Necrotising fasciitis

Necrotizing Fasciitis: Case Report and Review of Literature

“…Re-exploration and further debridements are often required to achieve control of the necrotizing process. Repetitive interventions are the rule and survival has been documented after excision of as much as 45% of a patient's surface area (25). Surgical wounds must be frequently reevaluated for evidence of disease extension.…”

Group A streptococcus necrotising fasciitis from a levonorgestrel-containing intrauterine system (‘Mirena’ coil)

“…Clinical presentation is varied and depends largely on the stage of the disease. Necrotising fasciitis is particularly painful in the early stages: severe pain disproportionate to the physical findings, particularly in association with systemic toxicity, should raise the suspicion of necrotising fasciitis (Burge and Watson 1994;Green et al 1996). Later in the progression of the disease, pain may decrease as nerve damage occurs.…”

“…Incidence in the UK is thought to be around 500 new cases a year, although this is difficult to estimate, partly due to confusion surrounding nomenclature and classification (Hasham et al 2005). The number of laboratory reports of systemic infection with group A streptococci in England and Wales has remained stable over the past 3 years (Burge and Watson 1994).…”

Case Report: Necrotising Fasciitis with Epidural Abscess

“…2,3,8,11 It increases the oxygen saturation at the site of infection by a thousand fold. It is useful in both clostridial and non-clostridial infection.…”

“…3,8,[11][12][13][14] Certainly, some authors did not agree with this 4 since there is no large, controlled clinical trial.…”