Negative Impact of Episodic Migraine on a University Population: Quality of Life, Functional Impairment, and Comorbid Psychiatric Symptoms

Objectives This study aims to examine the association between migraine, major depressive disorder (MDD), and generalized anxiety disorder (GAD) in adolescents and young adults. Background MDD, GAD, and migraine are often comorbid, with adult migraineurs having twice the rate of MDD as nonmigraineurs and more disabling migraines. Findings in children are less consistent; but anxiety disorders, including GAD, are prevalent among youth. Data on the association between MDD, GAD and migraine in adolescents and young adults are sparse. Methods Participants (N=227), between 15 and 20 years old, who were unmedicated or within one month of beginning antidepressant treatment underwent a comprehensive assessment to establish the presence of MDD and GAD, according to the Diagnostic & Statistical Manual, Fourth Edition, Text Revision, and to rate their symptom severity using the Longitudinal Interval Follow-up Evaluation for Adolescents. They then completed the ID Migraine. The Student’s t test and chi-square test were used to compare continuous and categorical variables, respectively, across participants with vs. without migraine. Logistic regression analysis examined the association between the presence of migraine and psychopathology. Results A diagnosis of MDD was associated with significantly increased risk of having migraine. Moreover, more severe and persistent ratings of depression were associated with an even higher likelihood of having migraine. A diagnosis of GAD was also significantly associated with the presence of migraine. The prevalence of comorbid MDD and GAD was significantly higher in participants with migraine than in those without migraine (55% vs. 22%, p<0.0001). When examined concurrently, GAD remained significantly associated with migraine, with a statistical trend for MDD to be associated with it. The use of selective serotonin reuptake inhibitors did not significantly alter these findings and serum vitamin D concentration was not associated with any of the disorders. Conclusions The comorbidity of migraine, MDD, and GAD has important clinical and research implications. Shared psychological and biological vulnerabilities may be involved in the three conditions. Greater understanding of the shared vulnerabilities can lead to unified treatments. ClinicalTrials.gov Identifier NCT02147184

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“…4 The prevalence of migraine differs by age and sex. 5 Among females, it increases from 7.0% before the age of 14 years to 9.7% by age 20.…”

Section: Introductionmentioning

confidence: 99%

Comorbidity of Migraine, Major Depressive Disorder, and Generalized Anxiety Disorder in Adolescents and Young Adults

et al. 2016

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“…Migraine is highly prevalent among university students and it is associated with impaired academic performance and limited daily activities [3]. It has negative effects among university students, who indeed require constant concentration and high level of performance [4].…”

Section: Introductionmentioning

confidence: 99%

Migraine among medical students in Kuwait University

et al. 2014

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BackgroundMedical students routinely have triggers, notably stress and irregular sleep, which are typically associated with migraine. We hypothesized that they may be at higher risk to manifest migraine. We aimed to determine the prevalence of migraine among medical students in Kuwait University.MethodsThis is cross-sectional, questionnaire-based study. Participants who had two or more headaches in the last 3 months were subjected to two preliminary questions and participants with at least one positive response were asked to perform the validated Identification of Migraine (ID Migraine™) test. Frequency of headache per month and its severity were also reported.ResultsMigraine headache was suggested in 27.9% subjects based on ID-Migraine™. Migraine prevalence (35.5% and 44%, versus 31.1%, 25%, 21.1%, 14.8%, 26.5%, p < 0.000), frequency (5.55 + 1.34 and 7.23 + 1.27, versus 3.77 ± 0.99, 2.88 ± 0.85, 3.07 ± 0.96, 2.75 ± 0.75, 4.06 ± 1.66, p < 0.000); and severity of headache (59.1% and 68.2%, versus 28.3%,8.3%, 6.7%,16.7%, p < 0.000; were significantly increased among students in the last 2 years compared to first five years of their study. Stress 43 (24.9%), irregular sleep 36 (20.8%), and substantial reading tasks 32 (18.5%), were the most common triggering factors cited by the students.ConclusionThe prevalence of migraine is higher among medical students in Kuwait University compared to other published studies. The migraine prevalence, frequency and headache severity, all increased in the final two years of education.

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“…Migraine is very common among students of universities and it is linked to the limited daily activities and impaired performance on the academic level (5) .…”

Section: Background:-mentioning

confidence: 99%

Prevalence of Migraine Among Female Students at Taibah University, Kingdom of Saudi Arabia.

Garah¹,

Neyaz²,

Shaqrun³

et al. 2016

IJAR

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Background:-University studentsare routinelycomplaining of triggers, especiallyirregular sleepand stress, which are commonly associated with migraineattacks. Objectives:-To assess the prevalenceof migraine headache among female students at Taibah University (Saudi Arabia) and to determine the common triggering and palliative factors of migraine headache among female University students. Methods:-A cross-sectional study was carried out among female university students.Participants who had suffered from two or more headaches in the previous 3 months were subjected to the IDMigraine screening test, then who had at least two positive answers of the screening test were confirmed as a migraineursbased on the diagnostic criteria of the International Headache Society for migraine. Results:-Migraine was detected among 244 out of 395 students (61.8%).Physical stimulation as (light, loudness, change in weather, certain smells) were the most triggering factors of migraine in 170/244 (69.7%) of migraine students. The most important relieving factors were rest and sleep in 155/244 (63.5%), medication in (33.2%), followed by darkening room in (30.3%), message in (20.1%), and coffee drink in (18%) of migraine students. This study showed significant association between migraine headache and family history of migraine and studying in theoretical colleges. Conclusions:-The prevalenceof migraine among female students in Taibah University was high in comparison to other studies. The study recommend raising awareness towards migraine among students and teaching them how to deal with such a disabling condition to achieve optimum coping techniques aiming to a better quality of life.Copy Right, IJAR, 2013,. All rights reserved.

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Negative Impact of Episodic Migraine on a University Population: Quality of Life, Functional Impairment, and Comorbid Psychiatric Symptoms

Abstract: Episodic migraine is associated with negative impact in numerous domains among university students. These findings replicate and extend those of studies on other samples and have implications for future research studies with this population.

Cited by 78 publications

References 43 publications

Comorbidity of Migraine, Major Depressive Disorder, and Generalized Anxiety Disorder in Adolescents and Young Adults

Comorbidity of Migraine, Major Depressive Disorder, and Generalized Anxiety Disorder in Adolescents and Young Adults

Migraine among medical students in Kuwait University

Prevalence of Migraine Among Female Students at Taibah University, Kingdom of Saudi Arabia.

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