Natural Substances from Higher Plants as Potential Anti-MRSA Agents

Horváth, Györgyi; Farkas, Ágnes; Papp, Nóra; Bencsik, Tímea; Ács, Kamilla; Gyergyák, Kinga; Kocsis, Béla

doi:10.1016/b978-0-444-63603-4.00003-6

Cited by 10 publications

(8 citation statements)

References 172 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…1 Saha etal (33) referred the antibacterial activity of propolis to the flavonoid content which causes structural and functional damage; interfere with cell membrane integrity, inhibit the bacterial mobility, enzyme activity, cell-division and alters cell membrane permeability. Moreover; Horvath etal (55) attributed antibacterial activity to decrease the mRNA synthesis which leads to stopping of protein production killing the microorganism from within. While Xie et al (56) explained antibacterial mechanisms of flavonoids due to inhibition of biofilm formation and break down the bacterial and biofilm attachment to dentin, energy metabolism inhibition and attenuation of the pathogenicity.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of antimicrobial activity of manually agitate (nano- chitosan and nano- propolis) against Enterococcus faecalis in comparison with sodium hypochlorite: an in-vitro study

Moukarab

2020

Egyptian Dental Journal

View full text Add to dashboard Cite

Aim:The purpose of this study was to evaluate in an in-vitro model the antibacterial efficacy of manually agitated nano-chitosan and nano-propolis as root canal irrigation protocols in comparison to manually agitated sodium hypochlorite against Enterococcus Faecalis. Material and Methods:The root canals of 50 single rooted human premolars were flattened to a standard length of 18mm cleaned and shaped to a size F5 Protaper, apices closed with composite, fixed into an Eppendorf vial with silicon impression material, autoclaved, and randomly assigned to the test groups (n=10) . Negative control was autoclaved and microbial analyzed. The other 40 specimens were contaminated with freshly prepared suspension of E. Faecalis and incubated for 4 weeks and equally divided into 4 groups positive control group (n=10) was not subjected to any further treatments, group A final irrigation with 5.25% NaOCl, group B final irrigation with nanochitosan and group C final irrigation with nano-propolis ; all irrigation protocols were combined with manual agitation with well fitted gutta perch cone for 2 minutes under a laminar flow hood. Microbial samples were collected from all the root specimens and colony forming units were counted and transformed into log CFU. The collected data were statistically analyzed.Results: There was no statistical significant difference in log CFU count between group A (treated with NaOCl) and group B, C (treated with CNP and PNP) while groups A, B, C showed statistically significant difference from positive control group with (p > 0.05). Conclusion:With in the limitations of the present study it can be concluded that all irrigation protocols had efficient antibacterial effect against E. faecalis.Manually agitated (CNP or PNP) can be considered as a more safe, efficient, and simple alternative instead of sodium hypochlorite against E. faecalis.

show abstract

Section: Discussionmentioning

confidence: 99%

Evaluation of antimicrobial activity of manually agitate (nano- chitosan and nano- propolis) against Enterococcus faecalis in comparison with sodium hypochlorite: an in-vitro study

Moukarab

2020

Egyptian Dental Journal

View full text Add to dashboard Cite

show abstract

“…Propolis is a natural hive defensive resinous substance produced by honeybees from plant exudates, beeswax, and bee secretions. Propolis which is also called "bee-glue" is collected by honeybees from a variety of plant resinous secretions, i.e., gums, resins, leaf buds, and mucilage [31,32], from numerous plant species, such as conifers, pine, palm, poplar, and birch [33], and is used to build structures in their hives and to fill the holes in to protect their hives from microbes and other external threats [34]. It has a long history in medicine as a wound healing agent and having antibacterial, anticancer, anti-inflammatory, and anti-infective effects since 300 BC [35][36][37][38][39].…”

Section: Biochemical Composition (Phenolic Acids Flavonoids Vitaminmentioning

confidence: 99%

“…It has a long history in medicine as a wound healing agent and having antibacterial, anticancer, anti-inflammatory, and anti-infective effects since 300 BC [35][36][37][38][39]. It is reported that its composition significantly varies according to the plant sources and season and it is composed of about 50% resin, 30% wax, 10% essential oils, 5% pollen, and 5% other substances [34].…”

Section: Biochemical Composition (Phenolic Acids Flavonoids Vitaminmentioning

confidence: 99%

Biochemical Composition of Propolis and Its Efficacy in Maintaining Postharvest Storability of Fresh Fruits and Vegetables

Kahramanoğlu

Okatan

Wan

2020

Journal of Food Quality

View full text Add to dashboard Cite

Propolis, also called “bee-glue,” is a natural resinous substance produced by honeybees from plant exudates, beeswax, and bee secretions in order to defend the hives. It has numerous phenolic compounds with more than 250 identified chemical compounds in its composition, which are also known to significantly vary according to the plant sources and season. Moreover, it has a long history in the traditional and scientific medicine as having antibacterial, anticancer, anti-inflammatory, anti-infective, and wound healing effects since 300 BC. In addition to its nutritional and health-promoting effects, it has been reported to improve the postharvest storability of fresh fruits, vegetables, and processed food products. Herein, the biochemical composition and the efficacy of propolis in maintaining the postharvest storability of fresh food products were discussed to provide comprehensive guide to farmers and food processing and storage sectors and to scientists. This review paper also highlights the important points to which special attention should be given in further studies in order to be able to use propolis to develop biopreservatives industrially and for quality preservation during storage.

show abstract

“…Em destaque, a bactéria Staphylococcus aureus é classificada como Gram-positivo e adquiriu resistência à meticilina, dando origem a S. aureus resistente à meticilina MRSA, sendo a segunda causa mais comum de Infecções Relacionadas à Assistência à Saúde (IRAS) nos EUA, de acordo com um relatório do Centers for Disease Control and Prevention (CDC) (Miller, Munita & Arias, 2014;Malani, 2014;Horváth et al, 2016;Gomes et al, 2018;Pugazhendhi et al, 2020). No entanto, as estratégias para lidar com essa problemática vão desde a necessidade uma maior compreensão desses patógenos a buscas de novas formas de controle e eliminação dessa infecção no hospedeiro.…”

Section: Introductionunclassified

Prospecção científica e tecnológica da Tabebuia reseoalba (Ipê-branco)

Pereyra

Santos

Rocha

et al. 2021

RSD

View full text Add to dashboard Cite

A Tabebuia roseoalba, conhecida popularmente como Ipê-branco, uma planta nativa do cerrado e pantanal brasileiro. Por possuir inúmeras substâncias de interesse terapêutico, há perspectivas de servirem como alternativa no controle de infecções. Com o intuito de verificar a importância dos extratos de Tabebuia roseoalba no cunho científico, foram feitas pesquisas a fim de se confirmar a relevância que o presente trabalho apresenta como inovação tecnológica. Os resultados encontrados nas bases de dados Science Direct e Pubmed, assim como patentes encontradas nos bancos de patentes World Intelectual Property Organization (WIPO) e Instituto Nacional da Propriedade Industrial (INPI), foram métodos eficazes para a construção dessa Prospecção. A partir das palavras-chaves antimicrobianos, resistência bacteriana, Bignoniaceae, Tabebuia e Tabebuia roseoalba, na língua inglesa e portuguesa, quando necessário, na base de patentes WIPO revelou 135.638 patentes para antimicrobial, 78.108 para bacterial resistence, 69 para Bignoniaceae, 167 para Tabebuia e 0 para Tabebuia roseoalba. No INPI foram obtidas 1.377 para antimicrobiano, 2.510 para resistência bacteriana, 38 para Bignoniaceae, 31 para Tabebuia e 3 para Tabebuia roseoalba. A partir dos resultados obtidos mediante as buscas de patentes acerca da utilização de potenciais antimicrobiano de Tabebuia roseoalba para o combate de agentes patogênicos, pode-se concluir que o estudo forneceu dados de prospecção científico-tecnológico, visto que auxiliou como uma boa ferramenta para a realização da presente pesquisa pode-se ressaltar a importância da análise prospecção tecnológica, como um meio benéfico no qual pode promover a capacidade de organizar a pesquisa inovadora com base nos interesses e necessidades da sociedade.

show abstract

Natural Substances from Higher Plants as Potential Anti-MRSA Agents

Cited by 10 publications

References 172 publications

Evaluation of antimicrobial activity of manually agitate (nano- chitosan and nano- propolis) against Enterococcus faecalis in comparison with sodium hypochlorite: an in-vitro study

Evaluation of antimicrobial activity of manually agitate (nano- chitosan and nano- propolis) against Enterococcus faecalis in comparison with sodium hypochlorite: an in-vitro study

Biochemical Composition of Propolis and Its Efficacy in Maintaining Postharvest Storability of Fresh Fruits and Vegetables

Prospecção científica e tecnológica da Tabebuia reseoalba (Ipê-branco)

Contact Info

Product

Resources

About