We report a 10-year-old boy presenting with palmoplantar pustular psoriasis, resistant to topical and systemic treatments, who was successfully treated with subcutaneous etanercept (0.4 mg/kg) twice a week for 1 month. Maintenance therapy was extended for 18 months in combination with near ultraviolet light therapy without any adverse effect. Etanercept may be a safe and effective alternative for severe palmoplantar pustular psoriasis in children.
Two layered zirconium phosphates containing Ru(bpy)(3)(2+) mono- or diphosphonates and diquat, {Ru(bpy)(3)(2+)[]/ZrP/DQ(++)} and Ru(bpy)(3)(2+)[]/ZrP/DQ(++), covalently attached to the phosphate layers exhibit notable photovoltaic response (the maximum V(OC), J(SC), and FF were 0.093 V, 16.8 microA cm(-2) and 0.33, respectively). The photocurrent spectra indicate that the photovoltaic response is due predominantly to direct photoexcitation of gamma-ZrP host, Ru(bpy)(3)(2+) and diquat acting as hole and electron traps, respectively, for the charge separated state of the semiconductor.
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