Neolignan and flavonoid glycosides in Juniperus communis var. depressa

Caffeic Acid Oligomers with Hyaluronidase Inhibitory Activity from <i>Clinopodium gracile</i>

“…The circular dichroism (CD) spectrum showed a negative Cotton effect at 225 nm, suggesting 7′S. [9][10][11] Based on this data, the structure of clinopodic acid J was elucidated as 1.…”

Three New Lignan Glycosides with IL-6 Inhibitory Activity from <i>Akebia quinata</i>

“…These results indicated that 1 had two phenylpropanoid units. 16,17) Significant HMBC correlations were also observed between H-7/C-5′ and H-8/C-4′. Therefore, it could be concluded that two phenylpropanoids formed a 7,8-dihydro-8-hydroxymethyl-7-phenyl-1′-benzofuranpropanol skeleton.…”

“…Therefore, it could be concluded that two phenylpropanoids formed a 7,8-dihydro-8-hydroxymethyl-7-phenyl-1′-benzofuranpropanol skeleton. 16,17) In the 1 H-1 H-correlation spectroscopy (COSY) spectrum, the oxymethine proton at δ H 5.52 showed coupling with H-8, in addition methylene protons at δ H 2.62 showed coupling with H-8′ and H-9′. The glycosidic linkage was identified at C-2′ by nuclear Overhauser enhancement spectroscopy (NOESY) experiment and HMBC correlations as shown in Fig.…”

“…2), and a comparison of the observed and reported NMR data. 8,16) In the NOESY spectrum, correlations between H-1″, assigned an α-orientation, and H-8, H-7 indicated that these are on the same side (α). These NOE correlations suggested the relative configuration at C-7 and C-8 as shown in 3.…”

A New Neolignan Glycoside from the Leaves of Acer truncatum

“…Significant HMBC correlations were also observed between H-7/C-4′ and H-8/C-5′. These spectral features indicated that 1 was a 7-aryl-8-hydroxymethyl-7,8-dihydrobenzofuranoid-type neolignan formed by two phenylpropanoid units [13][14][15][16][17]. The two methoxyl groups were located at C-3 and C-3′ and the β -glucopyranosyl group was connected at C-9′, based on the HMBC and ROESY correlations ( Figure 1).…”