Necrolytic migratory erythema with cholangiocarcinoma: Pseudoglucagonoma syndrome

Paraneoplastic subacute cutaneous lupus erythematosus associated with cholangiocarcinoma

“…Cholangiocarcinoma is an uncommon tumour that has only rarely been associated with skin eruptions. Isolated cases have been linked to acanthosis nigricans, Leser–Trélat syndrome, Sweets syndrome, erythema multiforme, necrolytic migratory erythema, yellow nail syndrome, adult‐onset Stills disease, polyarteritis nodosa and Bazex syndrome …”

Pseudoglucagonoma syndrome: Description of an ‘Idiopatic’ case

“…The main published cases of pseudoglucagonoma syndrome are reported in Table 1. [5][6][7][8][9][10][11][12][13] Notably, most of the diseases associated with necrolytic migratory erythema can support one or more of the aforementioned pathogenetic theories: thus, a multifactorial model for the pathogenesis seems very likely. In our case, we were unable to detect any associated disease or nutritional deficiency; thus, the case remained 'idiopathic' pseudoglucagonoma syndrome and did not resolve over time.…”

“…The main published cases of pseudoglucagonoma syndrome are reported in Table 1 5‐13 . Notably, most of the diseases associated with necrolytic migratory erythema can support one or more of the aforementioned pathogenetic theories: thus, a multifactorial model for the pathogenesis seems very likely.…”

Normoglycemic glucagonoma syndrome associated with necrolytic migratory erythema

“…This so-called pseudoglucagonoma has been seen in association with intestinal malabsorption disorders, liver cirrhosis and other diseases. 4 Histopathological features of NME are non-specific and may also be seen in zinc deficiency and pellagra. Vacuolated, pale epidermal cells and necrosis of the superficial epidermis are found.…”

“…3 Recently, targeted phototherapy using the 308nm xenon chloride (XeCl) monochromatic excimer light (MEL) delivered by a laser or a lamp emitting non-coherent monochromatic light has been used. 4 In this prospective, controlled study, we aimed to investigate the efficacy of the 308-nm excimer lamp in treating vitiligo and to assess patient satisfaction with treatment.…”