Negative pressure wound therapy in patients with diabetic foot

Ulusal, Ali̇ Engi̇n; Şahin, Mehmet Şükrü; Ulusal, Betül Gözel; Çakmak, Gökhan; Tuncay, Cengiz

doi:10.3944/aott.2011.2283

Cited by 27 publications

(16 citation statements)

References 16 publications

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“…NPT is a non-invasive method with partially understood mechanisms of action [30], which is based on the exertion on the wound of a sub-atmospheric negative pressure within the range of -50 mmHg and -175 mmHg, via polyurethane or polyvinyl alcohol sponge, fixed to the wound by an adhesive foil that provides a waterproof environment. The pressure and suction effect are provided by a digitally controlled pump, connected to the sponge by a flexible tube, and the exudates are collected in a receivertank with a capacity of 500 mL or 1000 mL [31]. NPT acts on interstitial fluid excess, thus reducing edema, improving tissue perfusion and removing infectious factors.…”

Section: Resultsmentioning

confidence: 99%

Advantages of Negative Pressure Therapy in Local Diabetic Foot Treatment

Tantu¹,

Man²,

Păunescu³

et al. 2019

Rev. Chim.

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Diabetic foot is a current public health problem and a late consequence of diabetes. Morbidity and mortality are significant, seriously affecting the patient�s quality of life. Treatment of the diabetic foot is a long-lasting, highly resource-consumption process. Using negative pressure therapy leads to shorter hospitalization periods, better functional outcomes, significantly contributes to decreasing the number of amputations and improving patient�s quality of life. 49 year-old patient is hospitalized with necrotizing at right foot and shank, neglected type II diabetes. It is performed amputation of atypical necessity, right leg, transtarsal, open stump. After successive debridements, negative pressure therapy is installed for a period of 24 days. This favors the formation of the granular bed, the remission of the infection, allowing grafting. The graft is partially integrated and plantar reconstruction is performed with sural reversal flap. The local and functional results are satisfactory, with the flap viability and the possibility of moving with support on the right leg, preventing the amputation of the shank. Negative pressure therapy has a multitude of advantages, it is preferable to conventional therapies, and it can have higher costs, but accelerates healing and improves the quality of life of the patient.

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Section: Resultsmentioning

confidence: 99%

Advantages of Negative Pressure Therapy in Local Diabetic Foot Treatment

Tantu¹,

Man²,

Păunescu³

et al. 2019

Rev. Chim.

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“…The mean age of the patients was 58.2 years in VAC group and 57.2 years in conventional dressing group. In a similar study evaluating the effect of negative pressure wound therapy in patients with diabetic foot, there were 15 patients treated with VAC; ten men and five women, [17]. In another study, measuring the influence of the application of platelet-enriched plasma in oral mucosal wound healing ten patients were included in the study, five males and five females, with a mean age of 54.2+/−9.1 years for females and 57.6+/−6.9 years for males [18].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the use of vacuum-assisted closure (VAC) and platelet-rich plasma gel (PRP) in management of complex wounds

et al. 2015

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“…Nather et al reported a 100% limb salvage in 11 patients with diabetic foot ulcers treated with VAC therapy, presenting Wagner grade 2 or 3 wounds with an average length of stay of 23·3 days. Ulusal et al reported an amputation rate of 37% , with an average hospitalisation of 32 days. The reason for this higher amputation rates in comparison to those in the literature is that 80% of the subjects had Wagner Grade 3 and 4 wounds.…”

Section: Discussionmentioning

confidence: 99%

VAC therapy to promote wound healing after surgical revascularisation for critical lower limb ischaemia

Caridi

Massara

Greco

et al. 2014

International Wound Journal

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Vacuum-assisted closure (VAC) therapy is a new emerging non-invasive system in wound care, which speeds up wound healing by causing vacuum, improving tissue perfusion and suctioning the exudates, and facilitating the removal of bacteria from the wound. The application of sub-atmospheric pressure on the lesions seems to alter the cytoskeleton of the cells on the wound bed, triggering a cascade of intracellular signals that increase the rate of cell division and subsequent formation of granulation tissue. The aim of this study is to analyse the results of VAC therapy used as an adjuvant therapy for the treatment of foot wounds in patients affected by critical limb ischaemia (CLI) (Rutherford 6 class) after distal surgical revascularisation, to promote and accelerate the healing of ulcers. Twenty-nine patients (20 males, 9 females; mean age 68·4) affected by CLI of Rutherford 6 class, after surgical revascularisation of the lower limb, underwent VAC therapy in order to speed up wound healing. Complete wound healing was achieved in 19 patients (65·51%), in an average period of 45·4 ± 25·6 days. VAC therapy is a valid aid, after surgical revascularisation, to achieve rapid healing of foot lesions in patients with CLI.

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Negative pressure wound therapy in patients with diabetic foot

Abstract: VAC therapy, together with debridement and appropriate antibiotic therapy, enables a higher rate of limb salvage, especially in Wagner Grade 3 and Grade 4 ulcers.

Cited by 27 publications

References 16 publications

Advantages of Negative Pressure Therapy in Local Diabetic Foot Treatment

Advantages of Negative Pressure Therapy in Local Diabetic Foot Treatment

Evaluation of the use of vacuum-assisted closure (VAC) and platelet-rich plasma gel (PRP) in management of complex wounds

VAC therapy to promote wound healing after surgical revascularisation for critical lower limb ischaemia

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