Necrotizing myelopathy associated with malignancy caused by herpes simplex virus type 2: Clinical report of two cases and literature review.

Herpes simplex Virus Myelitis: Clinical Manifestations and Diagnosis by the Polymerase Chain Reaction Method

“…In previous reports, HSV myelitis was accompanied by conditions that reduce immunologic competence, such as acquired immunodeficiency syndrome [5,6], malignancies [7,8], and diabetes mellitus [3]. Ellie et al [12] and Flope et al [13] have recently reported HSV myelitis in nonimmunocompromised patients.…”

“…In previous reports, most cases of herpes simplex virus (HSV) myelitis took the form of acute ascending necrotizing myelitis [1][2][3][4][5][6][7][8]. In contrast to HSV encephalitis, most cases of which are due to HSV type 1 (HSV-1), HSV myelitis is due mainly to HSV type 2 (HSV-2).…”

Herpes Simplex Myelitis: Differences in Clinical Manifestations Between Herpes Simplex Virus Type 1 and Type 2

“…Myelitis is rare, and it has been mostly reported as ascending myelitis, necrotizing myelitis or myeloradiculitis (Klastersky et al, 1972;Koskiniemi et al, 1982;Britton et al, 1985;Tucker et al, 1985;Wiley et al, 1987;Ahmed,1988;Nakagawa et al, 1991;. The initial symptoms of herpes simplex myelitis (HSM) are sensory-motor disturbance of lower limbs and urinary disturbance.…”

Herpes Simplex Virus Type 1 Myelitis with a Favorable Outcome.

“…Herpes simplex virus (HSV)myelitis or myelopathy is generally believed to result from genital herpes-HSV type 2, with manyreported cases being fatal ones in immunocompromised hosts (1)(2)(3)(4). Only a few cases ofHSV type 1 (HSV 1) myelitis have been reported to date (1,(5)(6)(7)(8).…”

“…Approximately 20 patients with HSVmyelitis or necrotizing myelopathy have been reported (1)(2)(3)(4)(5)(6)(7)(8). The majority of the cases had HSV2, while only a few had HSV1.…”