Near-infrared spectroscopy: a tool to monitor cerebral hemodynamic and metabolic changes after cardiac arrest in rats

Real-time quantitative monitoring of cerebral blood flow by laser speckle contrast imaging after cardiac arrest with targeted temperature management

“…In our study, hypothermia was induced immediately after ROSC, resulting in a prolonged hyperemia phase, and delayed but augmented hypoperfusion. This was consistent with reports from both an asphyxia CA model with hypothermia induced before CA 39 and a bilateral occlusion and release of the common carotid arteries (BCCAO) model with hypothermia induced during global ischemia. 40 Little is known about the etiology and management of hyperemia immediately after ROSC.…”

Correlations between hemodynamic, oxygenation and tissue perfusion parameters during asphyxial cardiac arrest and resuscitation in a pediatric animal model

“…22 Additionally, Lima et al, in adults, found that thenar eminence saturation had a poor correlation with lactate clearance and was not correlated with global hemodynamic parameters. 23 We are not aware of prior studies about the potential usefulness of renal NIRS in shock or cardiac arrest.…”

Hemodynamic, respiratory, and perfusion parameters during asphyxia, resuscitation, and post-resuscitation in a pediatric model of cardiac arrest

“…Prior studies have assessed the potential usefulness of brain NIRS for the control of brain perfusion-oxygenation status in children during cardiac surgery and in animal models of newborn asphyxia and CA [12,[28][29][30], but no studies have reported results of NIRS during cardiac arrest and subsequent CPR. Our results indicate that brain saturation decreases during asphyxial CA, its values remain low during CPR, and partially restore after ROSC, a profile that suggests a persistence of tissue hypoxia after resuscitation that could contribute to brain damage and poor neurological outcome.…”