Necrotizing myelopathy associated with multiple myeloma

Abstract

A case of progressive necrotizing myelopathy occurring in the context of multiple myeloma is described, and the pathology illustrated. This association has not been previously reported.

Acute inflammatory myelopathies

“…Furthermore, spinal cord MRI signal changes may improve or resolve with immune suppression (Glantz et al, 1994;Drach et al, 1996;Anderson and Borsaru, 2008;Mueller et al, 2008). Nevertheless, relentless neurologic decline occurs in some patients despite treatment (Storey and McKelvie, 1991;Kuroda et al, 1993;Glantz et al, 1994). Many patients ultimately succumbed to complications from the underlying malignancy (Hughes et al, 1992;Glantz et al, 1994;Urai et al, 2009).…”