Neem flower extract assisted green synthesis of copper nanoparticles – Optimisation, characterisation and anti-bacterial study

Gopalakrishnan, V. K.; Muniraj, Sarangapani

doi:10.1016/j.matpr.2020.07.013

Cited by 31 publications

(6 citation statements)

References 17 publications

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“…Especially, various parts of neem plants have been used for dermatological applications like bacterial and fungal infections. The Neem plant has enormous medicinal properties like anti-bacterial (10,11), anti-fungal (12,13), anti-inflammatory (14,15), antioxidant (16,17), chemopreventive, antifertility (18,19), and anti-cancer activities (20,21,22). It has several potential secondary metabolites such as nimbin, nimbidin, nimbolide, nimbin, azadirachtin, neeflone, flowerine, flowerone, o-methylazadironolide, diepoxyazadirol, etc., (23).…”

Section: Introductionmentioning

confidence: 99%

Correlation Between Antioxidant Property and Total Phenolic and Flavonoid Content of Azadirachta indica A Juss Flowers

Mohanasundaram

Saral

2022

ECS Trans.

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The present study investigated the antioxidant activity of shade dried neem flower powder extracts by DPPH, phospomolybdenum, and FRAP methods respectively. The antioxidant activity of different extracts of neem flower powder has been investigated. Among them, 80% hydroalcoholic extract displayed the highest scavenging activity with the IC50 value of 18 mg/L in phospomolybdenum assay, 29 mg/L in DPPH, 30 mg/L in FRAP assay. Whereas Pet. ether (PE) extract shows lowest antioxidant potential amongst them with the IC50 value of 76 mg/L in FRAP, 37 mg/L DPPH, 28 mg/L in phospomolybdenum assay. On examining the total phenolic and flavonoid content of extracts, 80% hydroalcoholic extract possesses the greatest phenolic content about 83.88 mg/L followed by methanol, acetone and PE about 62.05, 7.52, 3.56 mg/L respectively. The highest flavonoid content of 57.36 mg/L in 80% hydroalcoholic extract followed by methanol, acetone and PE about 20.56, 11.25, 1.56 mg/L respectively. The order of total phenolic and flavonoid content of extracts are found to be: 80% hydroalcoholic > methanol > acetone > pet. ether respectively. The correlation between the antioxidant and total phenolic and flavonoid content was calculated using Prism Pad software and observed at 95% confidence interval level. From the correlation graph, it is observed that there is a good correlation between antioxidant, total phenolic (phospomolybdenum assay, R2 – 0.702), and total flavonoid (DPPH assay, R2 – 0.665) content, and it is possible to suggest that total phenolic and flavonoid content of the plant extracts are the reason for the antioxidant activity.

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Section: Introductionmentioning

confidence: 99%

Correlation Between Antioxidant Property and Total Phenolic and Flavonoid Content of Azadirachta indica A Juss Flowers

Mohanasundaram

Saral

2022

ECS Trans.

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“…These parameters were selected based on optimization reports from previous studies on the synthesis of SeNPs with plant extracts. The incubation pressure and the volume of the extract also influence the synthesis of SeNPs but were not considered in this study [ 41 , 42 ].…”

Section: Discussionmentioning

confidence: 99%

Phytofabrication of Selenium Nanoparticles with Moringa oleifera (MO-SeNPs) and Exploring Its Antioxidant and Antidiabetic Potential

Ahamad Tarmizi,

Nik Ramli,

Adam

et al. 2023

Molecules

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The advancement in nanotechnology is the trigger for exploring the synthesis of selenium nanoparticles and their use in biomedicine. Therefore, this study aims to synthesize selenium nanoparticles using M. oleifera as a reducing agent and evaluate their antioxidant and antidiabetic potential. Our result demonstrated a change in the color of the mixture from yellow to red, and UV-Vis spectrometry of the suspension solution confirmed the formation of MO-SeNPs with a single absorbance peak in the range of 240–560 nm wavelength. FTIR analysis revealed several bioactive compounds, such as phenols and amines, that could possibly be responsible for the reduction and stabilization of the MO-SeNPs. FESEM + EDX analysis revealed that the amorphous MO-SeNPs are of high purity, have a spherical shape, and have a size of 20–250 nm in diameter, as determined by HRTEM. MO-SeNPs also exhibit the highest DPPH scavenging activity of 84% at 1000 μg/mL with an IC50 of 454.1 μg/mL and noteworthy reducing ability by reducing power assay. Furthermore, MO-SeNPs showed promising antidiabetic properties with dose-dependent inhibition of α-amylase (26.7% to 44.53%) and α-glucosidase enzyme (4.73% to 19.26%). Hence, these results demonstrated that M. oleifera plant extract possesses the potential to reduce selenium ions to SeNPs under optimized conditions with notable antioxidant and antidiabetic activities.

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“…7,8 Apart from silver nanoparticles, neem has also been utilized in synthesizing other nanoparticles, including gold, 9 zinc oxide, 10 titanium dioxide, 11 zero-valent iron, 12 magnesium oxide, 13 iron oxide, 14 silicon oxide, 15 and copper. 16 The unique composition of neem extracts allows successful reduction and stabilization of these nanoparticles, making neem an attractive and eco-friendly alternative to conventional chemicals. The synthesis of nanoparticles using neem offers several advantages.…”

Section: Introductionmentioning

confidence: 99%

One-pot synthesis of carbon dots from neem resin and the selective detection of Fe(ii) ions and photocatalytic degradation of toxic dyes

Gokul Eswaran,

Stalin,

Thiruppathi

et al. 2024

RSC Sustain.

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Neem flower extract assisted green synthesis of copper nanoparticles – Optimisation, characterisation and anti-bacterial study

Cited by 31 publications

References 17 publications

Correlation Between Antioxidant Property and Total Phenolic and Flavonoid Content of Azadirachta indica A Juss Flowers

Correlation Between Antioxidant Property and Total Phenolic and Flavonoid Content of Azadirachta indica A Juss Flowers

Phytofabrication of Selenium Nanoparticles with Moringa oleifera (MO-SeNPs) and Exploring Its Antioxidant and Antidiabetic Potential

One-pot synthesis of carbon dots from neem resin and the selective detection of Fe(ii) ions and photocatalytic degradation of toxic dyes

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