Needle deflection and tissue sampling length in needle biopsy

Li, Annie; Plott, Jeffrey; Chen, Lei; Montgomery, Jeffrey S.; Shih, Albert J.

doi:10.1016/j.jmbbm.2020.103632

Cited by 22 publications

(19 citation statements)

References 38 publications

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“…For synthetic polymers, PVC and silicone have been studied. PVC has high transparency, making it ideal to observe the tissue interaction with surgical tools, such as the deformation of needle during biopsy procedure (Li et al 2020). To prepare the PVC phantom, vinyl chloride solution is heated to 150 • C to promote optimum polymerization (Li et al 2016).…”

Section: Human Tissuementioning

confidence: 99%

Tissue mimicking materials for imaging and therapy phantoms: a review

et al. 2020

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Tissue mimicking materials (TMMs), typically contained within phantoms, have been used for many decades in both imaging and therapeutic applications. This review investigates the specifications that are typically being used in development of the latest TMMs. The imaging modalities that have been investigated focus around CT, mammography, SPECT, PET, MRI and ultrasound. Therapeutic applications discussed within the review include radiotherapy, thermal therapy and surgical applications. A number of modalities were not reviewed including optical spectroscopy, optical imaging and planar x-rays. The emergence of image guided interventions and multimodality imaging have placed an increasing demand on the number of specifications on the latest TMMs. Material specification standards are available in some imaging areas such as ultrasound. It is recommended that this should be replicated for other imaging and therapeutic modalities. Materials used within phantoms have been reviewed for a series of imaging and therapeutic applications with the potential to become a testbed for cross-fertilization of materials across modalities. Deformation, texture, multimodality imaging and perfusion are common themes that are currently under development.

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Section: Human Tissuementioning

confidence: 99%

Tissue mimicking materials for imaging and therapy phantoms: a review

et al. 2020

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“…The needle and cannula were advanced by the actuators to generate the NCD, NCI, and MPI insertion motions. The transparent polyvinyl chloride (PVC) tissue-mimicking phantom materials with the stiffness and needle insertion properties similar to those of prostate and surrounding muscle tissues 33 , 34 are commonly used as the surrogate of soft tissue in needle insertion experimental studies to observe and quantify needle–tissue interaction 21 , 33 , 35 . Particles can be embedded in the phantom to further visualize and quantify the deformation and displacement of tissue-mimicking phantoms at the local and global scales 29 , 36 , 37 .…”

Section: Resultsmentioning

confidence: 99%

“…Figure 5 d also shows the measured needle insertion forces vs. time. The insertion force presented here is the sum of needle tip force (cutting and contact forces), tissue pressure (compression force), and friction force (increasing with insertion length) 21 . For NCD insertion, the U A and insertion force both kept increasing due to the continuous tissue compression by the direct insertion motion (Fig.…”

Section: Resultsmentioning

confidence: 99%

“…1 e. However, the prostate has been deformed and moved significantly and the target location has been moved away from the predicted path just prior to biopsy. The discrepancy between desired and actual target locations (ranging from mm- to cm-scale) leads to needle mistargeting 21 and lesion undersampling 6 – 9 , especially for those small (5–10 mm) while clinically significant cancer tumors 8 . Such sampling errors have the clinical impact such as false-negative mis- or non-diagnostic biopsy 22 , potentially reducing the cancer diagnostic accuracy 8 .…”

Section: Introductionmentioning

confidence: 99%

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Mosquito proboscis-inspired needle insertion to reduce tissue deformation and organ displacement

Putra

Chen

et al. 2020

Sci Rep

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This study investigates mosquito proboscis-inspired (MPI) insertion applied to the clinically used biopsy needle to reduce tissue deformation and organ displacement. Advanced medical imagining has enabled early-stage identification of cancerous lesions that require needle biopsy for minimally invasive tissue sampling and pathological analysis. Accurate cancer diagnosis depends on the accuracy of needle deployment to the targeted cancerous lesion site. However, currently available needle delivery systems deform and move soft tissue and organs, leading to a non-diagnostic biopsy or undersampling of the target. Two features inspired by the mosquito proboscis were adopted for MPI insertion in prostate biopsy: (1) the harpoon-shape notches at the needle tip and (2) reciprocating needle-cannula motions for incremental insertion. the local tissue deformation and global prostate displacement during the MPI vs. traditional direct insertions were quantified by optically tracking the displacement of particle-embedded tissue-mimicking phantoms. Results show that the MPI needle insertion reduced both local tissue deformation and global prostate displacement because of the opposite needle-cannula motions and notches which stabilized and reduced the tissue deformation during insertion. Findings provide proof of concept for MPI insertion in the clinical biopsy procedures as well as insights of needle-tissue interaction for future biopsy technology development. Mosquito proboscis is an ideal needle device which minimizes the deformation and displacement of surrounding tissue during insertion for accurate guidance to targeted vessels. The proboscis has a hollow labrum (about 25 μm wide) and two maxillae (about 15 μm wide) with harpoon-shape notches on the side 1 as shown in Fig. 1a. During insertion, the proboscis advances incrementally with vibratory relative displacements of the labrum and maxillae for reciprocating tissue penetration 2,3. A study proposed the mechanism of proboscis insertion 1 as illustrated in Fig. 1b. In Step 1, the left maxilla moves forward into the tissue while the labrum retracts a shorter distance in the opposite direction. In Step 2, the labrum moves forward while the maxillae retract utilizing their notches to anchor the surrounding tissue. The forward motion of the right maxilla and backward motion of the labrum in Step 3 mirror the motions in Step 1. In Step 4, movements of both maxillae and the labrum in Step 2 are repeated. After moving the left maxilla forward and the labrum backward in Step 5, the relative positions of the maxillae and labrum are the same as in Step 1. At this state, the proboscis has moved forward by a distance marked by the wide arrow in Fig. 1b. By repeating the above steps, the proboscis incrementally advances with vibratory motions. The vibratory reciprocating motions of mosquito proboscis have been found to reduce insertion force and resultant tissue deformation 3,4. The harpoon-shape notches of the maxillae may further provide critical support and anchoring to reduce tissu...

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“…Notably, these approaches aim to influence the needle deflection as the insertion progresses by means of axial rotation of bevel-tip needles. However, a recurring problem in clinical practice corresponds to performing a straight needle insertion employing multi-bevel needles or needles with axial-symmetric tip [23]. Compared to the insertion of bevel tip needles, this problem has remained relatively unexplored.…”

Section: Introductionmentioning

confidence: 99%