Negative Pressure Wound Therapy in Pediatric Burn Patients: A Systematic Review

Pedrazzi, Nadine; Naiken, Surennaidoo P.; Scala, Giorgio La

doi:10.1089/wound.2019.1089

Cited by 10 publications

(13 citation statements)

References 15 publications

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“…В связи с отсутствием клинических реко мендаций показания к применению вакуумной терапии у пострадавших с ожоговой травмой в большей степени зависят не от объективных причин, а от личного опыта и предпочтений врачебного персонала. По данным зарубеж ных авторов, этиологический фактор травмы не играет решающей роли при выборе мето да лечения в пользу вакуума [14]. Наиболее часто закрытие ран с помощью таких повязок применяют у пострадавших от воздействия высоковольтного электричества [8,11,15] и раскаленных предметов [14,15,20].…”

Section: Introductionunclassified

“…По данным зарубеж ных авторов, этиологический фактор травмы не играет решающей роли при выборе мето да лечения в пользу вакуума [14]. Наиболее часто закрытие ран с помощью таких повязок применяют у пострадавших от воздействия высоковольтного электричества [8,11,15] и раскаленных предметов [14,15,20]. Не сколько реже данный метод используют для лечения ожогов пламенем и химических пора жений.…”

Section: Introductionunclassified

“…Большинство специалистов ожоговых центров регулярно сталкиваются с необхо димостью восстановления кожного покрова у пострадавших с обширными дефектами покровных тканей неожоговой этиологии. К таким «непрофильным» пациентам мож но отнести пострадавших с минновзрывной и сочетанной травмой, травматическими отслойками мягких тканей, лучевыми пора жениями и т. д. Применение вакуумной тера пии у такого рода пациентов позволяет су щественно сократить сроки подготовки ран к выполнению кожной пластики и улучшить ее результаты [14,18]. Также описаны единич ные случаи успешного применения метода локального отрицательного давления при ле чении пациентов с токсическим эпидермаль ным некролизом [15].…”

Section: Introductionunclassified

“…Основными показаниями к применению вакуумной терапии, что согласуется с данны ми литературы, оказались стимуляция роста грануляционной ткани и санация гнойных оча гов [10,14,19]. В первом случае метод приме няли у ослабленных пациентов с обширными длительно существующими ранами, которые не удавалось подготовить к кожной пластике другими методами.…”

Section: Introductionunclassified

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Experience of using vacuum therapy in the burn department

Vagner

Zinoviev

Soloshenko

et al. 2021

Med.-biol. soc.-psihol. probl. bezop. črezvyčajnyh situac.

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Relevance. Indications, application techniques and contraindications for the use of vacuum therapy in surgery and orthopedics are formulated in clinical guidelines and are generally available. Indications for the use of a vacuum in patients with severe burns are scattered and depend on personal experience and preferences of the medical staff, and not on objective reasons.Intention. To analyze the results of using Negative Pressure Wound Therapy (NPWT) in patients of burn departments.Methodology. The study included 56 patients treated with local negative pressure in the Department of thermal injuries of the Saint-Petersburg institute of emergency care named after I.I. Dzhanelidze in 2017–2020. Statistical data processing was performed using Microsoft Office Excel 2007 and IBM SPSS 20.0 using descriptive and non-parametric statistics.Results and their Discussion. The frequency of using VAC-therapy in patients with burn injuries was 0.8 % (56 of 6764). The most common reasons for hospitalization of patients were contact injuries – 20 (36 %) and flame burns – 18 (32 %). The main indications for NPWT were stimulation of granulation formation – 21 (38 %), control of wound infection – 20 (36 %), and temporary wound closure after early excisions or atypical amputations – 11 (20 %). The main contraindications to the use of the method were cognitive disorders or impaired consciousness. The primary complication was the depressurization of the dressings, which we encountered in 9 cases (16 %). The expected results of vacuum therapy were achieved in 49 patients (88 %).Conclusion. Local negative pressure is relatively rarely used in burn treatment. A positive effect from the use of NPWT can be expected in the control of wound infections and in the preparation of wounds for skin grafting. The prospects for the introduction of the method can be considered its application in the treatment of partial-thickness burns and additional fixation of skin grafts. To objectify the choice of modes and duration of vacuum therapy in burned patients, it is necessary to conduct further multicenter studies with the preparation of clinical guidelines.

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Section: Introductionunclassified

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Experience of using vacuum therapy in the burn department

Vagner

Zinoviev

Soloshenko

et al. 2021

Med.-biol. soc.-psihol. probl. bezop. črezvyčajnyh situac.

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“…1,2 Despite the continuous debate concerning the evidence of its' effects on wound healing, 3 NPWT is an established treatment method for various difficult to treat traumatic and surgical wounds including burns. 4,5 NWPT is thought to function as an "active dressing" acting through various mechanical and biochemical mechanisms like increased blood flow, mechanical strain, reduction in bioburden and removal of edema, toxins, and matrix metalloproteinases. 1,6 NPWT is thought to stabilize the wound environment and to stimulate granulation tissue and angiogenesis.…”

Section: Introductionmentioning

confidence: 99%

Negative pressure wound treatment in a neonate with epidermolysis bullosa simplex severe generalized: A case report

Schlueer

Schwieger‐Briel

Theiler

et al. 2020

Pediatric Dermatology

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Negative pressure wound treatment (NPWT) is very useful for the treatment of chronic or deep wounds and in the setting of skin grafting. Due to the need for adhesive dressings, this treatment is rarely attempted in patients with skin fragility secondary to hereditary epidermolysis bullosa (EB). We present a neonate with EB simplex, severe generalized in a critical clinical state where NPWT was successfully applied and describe the measures taken to avoid any further skin damage. This case is of clinical importance to physicians and health care staff treating patients with this rare disease where additional therapeutic measures for the treatment of chronic wounds are scarce.

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Bioadhesives with Antimicrobial Properties

et al. 2023

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Bioadhesives with antimicrobial properties enable easier and safer treatment of wounds as compared to the traditional methods such as suturing and stapling on a variety of medical conditions. Composed of natural or synthetic polymers, these bioadhesives seal wounds and facilitate healing while preventing infections through the activity of locally released antimicrobial drugs, nanocomponents or inherently antimicrobial polymers. Although many different materials and strategies are employed to develop antimicrobial bioadhesives, the design of these biomaterials necessitates a prudent approach as achieving all the required properties including optimal adhesive and cohesive properties, biocompatibility, and antimicrobial activity can be challenging. Designing antimicrobial bioadhesives with tunable physical, chemical and biological properties will shed light on the path for future advancement of bioadhesives with antimicrobial properties. In this review, we discuss the requirements and commonly used strategies for developing bioadhesives with antimicrobial properties. In particular, we will summarize different methods for their synthesis and will review their experimental and clinical applications on a variety of organs. Advances in the design of bioadhesives with antimicrobial properties will pave the way for a better management of wounds to increase positive medical outcomes.This article is protected by copyright. All rights reserved

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Negative Pressure Wound Therapy in Pediatric Burn Patients: A Systematic Review

Cited by 10 publications

References 15 publications

Experience of using vacuum therapy in the burn department

Experience of using vacuum therapy in the burn department

Negative pressure wound treatment in a neonate with epidermolysis bullosa simplex severe generalized: A case report

Bioadhesives with Antimicrobial Properties

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