Nematode (Ancylostoma) in the Cornea*

Nadbath, Rudolph P.; Lawlor, Peter P.

doi:10.1016/0002-9394(65)93754-2

Cited by 13 publications

(4 citation statements)

References 10 publications

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“…Thereafter some larvae may migrate to the lungs (WRIGHT & GOLD, 1946; KALMON, 1954) and also appear in the sputum (MUHLEISEN, 1953). Larvae of an unknown species of hookworm have been reported in the human cornea (BALDONE et al, 1964;NADBATH & LAWLOR, 1965). In experimental infections, A. caninum larvae migrate through the intestine, liver, lungs and ultimately the muscles and brain of mice after oral infection (BHOPALE & JOHRI, 1978) and this may suggest a possible risk of such infection to man (BHOPALE & JOHRI, 1978).…”

Section: Introductionmentioning

confidence: 99%

Efficacy of various anthelmintics against third-stage larvae of Ancylostoma caninum in the brain of mice

Bhopale

Bhatnagar

1988

J. Helminthol.

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In an experimental larval infection of Ancylostoma caninum in mice, the efficacy of various anthelmintics against the larvae migrated and established in the brain is reported for the first time. Albendazole and flubendazole were the most effective drugs. Thiabendazole, benacil, phenacizole, oxfendazole and mebendazole showed significant larvicidal activity. Tetramisole, levamisole, fenbendazole, Sch 18099, pyrantel pamoate, morantel tartrate and oxantel pamoate did not show any significant activity even at relatively high dose levels.

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Section: Introductionmentioning

confidence: 99%

Efficacy of various anthelmintics against third-stage larvae of Ancylostoma caninum in the brain of mice

Bhopale

Bhatnagar

1988

J. Helminthol.

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“…During such infections, larvae remain in the skin (Beaver, 1956;1964), some migrate to the lungs (Wright and Gold, 1946;Kalmon, 1954) and also appear in the sputum (Muhleisen, 1953). However, Baldone et al (1964) and Nadbath and Lawlor (1965) reported an unknown species of hookworm larvae in the human cornea.…”

mentioning

confidence: 99%

The distribution of Ancylostoma caninum larvae in the central nervous system of the mouse infected with single or repeated doses

Bhopale

Johri

1978

J. Helminthol.

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The distribution of Ancylostoma caninum larvae in the various regions of the central nervous system of mice of previously uninfected or reinfected groups was studied. Although a dose of 4000 larvae was lethal, the distribution of larvae was not appreciable in the CNS. Many larvae were recovered from the cerebral hemispheres and cerebellum of infected mice whereas no incidence of eye involvement was observed in any mouse. In the reinfected mice groups there was a much lower recovery than in the previously uninfected groups in the latent period of study.

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“…In Louisiana, it is the most commonly reported intestinal parasite of dogs of all ages (11). This hookworm of dogs is a known cause of cutaneous larva migrans in humans; it has also been recovered from extradermal sites, including the muscles (12), lungs (13), and cornea (14). It is interesting to note that two of the three previously documented extradermal site isolations were from Louisiana (11,13), as was this case.…”

Section: Discussionmentioning

confidence: 62%

Dog Hookworm

Khoshoo,

Schantz,

Craver

et al. 1994

J. pediatr. gastroenterol. nutr.

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Nematode (Ancylostoma) in the Cornea*

Cited by 13 publications

References 10 publications

Efficacy of various anthelmintics against third-stage larvae of Ancylostoma caninum in the brain of mice

Efficacy of various anthelmintics against third-stage larvae of Ancylostoma caninum in the brain of mice

The distribution of Ancylostoma caninum larvae in the central nervous system of the mouse infected with single or repeated doses

Dog Hookworm

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