Nature et rôle des éléments traces dans les calculs urinaires

Hannache, B.; Boutefnouchet, A.; Bazin, Dominique; Daudon, Michel; Foy, Eddy; Rouzière, Stéphan; Dahdouh, Aïcha

doi:10.1016/j.purol.2014.09.038

Cited by 13 publications

(6 citation statements)

References 15 publications

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“…A large number of trace elements have been quantitatively detected in kidney stones [45,101,102]. The first paper on trace elements in urine was published in 1963 [103].…”

Section: Discussionmentioning

confidence: 99%

SEM-EDX micro-analysis and FTIR infrared microscopy by ATR of a bladder stone from the IIIth millennium BC from the B1S passage-grave of the necropolis in Chenon (Charente, France)

Colmont¹,

Bazin²,

Daudon³

2022

Comptes Rendus. Chimie

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Here is a case of bladder stone of average size dated to the Late Neolithic period, found in the multiple burial of the B1S passage-grave in Chenon (Charente, France). Chemical analysis showed a mixed composition. The core, intermediate and surface envelopes consist in calcium phosphate apatite associated with whitlockite and amorphous carbonated calcium phosphate, all clarified by Fourier Transform InfraRed spectroscopy. Calcium phosphatic stones are characteristic of communities, such as those of the Neolithic period, where the diet was rich in cereal carbohydrates and poor in animal proteins. The excavation of such extra-skeletal objects is an event that is particularly interesting as it provides documents on the history of diseases and diets in ancient populations. The complete set of data suggests that this bladder stone was formed during a urinary tract infection with a germ possessing a very active urease.

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“…A large number of trace elements have been quantitatively detected in kidney stones [45,101,102]. The first paper on trace elements in urine was published in 1963 [103].…”

Section: Discussionmentioning

confidence: 99%

SEM-EDX micro-analysis and FTIR infrared microscopy by ATR of a bladder stone from the IIIth millennium BC from the B1S passage-grave of the necropolis in Chenon (Charente, France)

Colmont¹,

Bazin²,

Daudon³

2022

Comptes Rendus. Chimie

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“…After application of standardization, these authors show that it is possible to obtain a quantitative microanalysis with detection limits of 400 ppm (Mg, P, S, Cl, K, Ca), 500 ppm (Na), and 1200 ppm (F). Such spectroscopy can thus bring information regarding the presence of light elements such Mg or F, which are generally not discussed in the case of X-ray fluorescence experiments induced by photons [154][155][156].…”

Section: Energy-dispersive X-ray Spectroscopymentioning

confidence: 99%

Scanning electron microscopy—a powerful imaging technique for the clinician

Bazin¹,

Bouderlique²,

Daudon³

et al. 2022

Comptes Rendus. Chimie

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Since its first use several decades ago, scanning electron microscopy has been used in numerous investigations dedicated to biological systems. This contribution focuses on observations on pathological calcifications in order to review several major applications of primary importance to the clinician. Among these, we highlight such observations as medical diagnostic tools in pathologies arising from primary hyperoxaluria and urinary infections.

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“…This technique has been used to characterise different kinds of PC. [122][123][124][125] First, note that investigation of calcification chemistry is hampered by the difficulty of quickly and systematically locating sites. A recent publication shows that XRF spectroscopy can be used to locate micro-calcifications within tissue specimens.…”

Section: X-ray Fluorescencementioning

confidence: 99%

Physicochemistry in medicine: some selected examples

Bazin

Daudon

2019

J. Spectral Imaging

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Research on pathological calcifications constitutes an exciting topic at the interface between physics, chemistry and medicine. The relationship between their physicochemical characteristics and the pathology responsible for their formation offers a unique opportunity to perform a significant medical diagnosis, to assess the interaction between drugs and these biological entities as well as to develop new drugs. Regarding synchrotron radiation, the emergence of microbeam allows the clinician to perform an early diagnosis. Indeed, we will start this review with a clinical case where Fourier transform infrared spectroscopy using synchrotron radiation as a probe allowed the clinician to save the kidney function of a patient. Following this example, we will see that investigations on pathological calcifications constitute an elegant way to gather major information on different public health problems such type 2 diabetes as well as on rare diseases. To attain this goal, this mini-review dedicated to structural and chemical investigations and based on selected and recent data collected through techniques using third generation synchrotron radiation as a probe is proposed to the reader.

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Nature et rôle des éléments traces dans les calculs urinaires

Cited by 13 publications

References 15 publications

SEM-EDX micro-analysis and FTIR infrared microscopy by ATR of a bladder stone from the IIIth millennium BC from the B1S passage-grave of the necropolis in Chenon (Charente, France)

SEM-EDX micro-analysis and FTIR infrared microscopy by ATR of a bladder stone from the IIIth millennium BC from the B1S passage-grave of the necropolis in Chenon (Charente, France)

Scanning electron microscopy—a powerful imaging technique for the clinician

Physicochemistry in medicine: some selected examples

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