Necrotizing Fasciitis in a Neonate

Weinberger, Malvin; Haynes, Ralph E.; Morse, Thomas S.

doi:10.1001/archpedi.1972.02110120115016

Cited by 21 publications

(12 citation statements)

References 7 publications

(2 reference statements)

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“…The predominant organisms causing NF are S. aureus, Pseudomonas aeruginosa, E.coli and anaerobes [60,78,79]. A recent review of the literature [35] of 53 wound cultures of neonatal NF revealed that 39 (74%) were polymicrobial.…”

Section: Bacterial Etiologymentioning

confidence: 99%

“…In the neonate, most cases of NF are attributable to secondary infection, such as omphalitis [6, 37-39, 42, 43, 48, 63, 64, 71], mastitis [6,38], birth trauma balanitis [38,64,71], postoperative complications [24,79], fetal scalp monitoring [66], and bullous impetigo [78], have been reported after circumcision. Other associations of NF included necrotizing enterocolitis [23] immundeficiency [41], and septicemia [51,60].…”

Section: Predisposing Factorsmentioning

confidence: 99%

“…Skin grafting may be required because of poor granulation formation or large postoperative skin defects among the survivors [5,23,31,41,60,66,78]. Death usually occurred before surgery or shortly after surgical intervention as a result of bacterial infection with septic shock, disseminated intravascular coagulation, and/or multiple-organ failure.…”

Section: Prognosismentioning

confidence: 99%

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Cutaneous and subcutaneous infections in newborns due to anaerobic bacteria

Brook¹

2002

Journal of Perinatal Medicine

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This review describes the microbiology and management of the major cutaneous and subcutaneous infections in newborns where anaerobic bacteria predominate: omphalitis, necrotizing fasciitis, breast abscess, and scalp infection following intrauterine fetal monitoring. The predominant bacteria known to cause these infections are group B streptococcus, group D enterococcus, group A streptococcus, Staphylococcus aureus, Enterobacteriaceae, and anaerobic bacteria. All of these agents can colonize or infect the mother and subsequently colonize or infect the fetus or newborn either intrauterinely or during the passage through the birth canal. Infections due to anaerobes are often polymicrobial, and include also aerobic and facultative bacteria. The anaerobes recovered from these infections are Bacteroided fragilis group, Fusobacterium spp., Peptostreptococcus spp. and Clostridium spp. Early recognition and effective medical and surgical therapy are essential to recovery. Managements of these infections include surgical debridement and drainage when appropriate as well as topical and systemic use of antimicrobial agents effective against both aerobic and anaerobic bacteria.

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Section: Bacterial Etiologymentioning

confidence: 99%

Section: Predisposing Factorsmentioning

confidence: 99%

Section: Prognosismentioning

confidence: 99%

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Cutaneous and subcutaneous infections in newborns due to anaerobic bacteria

Brook¹

2002

Journal of Perinatal Medicine

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“…It is often associated with blood stream invasion by the causative pathogen, and the mortality is high. The condition is familiar to the surgeon, but it appears to be rare in children (Wilson and Haltalin, 1973), and only 3 cases have been reported in newborn infants (Weinberger et al, 1972;Ramamurthy et al, 1977). We report a newborn infant who developed septicaemia, meningitis, and necrotising fasciitis caused by group A P-haemolytic streptococcus.…”

mentioning

confidence: 92%

Acute necrotising fasciitis due to streptococcal infection in a newborn infant.

Nutman¹,

Henig²,

Wilunsky³

et al. 1979

Archives of Disease in Childhood

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“…The diagnosis depends on recognition of the characteristic rapidly progressive clinical course and demonstration of ftiU-thickness skin necrosis with involvement of the fascial pities overlying the muscle. The oi^anisms most often recovered are beta-hemolytic Streptococcus or Stapkylococcus aureus, but other aerobic and anaerobic organisms in single or mixed infection have heen reported (1,2,11,12). This infection has a significant mortality rate, necessitating early, aggressive, specific medical and surgical treatment.…”

mentioning

confidence: 99%

Necrotizing Fasciitis in Infancy: Report of Three Cases and Review of the Literature

Goldberg

Hansen

Lynch

1984

Pediatric Dermatology

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Necrotizing fasciitis exists on a continuum of soft tissue infections between cellulitis and myonecrosis. It has been uncommonly reported in infancy (1-10). The diagnosis depends on recognition of the characteristic rapidly progressive clinical course and demonstration of full-thickness skin necrosis with involvement of the fascial planes overlying the muscle. The organisms most often recovered are beta-hemolytic Streptococcus or Staphylococcus aureus, but other aerobic and anaerobic organisms in single or mixed infection have been reported (1, 2, 11, 12). This infection has a significant mortality rate, necessitating early, aggressive, specific medical and surgical treatment.

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Necrotizing Fasciitis in a Neonate

Cited by 21 publications

References 7 publications

Cutaneous and subcutaneous infections in newborns due to anaerobic bacteria

Cutaneous and subcutaneous infections in newborns due to anaerobic bacteria

Acute necrotising fasciitis due to streptococcal infection in a newborn infant.

Necrotizing Fasciitis in Infancy: Report of Three Cases and Review of the Literature

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