Negative attitudes toward aging mediated the association between HIV status and depression among older people in mainland china

Luo, Sitong; Yang, Xue; Wang, Zixin; Qin, Pei; Jiang, Hongwei; Chen, Xi; He, Jianmei; Huang, Bishan; Lau, Joseph T. F.

doi:10.1016/j.jad.2020.09.031

Cited by 8 publications

(5 citation statements)

References 52 publications

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“…The SF-12 QoL scores observed in our study were lower than scores in the general populations in other middleincome countries, for both physical and mental health [41]. This is consistent with evidence of the high burden of mental health disorders among PLHIV globally, including that HIVpositive individuals are twice as likely to be diagnosed with depression as HIV-negative individuals [42][43][44]. Approximately one in five patients in our study reported depressive symptoms, lower than the rate of 47% among PLHIV in a pooled meta-analysis from middle-income countries [40].…”

Section: Adherencesupporting

confidence: 88%

Patient-Reported Treatment Satisfaction and Quality of Life Among People Living with HIV Following the Introduction of Dolutegravir-Based ART Regimens in Ukraine

et al. 2021

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In 2017, the government of Ukraine initiated its ART Optimization Initiative, revising its national antiretroviral therapy (ART) guidelines and embracing Dolutegravir (DTG) as a backbone of first-line ART regimens. A cross-sectional survey of 464 ART patients from 22 large ART clinics was carried out in mid-2019. The survey assessed patient-reported outcomes (PROS) including treatment satisfaction, physical health, mental health, depression, side effects of ART, and adherence. The associations between ART regimen and PROs were assessed using bivariable and multivariable generalized estimating equations (GEE) models. More than half (55.6%) of the patients were satisfied with their current ART regimen. Less than a half (45.3%) considered their physical health as good while only 36.9% rated their mental health as good, 21.3% reported moderate or severe depression, 82.3% reported no side effect in the past 4 weeks, and 44.4% reported not missing ART medication in the past month. In adjusted analysis, patients starting ART with DTG had higher treatment satisfaction compared to people continuing LPV-based regimens (aOR = 0.49, 95% confidence interval: 0.22-0.90). Also in adjusted analyses, unemployment, low income, and history of injection drug use were associated with unfavorable PROs. While the results indicate modestly favorable effects of ART Optimization, there is clearly a need for complementary interventions to improve PROs among disadvantaged ART patients in Ukraine.

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Section: Adherencesupporting

confidence: 88%

Patient-Reported Treatment Satisfaction and Quality of Life Among People Living with HIV Following the Introduction of Dolutegravir-Based ART Regimens in Ukraine

et al. 2021

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“…Holding negative attitudes toward aging, on the other hand, may lead to negative emotional and psychological states, which in turn may affect life's thriving and overall quality of life. Existing evidence shows that attitude toward own aging is associated with several detrimental psychological and physical outcomes among older adults [21]. Specifically, older adults with a more negative attitude toward own aging tend to encounter higher risks of negative psychological outcomes [22].…”

Section: Is Thriving In Life Related To Quality Of Life and Suicidal ...mentioning

confidence: 99%

“…One study demonstrated that a positive attitude toward own aging helps elderly people reduce negative psychological symptoms, promote healthy behavior, and that older adults with such a positive attitude had higher QoL [43]. Moreover, in older adults, attitude toward own aging has been linked to several detrimental psychological/physical outcomes [44], including anxiety, depression [21], and more cardiovascular stress and mental illness [45]. Our evidence also depicts the moderating effect of attitude toward own aging on the association between thriving in life and QoL, where this association was stronger among older people with a more negative attitude toward own aging than among their counterparts.…”

Section: A Negative Attitude Toward Own Aging Strengthens the Impact ...mentioning

confidence: 99%

The association among thriving in life, quality of life, and suicidal ideation in Chinese urban older adults: the moderating effects of attitude toward own aging

Zhang,

Liu,

Wang

et al. 2024

BMC Psychol

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Background As the global trend of population aging intensifies, the health and well-being of the older population has gradually become a focus of attention for the global community. This study assessed the status of thriving in life among Chinese urban older adults and identified its relationship with attitude toward own aging and quality of life (QoL). It also tested whether attitude toward own aging moderates the association between thriving in life and Qol or between thriving in life and suicidal ideation. Methods Primary data were collected through a cross-sectional survey among urban older adults from three provinces in China. They were invited to complete an anonymous survey using face-to-face interviews from December 2019 to January 2020. Data from 764 older adults were analyzed. Results Approximately 44.39% of participants reported positive responses toward the four domains of thriving in life. Thriving in life and attitude toward own aging had a significant association with QoL. Thriving in life was a protective factor for suicidal ideation for older adults. Moreover, attitude toward own aging moderated the association between thriving in life and QoL and that between thriving in life and suicidal ideation. Conclusions Chinese urban older adults were reportedly thriving in life, which contributed to increased QoL and reduced suicidal ideation. Notably, the study revealed that more positive attitudes towards own aging were associated with higher levels of thriving in life, better QoL, and reduced suicidal ideation. Targeted interventions for older adults should be devised to promote thriving in life and prevent negative attitudes of older people towards their own aging, further raising QoL and reducing suicidal ideation.

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“…The psychosocial literature in this review may be more representative of OPLWH than the literature describing physical issues associated with aging with HIV because the population has diverse identifying characteristics, and experience mental health, social interaction, personal control, and QoL issues that may not be present in people aging without HIV and younger PLWH [7,23,24]. Due to chronic stress associated with both aging and living with HIV, OPLWH may be at increased risk of adverse mental health outcomes than younger PLWH [25].…”

Section: Psychosocial Challengesmentioning

confidence: 99%

From surviving to thriving: the current status of the behavioral, social, and psychological issues of aging with HIV

Ruiz

Greene

Galea

et al. 2022

Current Opinion in HIV and AIDS

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Purpose of reviewDespite significant advances in knowledge regarding the biological and clinical issues related to aging with HIV, significantly less research has centered on related psychological, behavioral, and social issues, which are increasingly recognized as important for successfully aging with HIV. Recent findingsBarriers to successful aging include physical challenges from a sociobehavioral perspective, psychosocial challenges, and system-level challenges. In contrast, several resiliencies and interventions that help facilitate healthy aging with HIV are also emerging. Comprehensive interventions to address the physical, mental, and psychosocial needs of older people living with HIV (OPLWH) are necessary. ConclusionTo promote healthy aging with HIV, we must utilize both clinical and biopsychosocial interventions. The lack of data on the needs of OPLWH is an important barrier to healthy aging in this population.

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Negative attitudes toward aging mediated the association between HIV status and depression among older people in mainland china

Cited by 8 publications

References 52 publications

Patient-Reported Treatment Satisfaction and Quality of Life Among People Living with HIV Following the Introduction of Dolutegravir-Based ART Regimens in Ukraine

Patient-Reported Treatment Satisfaction and Quality of Life Among People Living with HIV Following the Introduction of Dolutegravir-Based ART Regimens in Ukraine

The association among thriving in life, quality of life, and suicidal ideation in Chinese urban older adults: the moderating effects of attitude toward own aging

From surviving to thriving: the current status of the behavioral, social, and psychological issues of aging with HIV

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