiary Hospital

Parween¹,

Prasad²,

Poonam³

et al. 2022

Cureus

View full text Add to dashboard Cite

show abstract

“…11 The study done by Gurmeet et al showed that 33% of the cases with MAS expired and 67% of cases with MAS were discharged, which is almost similar to the present study. 8 The number of discharged cases were more than expired cases in patients with MAS, which is similar to the present study. But all the expired cases in had severe MAS.…”

Section: Discussionsupporting

confidence: 92%

“…7 The study done by Singh G et al, showed that 76% of the neonates were more than 2.5 kg, which is higher than present study. 8 LSCS delivery was more in MSAF babies. The study done by Rokade J et al, showed that 111 patients (56%) delivered by L.S.C.S which is almost similar to present study.…”

Section: Discussionmentioning

confidence: 86%

Study of respiratory complications and outcome in meconium stained deliveries

Shukla

Swapna

2019

Int J Contemp Pediatr

View full text Add to dashboard Cite

Background: To study the development of respiratory complications in the form of meconium aspiration syndrome (MAS), persistent pulmonary hypertension of newborn (PPHN), pulmonary hemorrhage and pneumothorax in neonates born through meconium stained liquor.Methods: It was a prospective study conducted during the period of February to October 2018. All live babies associated with meconium stained liquor were included.Results: Total 606 neonates with meconium stained amniotic fluid (MSAF) were enrolled. Chance of meconium passage was more after 37wk of gestation, in birth weight >2.5 kg and in AGA babies. The rate of LSCS was higher in MSAF group. MAS developed in 28% cases, out of which 42.9% expired. PPHN developed in 6.9% cases, out of which 80% expired. 100% mortality was there in babies with pulmonary hemorrhage. Apgar scores <7 is significantly associated with the development of respiratory complications. 22.8% of vigorous babies and all non-vigorous babies developed respiratory complications showing statistical significance with P-value of <0.00001. Mortality in MSAF was 12%. All babies who expired had severe meconium aspiration syndrome. 83.9% of the patients stayed for <7 days in the hospital. All of the expiry except one occurred within 7 days of life due to development of respiratory complications.Conclusions: MSAF is associated with the development of respiratory complications and mortality in neonates. Non-vigorous babies and the babies with Apgar scores <7 at birth are more prone to developing respiratory complications. Most of the MSAF babies were discharged and mortality was more in patients with respiratory complications.

show abstract

“…Patil et al 30 reported meconium aspiration was the cause of death in around 4 cases and one died due to serve birth asphyxia with hypoxic-ischemic encephalopathy. Gurmeet Singh 31 found 16% mortality with MSAF.…”

Section: Discussionmentioning

confidence: 98%

Neonatal Outcome in Meconium Stained Amniotic Fluid (MSAF): A Study in a Neonatal High Dependency Unit (NHDU) of a Medical College Hospital

Ali¹,

Maruf²,

Naher³

et al. 2019

Mediscope

View full text Add to dashboard Cite

Background: Meconium-stained amniotic fluid (MSAF) is a potential sign of fetal hypoxia as well as a potential toxin if the fetus aspirates with a gasping breath in utero or when it takes its first breaths following birth. Objective: To evaluate the outcome of neonates with meconium-stained amniotic fluid (MSAF). Material and Methods: This prospective observational study was carried out in the department of pediatrics of Gazi medical college Hospital, Khulna during one calendar year from 01 July 2016 to 30 June 2017. Maternal risk factors for MSAF, modes of delivery of neonates were recorded. All neonates born with MSAF were included in this study: they were shifted to neonatal high dependency unit for observation and monitoring as per the pediatrician’s advice. Neonatal outcomes like birth asphyxia, neonatal jaundice, aspiration pneumonia, septicemia, meconium aspiration syndrome (MAS), hypoxic-ischemic encephalopathy (HIE) and death were observed and recorded. Result: A total of 157 babies were included during the study period. Modes of delivery of babies were: normal delivery 86(54.78%), caesarean section 48(30.57%) and instrumental delivery 23(14.65%). Maternal risk factors were postdated pregnancy 51(32.48%), previous caesarian section 20(12.74%), pregnancy-induced hypertension (PIH) 20(12.74%), premature rupture of membranes 18(11.46%), gestational diabetes mellitus (GDM) 17(10.83%), intrauterine growth retardation (IUGR) 14 (8.92%), cephalopelvic disproportion 9(5.73%) and anemia 8(5.10%). Outcome of babies were: 118(75.16%) babies were discharged without any complications, 10(6.37%) developed neonatal jaundice, 10(6.37%) meconium aspiration syndrome (MAS), 8(5.10%) birth asphyxia, 4(2.55%), aspiration pneumonia, 3(1.91%) hypoxic-ischemic encephalopathy (HIE), 2(1.27%) septicemia and 2(1.27%) baby died in early neonatal period. Mediscope Vol. 6, No. 2: Jul 2019, Page 65-71

show abstract

Neonatal outcome in meconium stained amniotic fluid: a hospital based study

Cited by 9 publications

References 15 publications

Impact of Meconium-Stained Amniotic Fluid on Neonatal Outcome in a Tertiary Hospital

Impact of Meconium-Stained Amniotic Fluid on Neonatal Outcome in a Tertiary Hospital

Study of respiratory complications and outcome in meconium stained deliveries

Neonatal Outcome in Meconium Stained Amniotic Fluid (MSAF): A Study in a Neonatal High Dependency Unit (NHDU) of a Medical College Hospital

Contact Info

Product

Resources

About