NCDs and the WHO Essential Medicines Lists: children need universal health coverage too

Gray, Nicola J.; Chanoine, Jean‐Pierre; Farmer, Mychelle; Jarvis, Jordan; Armstrong, Kate; Barr, Ronald D.; Faunce, Thomas; Lashley, P Michele; Ndikumwenayo, Francois; Hauerslev, Marie; Karekezi, Catherine; Klein, Jonathan D.; Ambrose, Rosalind E; Patel, Kiran A.; Raza, Syed Muhammad Muslim; Siriwardana, Vtsk; Smith, Sherri L.; Wyber, Rosemary

doi:10.1016/s2352-4642(19)30294-9

Cited by 3 publications

(5 citation statements)

References 8 publications

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“…The current study observed that the update of WHO EMLc has been has been done from time to time but the case was not identical with Indian EMLc [ 8 - 10 ]. As per WHO, essential medicines for a population, meet the primacy health care requirements and are selected on the basis of prevalence and public health significance of a disease with proven efficacy and safety [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

“…In front of each medicine, the strength and dosage form which is appropriate for children is mentioned. The list also consists of therapeutic alternative for various medicines [ 8 ].…”

Section: Methodsmentioning

confidence: 99%

“…The WHO Model Lists of Essential Medicines are updated every two years by the Expert Committee on Selection and Use of Essential Medicines. Currently, 8th EMLc is in practice which was introduced in the year 2021 [ 8 ]. Indian Academy of Paediatrics (IAP) has also introduced Indian EMLc in October 2011 in collaboration with WHO.…”

Section: Introductionmentioning

confidence: 99%

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Indian Essential Medicine List for Children: Time to Revisit

Singhal¹,

Dutta²,

Thakker³

et al. 2023

Cureus

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Background: The majority of the under five mortality rate (U5MR) in India were due to treatable causes and could have been prevented by providing quality medicines. Availability and affordability of medicine can be improved by the introduction of essential medicine concepts.Purpose: The current study was carried out to compare the latest edition of the WHO essential medicine list for children (EMLc) with that of Indian EMLc to determine the need to update the Indian EMLc.Methods: A descriptive observational study was carried out in the Department of Pharmacology of a tertiary care hospital. The latest edition of WHO EMLc (8 th ) was compared with the latest edition of Indian EMLc (1 st ) in terms of inclusion of categories or subcategories, the number of medicines in each category or subcategories, medicines which are present in WHO EMLc but missing in Indian EMLc and vice versa.Results: In total 134 medicines are present in Indian EMLc as compared to 350 medicines in WHO EMLc. The important categories which are completely missing in Indian EMLc are medicines for reproductive health and perinatal care, peritoneal dialysis solution, medicines for mental and behavioral disorders, and medicines for diseases of joints. The important medicines which are not included in Indian EMLc are bedaquilline, delaminid, cefixime, piperacillin+tazobactum, vancomycin, acyclovir, azathioprine, cisplatin, and filgrastim. Important vaccines including rotavirus, cholera, hepatitis, and typhoid vaccine are not mentioned in Indian EMLc. Conclusion:There is an urgent need to update the Indian EMLc in order to promote access to pediatric medicine and facilitate the rational use of medicines.

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Section: Discussionmentioning

confidence: 99%

“…In front of each medicine, the strength and dosage form which is appropriate for children is mentioned. The list also consists of therapeutic alternative for various medicines [ 8 ].…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Indian Essential Medicine List for Children: Time to Revisit

Singhal¹,

Dutta²,

Thakker³

et al. 2023

Cureus

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“…ese lists can be potentially powerful instruments to ensure that medicines are available, accessible, and of good quality, resulting in strengthening health equity [16]. Inclusion of more endocrine medications in WHO EMLs may promote the adoption of more medicines by individual countries within their national EML.…”

Section: Discussionmentioning

confidence: 99%

“…Creating these lists will not only reflect the relative disease burden but also highlight commonly used therapeutic interventions that need to be made affordable, accessible, and available. These lists can be potentially powerful instruments to ensure that medicines are available, accessible, and of good quality, resulting in strengthening health equity [ 16 ]. Inclusion of more endocrine medications in WHO EMLs may promote the adoption of more medicines by individual countries within their national EML.…”

Section: Discussionmentioning

confidence: 99%

Availability and Access to Medications for Puberty Induction and Maintenance in Adolescents with Hypogonadism in the Arab Region

Deeb

Alsaffar

Hamza

et al. 2022

International Journal of Clinical Practice

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Background. Inducing puberty in hypogonadal patients enables achieving normal final adult height and healthy bone mass accrual and improves fertility potential. Reliable availability and access to medicines remain a challenge around the world, particularly in low-income countries. Aim. We aimed to describe the availability/access to medications used for inducing and maintaining puberty in centers within the Arab region. Method. A cross-sectional survey was conducted using a link to an online questionnaire, which was emailed to paediatric endocrinologists in the Arab region. The questionnaire consisted of three questions related to the availability of various forms of sex hormones. Results. 99 physicians from 16 countries participated in the study. The commonest available form of estrogen was conjugated estrogen (29% of centers), followed by ethinylestradiol (26%). Depot estradiol was available in 11 centers, while topical estrogen preparations of gel and patches were available in 6 and 10 centers, respectively. Medroxy progesterone was available in 26% of the centers, followed by norethisterone (24%). The combined forms of oral and transdermal patches of estrogen/progesterone were available in 35% and 9% of centers, respectively. Intramuscular testosterone (Sustanon) was the most commonly available preparation of testosterone, followed by the depot injection (Nebido), oral testosterone, and testosterone gel and cream. Conclusions. We report the first available data on medications used for puberty induction and maintenance in paediatric hypogonadism in the Arab region. Recommended preparations for this purpose are not widely available. Creating an essential list of medications used in paediatric endocrinology disorders might improve availability, access, and consequently practice.

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Availability of Medications Used for Puberty Induction and Maintenance in Adolescents with Hypogonadism in the Arab Region

Deeb

Alsaffar

Hamza

et al. 2020

Preprint

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Purpose Inducing puberty in hypogonadal patients enables achieving normal final adult height, healthy bone mass accrual and improves fertility potential. Reliable availability and access to medicines remain a challenge around the world, particularly in low income countries. We aim to study the availability/access to medications used for inducing and maintaining puberty in centers within the Arab region. Patients and Methods A cross-sectional survey was conducted using a link to an online questionnaire which was emailed to paediatric endocrinologists in the Arab region. The questionnaire consisted of three questions related to availability of various forms of sex hormones. Results 99 physicians from 16 countries participated in the study. The commonest available form of estrogen was conjugated estrogen (29% of centers) followed by ethinylestradiol in 26%. Depot estradiol was available in 11centers while topical estrogen preparations of gel and patches were available in 6 and 10 centers respectively. Medroxy progesterone was available in 26% of the centers followed by noresthisterone (24%). The combined forms of oral and transdermal patches of estrogen/progestorne were available in 35 and 9% of centers. Intramuscular testosterone (Sustanon) was the most commonly available preparation of testosterone followed by the depot injection (Nebido), oral testosterone and testosterone gel and cream. Conclusions We report the first availability data of medications used for puberty induction and maintenance in paediatric hypogonadism in the Arab region. Recommended preparations for this purpose are not widely available. Creating essential list of medications used in paediatric endocrinology disorders might improve availability, access and consequently practice.

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NCDs and the WHO Essential Medicines Lists: children need universal health coverage too

Cited by 3 publications

References 8 publications

Indian Essential Medicine List for Children: Time to Revisit

Indian Essential Medicine List for Children: Time to Revisit

Availability and Access to Medications for Puberty Induction and Maintenance in Adolescents with Hypogonadism in the Arab Region

Availability of Medications Used for Puberty Induction and Maintenance in Adolescents with Hypogonadism in the Arab Region

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