Nature of Genital Discharge and pH of Cervical Mucus and Uterine Flushing Before and After Treatment in Endometritis Affected Cows

Palanisamy, M.; Napolean, R. Ezakial; Selvaraju, M.; Balasubramanian, GA; Manokaran, Kalaivani

doi:10.5455/ijlr.20141006071857

Cited by 5 publications

(6 citation statements)

References 3 publications

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“…The mean pH value revealed a significant decline towards normal in all the therapeutic groups from pre-treatment to post-treatment. This similar decline in the pH of cervico-vaginal mucus is seen in studies conducted by Palanisamy et al (2014) [22] and Puro et al (2018) [26] .…”

Section: Discussionsupporting

confidence: 84%

Study on efficacy of different intrauterine treatments of endometritis in buffaloes

Chandra,

Mohan,

Venkataramana

et al. 2024

Int. J. Adv. Biochem. Res.

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A study was carried out in dairy farms in and around Hyderabad. The buffaloes with the history of abnormal uterine discharge and repeat breeders that did not conceive in earlier services were selected through clinico-gynaecological examinations, estimation of pH of cervico-vaginal mucus and white side test of cervico vaginal mucus to diagnose the endometritis. A total of Thirty-two buffaloes with endometritis were selected and randomly divided into four groups of eight animals in each group. The buffaloes of group-I not given any treatment and were inseminated at observed estrus, Group II were administered intrauterine Lenovo I.U. 60ml intrauterine for 3 consecutive days from day of estrus, Group III were administered intrauterine E. coli lipopolysaccharide 100μg in 20ml of sterile phosphate buffer saline single dose on the day of estrus and Group IV were administered intrauterine Oyster glycogen 500mg in 30ml phosphate buffer saline single dose on the day of estrus and artificial insemination was done during subsequent observed estrus when white side test was found negative. According to the results it was concluded that the buffaloes with abnormal cervico-vaginal discharges and with conception failure could be effectively treated with the intrauterine infusion of E.coli LPS and Oyster glycogen to improve the fertility and conception rate. The E.coli LPS and Oyster glycogen can also be used effectively as immunomodulator with highest safety to the endometrium and without causing any systemic effects.

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Section: Discussionsupporting

confidence: 84%

Study on efficacy of different intrauterine treatments of endometritis in buffaloes

Chandra,

Mohan,

Venkataramana

et al. 2024

Int. J. Adv. Biochem. Res.

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“…The pH value of genital discharge could be used for the diagnosis of endometritis in cattle (Palanisamy et al, 2014).In the present study pH value ranged from 8.53 to 8.57 before treatment. The change in pH of uterine fluid to the alkaline side is usually due to the presence of metabolites of bacteria and inflammatory exudates associated with uterine infection.…”

Section: Discussionmentioning

confidence: 56%

“…This may be due to the decrease of high pH value after theend of treatment noticed in our study for theCefazolin group. This decrease of pH value can be critical for the survival of sperm and fetus in the uterus (Palanisamy et al, 2014;Kumar et al, 2014).…”

Section: Discussionmentioning

confidence: 99%

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Εταιρεία¹

2021

J Hellenic Vet Med Soc

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“…The change in pH of uterine fluid to the alkaline side is usually due to the presence of metabolites of bacteria and inflammatory exudates associated with uterine infection. This increase of pH is not suitable for the survival of sperm and fetus in the uterus (Palanisamy et al, 2014;Kumar et al, 2014). In this study, the pH value decreased after treatment, and this reduction was significant after the first dose of Cefazolin, while Cephalexin needed two doses to be effective.…”

Section: Discussionmentioning

confidence: 99%

Effect of Cefazolin on endometrial cytology and reagent test strips parameters in bovine endometritis

Barakat

Shawky

Absy

et al. 2021

J Hellenic Vet Med Soc

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Endometritis is one of uterine disorders in dairy cows causing low fertility. This study explored effects of intrauterine (IU) infusion of Cefazolin on endometrial cytology and reagent test strips parameters (leukocyte esterase [LE] and pH) in bovine subclinical endometritis. A total of 90 cows at 49-56 days in milk (DIM) diagnosed for subclinical endometritis were divided randomlyinto three groups, group I (n = 35), treated with IU infusion of 2 grams Cefazolin (Zinol ®, Pharco) diluted with 50 ml saline; group II (n = 28), treated with IU infusion of 2 gramsCephalexin (Ceporex®, GlaxoSmithKline) diluted with 50 ml saline; group III (n = 27), cows kept as untreated control. Cytological examination and reagent test strips were performed in uterine material derived with the cotton swab technique before treatment program and repeated two times later, in 10 days interval. The cows were artificially inseminated at first oestrous after the end of treatment program and conception rates were evaluated. After the end of treatment program, polymorphonuclear cells (PMN) decreased significantly (P <0.05) in Cefazolin and Cephalexin groups (3.23% and 4.39% respectively) compared tocontrol (24.89%) group, also means of LE in these groups became significantly (P<0.05) lower. The Ph value decreased after treatment, this reduction was significant after the first dose of Cefazolin, while in Cephalexin reduction of pH became significant after second dose. Cefazolin had conception rate (77.14%) significantly (P<0.05) higher than cephalexin and control groups (57.14% and 25.93% respectively). Cefazolin and Cephalexin decrease uterine PMN, LE concentration. The pH value after treatment by Cefazolin was lower than in Cephalexin. Moreover, treatment with Cefazolin resulted in a significantly higher conception rate. Thus, Cefazolin is recommended for the treatment of subclinical endometritis in dairy cows.

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Nature of Genital Discharge and pH of Cervical Mucus and Uterine Flushing Before and After Treatment in Endometritis Affected Cows

Cited by 5 publications

References 3 publications

Study on efficacy of different intrauterine treatments of endometritis in buffaloes

Study on efficacy of different intrauterine treatments of endometritis in buffaloes

Whole issue

Effect of Cefazolin on endometrial cytology and reagent test strips parameters in bovine endometritis

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