Nematicidal metabolites from the fungusPleurotus ferulae Lenzi

Abstract

Pleurotus ferulae Lenzi, a species of edible fungus, was found to have nematicidal activity in experiments searching for nematicidal fungi. Three nematicidal metabolites cheimonophyllon E (compound 1), 5α,8α-epidioxyergosta-6,22-dien-3β-ol (compound 2) and 5-hydroxymethyl-furancarbaldehyde (compound 3) were isolated based on bioassay-guided fractionation from the extracts of the fungus P. ferulae. Their structures were determined by spectroscopic data. All of them showed activities against nematodes Bursaphelenchus xylophilus (Steiner et Buhrer) Nickle and Panagrellus redivivus (Linn.) Goodey. The median lethal concentrations (LC 50 ) of compounds 1, 2 and 3 at 72 h were 70.8, 174.6, and 54.7 mg L -1 respectively against B. xylophilus and were 125.6, 128.1, and 82.8 mg L -1 respectively against P. redivivus. The three compounds were obtained from P. ferulae for the first time.

The efficacy of nematicidal strainSyncephalastrum racemosum

“…Pleurotus ferulae Lenzi, a species of edible fungus, was found to have nematicidal activity in experiments searching for nematicidal fungi. Three nematicidal metabolites were isolated based on bioassay-guided fractionation from the extracts of the fungus P. ferulae (Li et al, 2007). The fungi were isolated from soybean cyst nematode (SCN, Heterodera glycines) eggs collected in China, and 253 fungal isolates were assayed for production of compounds active against SCN and root-knot nematode (RKN, Meloidogyne incognita).…”

Three new cyathane diterpenoids from the medicinal fungusCyathus africanus

“…Medicinal fungi are distributed throughout the world with about 2500 species, and are used in Chinese traditional medicine historically [2]. In particularly, Cyathus is a genus of medical fungi which belongs to the family Nidulariaceae.…”

Metabolites from nematophagous fungi and nematicidal natural products from fungi as alternatives for biological control. Part II: metabolites from nematophagous basidiomycetes and non-nematophagous fungi

“…A yellowish amorphous solid, 5 α ,8 α -epidioxyergosta-6,22-dien-3- β -ol ( 91 ), and a colorless amorphous solid, 5-hydroxymethyl-furancarbaldehyde ( 92 ), were detected in the mycelium acetone extract. The LC 50 values of compounds 90 – 92 against the pine wood nematode ( Bursaphelenchus xylophilus ) were 70.8, 174.6, and 54.7 mg/l, respectively, after 72 h. The LC 50 values against P. redivivus were 125.6, 128.1, and 82.8 mg/l, respectively, after the same exposure (Li et al 2007 ).…”