Necrobiosis Lipoidica of the Glans Penis

Alonso, Marina; Rios, Juan Carlos Saenz; González‐Beato, M.J.; Pinto, Pedro Herranz

doi:10.2340/00015555-0993

Cited by 8 publications

(10 citation statements)

References 9 publications

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“…Liapon and Mashkilleison et al reported a case of necrobiosis lipoidica in a non-diabetic patient that clinically resembled Degos’ papulosis [16]. Alonso et al described a case of ulcerated necrobiosis lipoidica on the glans penis that was initially suspicious for squamous cell carcinoma [17]. The ulcer had red borders, a base that was erythematous, and a center that was necrotic.…”

Section: Discussionmentioning

confidence: 99%

Hyperkeratotic necrobiosis lipoidica

Khan

Ramírez-Fort

Chan

et al. 2013

Dermatol Pract Concept

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Section: Discussionmentioning

confidence: 99%

Hyperkeratotic necrobiosis lipoidica

Khan

Ramírez-Fort

Chan

et al. 2013

Dermatol Pract Concept

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“…The lesions are distributed on the anterior and lateral surfaces of the lower legs. However, there are other sites that can rarely be affected, such as upper extremities [1, 2], trunk [1, 3], face (even periorbitally), scalp [1, 3] and penis [3, 4]. …”

Section: Discussionmentioning

confidence: 99%

Necrobiosis Lipoidica: Early Diagnosis and Treatment with Tacrolimus

Patsatsi¹,

Kyriakou²,

Sotiriadis³

2011

Case Rep Dermatol

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We present a case of necrobiosis lipoidica (NL) with atypical early lesions and good response to topical tacrolimus. NL is a disease with clinical features that are seldom misinterpreted. Often histology just confirms the clinician’s diagnosis. Only in rare cases, the clinical presentation and the involved body sites may be misleading. A 67-year-old diabetic woman was admitted to our department with a well-defined, persistent plaque on her left arm and on her right shin. Histologic examination of both lesions revealed features of NL despite the dissimilar clinical presentation. The patient was treated with 0.1% topical tacrolimus ointment twice daily for 8 weeks and once daily for 8 weeks. A significant improvement and no further lesions were observed after 1 year of follow-up. A high index of suspicion regarding NL lesions with atypical clinical presentation on different body sites is advised in order to avoid misdiagnosis, wrong treatment decisions and ulceration. Additionally, it appears that topical tacrolimus treatment is an effective therapeutic option in patients with recent, non-ulcerated NL lesions.

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“…However, the granulomas in GA are typically more superficial with larger amounts of mucin in their centers. [31][32][33] NL has also been reported in atypical locations, such as the back and nipple. 34 Histopathology shows interstitial and palisading necrobiotic granulomas of the subcutaneous tissue and dermis.…”

Section: Surgical Scar Necrobiosis Lipoidicamentioning

confidence: 93%