Near-Infrared Responsive Doxorubicin Loaded Hollow Mesoporous Prussian Blue Nanoparticles Combined with Dissolvable Hyaluronic Acid Microneedle System for Human Oral Squamous Cell Carcinoma Therapy

Xu, Yuntao; Ying, Hao; Li, Wei; Xiao, Yao; Zhou, Tianlin; Hu, Danrong; Liu, Qingya; Zhou, Xinran; Qian, Zhiyong

doi:10.1166/jbn.2020.2917

Cited by 8 publications

(5 citation statements)

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“…It also showed significant synergistic effect of thermal ablation and chemotherapy in mouse tumor model. [125] ICG, as a small molecule photosensitizer, has excellent photothermal conversion efficiency and has been widely used in PTT of tumors. Such as HA MN mediated poly(lactic-co-glycolic acid) nanotherapeutic systems co-loaded with paclitaxel and ICG, [126] and monomethoxy poly(ethylene glycol)-polycaprolactone (MPEG-PCL) NPs co-loaded with 5-FU and ICG, [127] both exhibit excellent tumor inhibition effects in percutaneous chemotherapy and PTT synergistic therapy of tumors.…”

Section: Combination Therapymentioning

confidence: 99%

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Advances in Natural Polymer‐Based Transdermal Drug Delivery Systems for Tumor Therapy

Han

Liu

et al. 2023

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As an alternative to traditional oral and intravenous injections with limited efficacy, transdermal drug delivery (TDD) has shown great promise in tumor treatment. Over the past decade, natural polymers have been designed into various nanocarriers due to their excellent biocompatibility, biodegradability, and easy availability, providing more options for TDD. In addition, surface functionalization modification of the rich functional groups of natural polymers, which in turn are developed into targeted and stimulus‐responsive functional materials, allows precise delivery of drugs to tumor sites and release of drugs in response to specific stimuli. It not only improves the treatment efficiency of tumor but also reduces the toxic and side effects to normal tissues. Therefore, the development of natural polymer‐based TDD (NPTDD) systems has great potential in tumor therapy. In this review, the mechanism of NPTDD systems such as penetration enhancers, nanoparticles, microneedles, hydrogels and nanofibers prepared from hyaluronic acid, chitosan, sodium alginate, cellulose, heparin and protein, and their applications in tumor therapy are overviewed. This review also outlines the future prospects and current challenges of NPTDD systems for local treatment tumors.

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Section: Combination Therapymentioning

confidence: 99%

“…It also showed significant synergistic effect of thermal ablation and chemotherapy in mouse tumor model. [ 125 ]…”

Section: Application Of Nptdd Systems In Tumor Therapymentioning

confidence: 99%

Advances in Natural Polymer‐Based Transdermal Drug Delivery Systems for Tumor Therapy

Han

Liu

et al. 2023

Small

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“…Triple-negative breast cancer [ 212] Microneedle patch HA Nanoparticle loaded with 5-fluorouracil and indocyanine green DMNs, NIR controlled drug release from nanoparticles Skin cancers like human epidermoid cancer and melanoma [ 213] Microneedle patch HA DOX DMNs, NIR responsive release Oral squamous cell carcinoma [ 214] Microneedle patch HA, pH-sensitive dextran nanoparticles Zn phthalocyanine, checkpoint inhibitor anti-CTLA4 antibody Self-degradable microneedle patch PDT/photoimmunotherapy [ 215] Microneedle patch HA-polyvinyl alcohol-polyvinyl pyrrolidone…”

Section: Nir Photothermal Ablation Of Tumormentioning

confidence: 99%

Tailoring Hyaluronic Acid Hydrogels for Biomedical Applications

Luo,

Wang,

et al. 2023

Adv Funct Materials

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Hyaluronic acid (HA) is an attractive anionic polysaccharide polymer with inherent pharmacological properties and versatile chemical groups for modification. Due to their water retention ability, biocompatibility, biodegradation, cluster of differentiation‐44 targeting, and highly designable capacity, HA hydrogels have been an emerging biomaterial, showing tailoring performance in terms of chemical modifications and hydrogel forms. Various preparation technologies have been developed for the fabrication of the tailoring HA hydrogels with unique structures and functions. They have been utilized in diverse biomedical applications like drug delivery and tissue engineering scaffolds. Herein, this review comprehensively summarizes the HA derivatives with different molecule weights and functional modifications. Then the various fabrication methods to obtain tailoring hydrogels in the forms of nanogel, nanofiber, microparticle, microneedle patch, injectable hydrogel, and scaffold are reviewed as well. The emphasis is focused on the shining biomedical applications of these tailoring HA hydrogels in anti‐bacteria, anti‐inflammation, wound healing, cancer treatment, regenerative medicine, psoriasis treatment, diagnosis, etc. The potentials and prospects are subsequently given to inspire further investigation, aiming at accelerating product translation from research to clinic.

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“…HMPBs&DOX@HAMNs can heat the tumor tissue, maintain its internal temperature above 60 °C, and regulate the release behavior of DOX. HMPBs&DOX@HAMNs displayed a strong anti-tumor effect in vivo and in vitro [ 116 ].…”

Section: Organic Nanoparticlesmentioning

confidence: 99%

Progress of Nanomaterials-Based Photothermal Therapy for Oral Squamous Cell Carcinoma

Qin

Sun

Bai

et al. 2022

IJMS

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Oral squamous cell carcinoma (OSCC) is one of the top 15 most prevalent cancers worldwide. However, the current treatment models for OSCC (e.g., surgery, chemotherapy, radiotherapy, and combination therapy) present several limitations: damage to adjacent healthy tissue, possible recurrence, low efficiency, and severe side effects. In this context, nanomaterial-based photothermal therapy (PTT) has attracted extensive research attention. This paper reviews the latest progress in the application of biological nanomaterials for PTT in OSCC. We divide photothermal nanomaterials into four categories (noble metal nanomaterials, carbon-based nanomaterials, metal compounds, and organic nanomaterials) and introduce each category in detail. We also mention in detail the drug delivery systems for PTT of OSCC and briefly summarize the applications of hydrogels, liposomes, and micelles. Finally, we note the challenges faced by the clinical application of PTT nanomaterials and the possibility of further improvement, providing direction for the future research of PTT in OSCC treatment.

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Near-Infrared Responsive Doxorubicin Loaded Hollow Mesoporous Prussian Blue Nanoparticles Combined with Dissolvable Hyaluronic Acid Microneedle System for Human Oral Squamous Cell Carcinoma Therapy

Cited by 8 publications

References 0 publications

Advances in Natural Polymer‐Based Transdermal Drug Delivery Systems for Tumor Therapy

Advances in Natural Polymer‐Based Transdermal Drug Delivery Systems for Tumor Therapy

Tailoring Hyaluronic Acid Hydrogels for Biomedical Applications

Progress of Nanomaterials-Based Photothermal Therapy for Oral Squamous Cell Carcinoma

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