Neighborhood deprivation and childhood autism: A nationwide study from Sweden

Li, Xinjun; Sjöstedt, Cecilia; Sundquist, Kristina; Zöller, Bengt; Sundquist, Jan

doi:10.1016/j.jpsychires.2014.02.011

Cited by 16 publications

(19 citation statements)

References 42 publications

(54 reference statements)

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“…The data sources were several national Swedish data registers, including the Swedish National Population and Housing Census, the Total Population Register, the Multi-Generation Register, the Swedish Cancer Registry, and the Swedish Hospital Discharge Register and Outpatient Register, and were provided to us by Statistics Sweden (the statistics bureau owned by the Swedish government) and the National Board of Health and Welfare [20–22]. The dataset includes ESRD events for the entire population, as well as information on individual-level SES and neighbourhood-level SES [23–25]. We used the main diagnoses of ESRD recorded in the Hospital Discharge Register and Outpatient Register and surgical codes for renal transplantation and dialysis.…”

Section: Methodsmentioning

confidence: 99%

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End stage renal disease risk and neighbourhood deprivation: A nationwide cohort study in Sweden

Akrawi¹,

Li²,

Sundquist³

et al. 2014

European Journal of Internal Medicine

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Background Chronic kidney disease has been associated with socioeconomic disparities and neighbourhood deprivation. We aimed to determine whether there is an association between neighbourhood deprivation and end stage renal disease (ESRD), and whether this association is independent of individual-level sociodemographic factors and comorbidities. Methods National Swedish data registers were used. The entire Swedish population aged 20–69 years was followed from January 1, 2001 until December 31, 2010. Data were analysed by multilevel logistic regression, with individual-level sociodemographic factors (age, marital status, family income, education level, country of birth, urban/rural status, and mobility) and comorbidities at the first level and neighbourhood deprivation at the second level. Results Neighbourhood deprivation was significantly associated with ESRD (age-adjusted odds ratio [OR] 1.45, 95% confidence interval [CI] 1.34–1.56 in men and OR 1.59, 95% CI 1.44–1.75 in women). The ORs for ESRD in men and women living in the most deprived neighbourhoods remained significantly increased when adjusted for age and individual-level sociodemographic factors (OR 1.25, 95% CI 1.15–1.35 in men and OR 1.30, 95% CI 1.17–1.44 in women). In the full model, which took account of sociodemographic factors and comorbidities, the ORs for ESRD remained significantly increased (OR 1.17, 95% CI 1.07–1.27 in men and OR 1.18, 95% CI 1.06–1.31 in women). Conclusion Neighbourhood deprivation is independently associated with ESRD in both men and women irrespective of individual-level sociodemographic factors and comorbidities.

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Section: Methodsmentioning

confidence: 99%

“…The individual-level variables were sex, age at the start of the study, marital status, family income, education level, country of birth, urban/ rural status, mobility, and comorbidities [23–25]. …”

Section: Methodsmentioning

confidence: 99%

End stage renal disease risk and neighbourhood deprivation: A nationwide cohort study in Sweden

Akrawi¹,

Li²,

Sundquist³

et al. 2014

European Journal of Internal Medicine

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“…Urbanicity has been relatively robustly linked to the development of SSD (Marcelis, Navarro-Mateu, Murray, Selten, & van Os, 1998;Mortensen et al, 1999). Although an association between urbanicity during pregnancy and infanthood and the development of ASD has been observed (Lauritsen et al, 2014;Lauritsen, Pedersen, & Mortensen, 2005;Li, Sjöstedt, Sundquist, Zöller, & Sundquist, 2014), at least some of this observation may be explained by variations in access to diagnostic and medical services.…”

Section: Environmental Factorsmentioning

confidence: 99%

The association between autism and schizophrenia spectrum disorders: A review of eight alternate models of co-occurrence

Chisholm

Lin

Abu‐Akel

et al. 2015

Neuroscience & Biobehavioral Reviews

250

241

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Although now believed to be two distinct disorders, autism spectrum disorders (ASD) and schizophrenia spectrum disorders (SSD) share multiple phenotypic similarities and risk factors, and have been reported to co-occur at elevated rates. In this narrative review, we give a brief overview of the phenomenological, genetic, environmental, and imaging evidence for the overlap between ASD and SSD, highlighting similarities and areas of distinction. We examine eight possible alternate models of explanation for the association and comorbidity between the disorders, and set out a research agenda to test these models. Understanding how and why these disorders co-occur has important implications for diagnosis, treatment, and prognosis, as well as for developing fundamental aetiological models of the disorders.

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“…The individual-level variables used in models were sex, age at the start of the study, marital status, family income, education level, country of origin, urban/rural status, and chronic conditions related to MI (comorbidities) [ 14 – 16 ].…”

Section: Methodsmentioning

confidence: 99%

Neighborhood socioeconomic characteristics and statin medication in patients with myocardial infarction: a Swedish nationwide follow-up study

Forsberg

Sundquist

2016

BMC Cardiovasc Disord

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BackgroundCoronary heart disease (CHD) and myocardial infarction (MI) are associated with neighborhood-level socioeconomic status (SES). Statins are important drugs for secondary prevention of MI. However, no study has determined whether neighborhood-level SES is associated with statin medication in MI patients. We aimed to determine whether there is a difference in statin medication rate in MI patients across different levels of neighborhood SES.MethodsAll patients in Sweden, diagnosed with incident MI from January 1st, 2000 until December 31st 2010, were followed (n = 116,840). Of these, 89.7 % received statin medication. Data were analyzed by multilevel logistic regression, with individual-level characteristics (age, marital status, family income, educational attainment, country of origin, urban/rural status and comorbidities/chronic conditions related to MI) as covariates.ResultsLow neighborhood-level SES was significantly associated with low statin medication rate (Odds Ratio 0.80). In the full model, which took into account individual-level socioeconomic characteristics and MI comorbidities, the odds no longer remained significant.ConclusionsIndividual-level approaches may be most important in health care policies regarding statin medication in MI patients.Electronic supplementary materialThe online version of this article (doi:10.1186/s12872-016-0319-y) contains supplementary material, which is available to authorized users.

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Neighborhood deprivation and childhood autism: A nationwide study from Sweden

Cited by 16 publications

References 42 publications

End stage renal disease risk and neighbourhood deprivation: A nationwide cohort study in Sweden

End stage renal disease risk and neighbourhood deprivation: A nationwide cohort study in Sweden

The association between autism and schizophrenia spectrum disorders: A review of eight alternate models of co-occurrence

Neighborhood socioeconomic characteristics and statin medication in patients with myocardial infarction: a Swedish nationwide follow-up study

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