Necrotising vasculitis of the skin associated with an herbal medicine containing amfepramone

Halbsguth, Ulrike; Schwanda, Stefanie; Lehmann, Thomas; Ostheeren-Michaelis, Sonja; Fattinger, Karin

doi:10.1007/s00228-009-0632-9

Cited by 5 publications

(1 citation statement)

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“…The recommended amphepramone intake is 75 mg/day [ 245 ], and the adverse effects reported are urticaria, rash, ecchymosis and erythema [ 246 ]. A 52-year-old woman went to the hospital with a rash suggestive of cutaneous vasculitis.…”

Section: Toxicity Of Synthetic Cathinones and Synthetic Cannabinoidsmentioning

confidence: 99%

Novel Psychoactive Substances: The Razor’s Edge between Therapeutical Potential and Psychoactive Recreational Misuse

et al. 2022

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Background: Novel psychoactive substances (NPS) are compounds of natural and synthetic origin, similar to traditional drugs of abuse. NPS are involved in a contemporary trend whose origin lies in a thinner balance between legitimate therapeutic drug research and legislative control. The contemporary NPS trend resulted from the replacement of MDMA by synthetic cathinones in ‘ecstasy’ during the 2000s. The most common NPS are synthetic cannabinoids and synthetic cathinones. Interestingly, during the last 50 years, these two classes of NPS have been the object of scientific research for a set of health conditions. Methods: Searches were conducted in the online database PubMed using boolean equations. Results: Synthetic cannabinoids displayed protective and therapeutic effects for inflammatory, neurodegenerative and oncologic pathologies, activating the immune system and reducing inflammation. Synthetic cathinones act similarly to amphetamine-type stimulants and can be used for depression and chronic fatigue. Conclusions: Despite the scientific advances in this field of research, pharmacological application of NPS is being jeopardized by fatalities associated with their recreational use. This review addresses the scientific achievements of these two classes of NPS and the toxicological data, ending with a reflection on Illicit and NPS control frames.

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Section: Toxicity Of Synthetic Cathinones and Synthetic Cannabinoidsmentioning

confidence: 99%

Novel Psychoactive Substances: The Razor’s Edge between Therapeutical Potential and Psychoactive Recreational Misuse

et al. 2022

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Current awareness: Pharmacoepidemiology and drug safety

2009

Pharmacoepidemiology and Drug

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In order to keep subscribers up‐to‐date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of pharmacoepidemiology and drug safety. Each bibliography is divided into 23 sections: 1 Reviews; 2 General; 3 Anti‐infective Agents; 4 Cardiovascular System Agents; 5 CNS Depressive Agents; 6 Non‐steroidal Anti‐inflammatory Agents; 7 CNS Agents; 8 Anti‐neoplastic Agents; 9 Haematological Agents; 10 Neuroregulator‐Blocking Agents; 11 Dermatological Agents; 12 Immunosuppressive Agents; 13 Autonomic Agents; 14 Respiratory System Agents; 15 Neuromuscular Agents; 16 Reproductive System Agents; 17 Gastrointestinal System Agents; 18 Anti‐inflammatory Agents ‐ Steroidal; 19 Teratogens/fetal exposure; 20 Antidiabetic Agents; 21 Contrast Agents; 22 Bone Conservation Agents; 23 Others. Within each section, articles are listed in alphabetical order with respect to author. If, in the preceding period, no publications are located relevant to any one of these headings, that section will be omitted.

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Noninvasive In Vivo Optical Imaging Models for Safety and Toxicity Testing

Peterson¹

2016

Nutraceuticals

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Necrotising vasculitis of the skin associated with an herbal medicine containing amfepramone

Cited by 5 publications

References 10 publications

Novel Psychoactive Substances: The Razor’s Edge between Therapeutical Potential and Psychoactive Recreational Misuse

Novel Psychoactive Substances: The Razor’s Edge between Therapeutical Potential and Psychoactive Recreational Misuse

Current awareness: Pharmacoepidemiology and drug safety

Noninvasive In Vivo Optical Imaging Models for Safety and Toxicity Testing

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