Needle tract seeding after vacuum-assisted breast biopsy

Abstract

No displacement of malignant cells within the 11G needle tract was documented. Benign cell displacement was associated with longer VABB duration. The phenomenon of tumor cell dissemination along the needle tract is of questionable clinical significance when the treatment guidelines are followed.

The use of positive core wash cytology to estimate potential risk of needle tract seeding of breast cancer: directional vacuum-assisted biopsy versus automated core needle biopsy

“…This study also showed that the incidence of positive cases for the risk of needle tract seeding of breast cancer for the directional vacuum-assisted biopsy was 33% and the incidence of the risk of displacement, including benign and malignant epithelium, was 34%. The frequency rates were higher than the frequency rates of previous studies based on clinical and histological examinations [3][4][5][13][14][15]. The histological examinations of needle tract seeding in those previous studies might have failed to detect a single tumor cell or a small group of malignant cells because the needle tract seeding rates will increase with intensive histological examination such as multiple sectioning.…”

“…Some investigators have reported the frequency to be 2-38% [3,[13][14][15]. However, the frequency of epithelial displacement and needle tract seeding may be lower with the directional vacuum-assisted device in comparison to the automated core needle gun [4,5]. Liberman et al reported that the displacement of benign epithelium into the parenchyma in 2 (7%) of 28 DCIS lesions with the use of an 11-gauge directional vacuum-assisted device, and no displacement of malignant epithelium [4].…”

“…Liberman et al reported that the displacement of benign epithelium into the parenchyma in 2 (7%) of 28 DCIS lesions with the use of an 11-gauge directional vacuum-assisted device, and no displacement of malignant epithelium [4]. Michalopoulos et al reported the displacement of benign epithelium into the parenchyma in 2 (6.5%) of 10 IDC lesions and 21 DCIS lesions with the 11-gauge directional vacuum-assisted device, and no displacement of malignant epithelium [5]. These frequencies of epithelial displacement were significantly lower in that study than the 28% (12/43) frequency of epithelial displacement after the use of the 14-gauge automated core needle gun reported by Youngson et al (P = 0.037 and P = 0.033) [14].…”

“…Moreover, the frequency of epithelial displacement and needle tract seeding may be lower with the directional vacuum-assisted device in comparison to the automated core needle gun [4,5]. A recent study reported the use of the simple technique of washed-biopsy cytology to estimate the risk of needle tract seeding of breast cancer [6].…”

Local Control of Ductal Carcinoma In Situ Based on Tumor and Patient Characteristics: The Surgeon's Perspective

“…The latter strategy can potentially have an adverse impact on cosmesis with either a lumpectomy or a skin-sparing mastectomy. Several investigators have therefore evaluated LR, needle biopsy, and needle tract seeding issues, and most have found no significant evidence of a correlation; however, precise documentation was generally not provided regarding whether the needle biopsy tract and skin insertion sites were completely resected (29)(30)(31)(32)(33)(34). Thurjfell et al (35) identified 3 cases of LR out of 303 lumpectomy patients where the recurrence was thought to be related to prior needle tract seeding.…”